Zinc in PDB 2xzq: Crystal Structure Analysis of the Anti-(4-Hydroxy-3- Nitrophenyl)-Acetyl Murine Germline Monoclonal Antibody BBE6.12H3 Fab Fragment in Complex with A Phage Display Derived Dodecapeptide Yqlrpnaetlrf

The structure of Crystal Structure Analysis of the Anti-(4-Hydroxy-3- Nitrophenyl)-Acetyl Murine Germline Monoclonal Antibody BBE6.12H3 Fab Fragment in Complex with A Phage Display Derived Dodecapeptide Yqlrpnaetlrf, PDB code: 2xzq was solved by T.Khan, D.M.Salunke, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50 / 2.40
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	55.920, 65.280, 113.560, 90.00, 90.19, 90.00
R / Rfree (%)	24.07 / 25.06

The binding sites of Zinc atom in the Crystal Structure Analysis of the Anti-(4-Hydroxy-3- Nitrophenyl)-Acetyl Murine Germline Monoclonal Antibody BBE6.12H3 Fab Fragment in Complex with A Phage Display Derived Dodecapeptide Yqlrpnaetlrf (pdb code 2xzq). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure Analysis of the Anti-(4-Hydroxy-3- Nitrophenyl)-Acetyl Murine Germline Monoclonal Antibody BBE6.12H3 Fab Fragment in Complex with A Phage Display Derived Dodecapeptide Yqlrpnaetlrf, PDB code: 2xzq:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure Analysis of the Anti-(4-Hydroxy-3- Nitrophenyl)-Acetyl Murine Germline Monoclonal Antibody BBE6.12H3 Fab Fragment in Complex with A Phage Display Derived Dodecapeptide Yqlrpnaetlrf


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure Analysis of the Anti-(4-Hydroxy-3- Nitrophenyl)-Acetyl Murine Germline Monoclonal Antibody BBE6.12H3 Fab Fragment in Complex with A Phage Display Derived Dodecapeptide Yqlrpnaetlrf within 5.0Å range: probe atom residue distance (Å) B Occ H:Zn1221 b:32.0 occ:1.00 NE2 H:GLN39 3.1 30.7 1.0 CA H:GLY44 3.5 33.3 1.0 N H:GLY44 3.8 36.3 1.0 CG H:GLN39 3.9 28.6 1.0 CD H:GLN39 3.9 31.1 1.0 CZ L:PHE89 4.0 15.3 1.0 O L:HOH2010 4.0 33.6 1.0 C H:GLY44 4.1 31.5 1.0 CA H:PRO41 4.3 39.5 1.0 O H:GLY44 4.5 30.8 1.0 CD2 H:LEU45 4.5 28.9 1.0 CE1 L:PHE89 4.6 14.0 1.0 N H:LEU45 4.7 29.1 1.0 N H:GLY42 4.8 40.9 1.0 N H:PRO41 4.8 39.0 1.0 O H:ARG40 4.8 38.3 1.0 CG H:LEU45 4.9 26.9 1.0 OE1 H:GLN39 5.0 29.2 1.0

Zinc binding site 2 out of 2 in the Crystal Structure Analysis of the Anti-(4-Hydroxy-3- Nitrophenyl)-Acetyl Murine Germline Monoclonal Antibody BBE6.12H3 Fab Fragment in Complex with A Phage Display Derived Dodecapeptide Yqlrpnaetlrf


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure Analysis of the Anti-(4-Hydroxy-3- Nitrophenyl)-Acetyl Murine Germline Monoclonal Antibody BBE6.12H3 Fab Fragment in Complex with A Phage Display Derived Dodecapeptide Yqlrpnaetlrf within 5.0Å range: probe atom residue distance (Å) B Occ P:Zn1221 b:17.4 occ:1.00 C P:THR9 3.2 74.2 1.0 O P:GLU8 3.3 73.6 1.0 CD H:ARG50 3.5 26.3 1.0 O P:THR9 3.7 28.2 1.0 CE1 H:HIS35 3.7 24.4 1.0 CH2 L:TRP93 4.0 19.8 1.0 NE2 H:HIS35 4.1 24.3 1.0 NH1 H:ARG50 4.1 21.2 1.0 CB H:ARG50 4.1 20.2 1.0 CZ3 L:TRP93 4.1 19.9 1.0 CZ3 H:TRP33 4.1 27.6 1.0 C P:GLU8 4.2 73.6 1.0 CG H:ARG50 4.3 22.1 1.0 CZ2 H:TRP47 4.3 16.6 1.0 CE3 H:TRP33 4.4 28.9 1.0 CA P:THR9 4.4 73.8 1.0 NE1 L:TRP98 4.5 15.1 1.0 CB H:ALA59 4.6 20.0 1.0 NE H:ARG50 4.6 26.0 1.0 N P:THR9 4.6 73.7 1.0 OE1 P:GLU8 4.7 72.8 1.0 CD P:GLU8 4.8 70.9 1.0 ND1 H:HIS35 4.8 24.1 1.0 CZ2 L:TRP93 4.8 21.2 1.0 CZ H:ARG50 4.8 26.4 1.0 CD1 L:TRP98 4.9 14.3 1.0 CH2 H:TRP47 5.0 14.9 1.0

T.Khan, D.M.Salunke. Structural Elucidation of the Mechanistic Basis of Degeneracy in the Primary Humoral Response. J.Immunol. V. 188 1819 2012.
ISSN: ISSN 0022-1767
PubMed: 22266283
DOI: 10.4049/JIMMUNOL.1102701