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Zinc in PDB 4k0s: Structure of Hcaix Mimic (Hcaii with 5 Mutations in Active Site) in Complex with Acetazolamide
Enzymatic activity of Structure of Hcaix Mimic (Hcaii with 5 Mutations in Active Site) in Complex with Acetazolamide
All present enzymatic activity of Structure of Hcaix Mimic (Hcaii with 5 Mutations in Active Site) in Complex with Acetazolamide:
4.2.1.1;
4.2.1.1;
Protein crystallography data
The structure of Structure of Hcaix Mimic (Hcaii with 5 Mutations in Active Site) in Complex with Acetazolamide, PDB code: 4k0s
was solved by
S.Biswas,
R.Mckenna,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 29.11 / 1.80 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 42.124, 41.463, 72.669, 90.00, 103.89, 90.00 |
| R / Rfree (%) | 16.7 / 21.3 |
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure of Hcaix Mimic (Hcaii with 5 Mutations in Active Site) in Complex with Acetazolamide
(pdb code 4k0s). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of Hcaix Mimic (Hcaii with 5 Mutations in Active Site) in Complex with Acetazolamide, PDB code: 4k0s:
In total only one binding site of Zinc was determined in the Structure of Hcaix Mimic (Hcaii with 5 Mutations in Active Site) in Complex with Acetazolamide, PDB code: 4k0s:
Zinc binding site 1 out of 1 in 4k0s
Go back to
Zinc Binding Sites List in 4k0s
Zinc binding site 1 out
of 1 in the Structure of Hcaix Mimic (Hcaii with 5 Mutations in Active Site) in Complex with Acetazolamide
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Structure of Hcaix Mimic (Hcaii with 5 Mutations in Active Site) in Complex with Acetazolamide within 5.0Å range:
|
Reference:
S.Biswas,
D.West,
M.Pinard,
R.Mckenna.
Developing Isoform Specific Inhibitors Against Hcaix Using Caix Mimic To Be Published.
Page generated: Sun Oct 27 01:34:11 2024
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