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Zinc in PDB 2mwx: The Ring Domain of Human Promyelocytic Leukemia Protein (Pml)

Zinc Binding Sites:

The binding sites of Zinc atom in the The Ring Domain of Human Promyelocytic Leukemia Protein (Pml) (pdb code 2mwx). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the The Ring Domain of Human Promyelocytic Leukemia Protein (Pml), PDB code: 2mwx:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 2mwx

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Zinc binding site 1 out of 2 in the The Ring Domain of Human Promyelocytic Leukemia Protein (Pml)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of The Ring Domain of Human Promyelocytic Leukemia Protein (Pml) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn201

b:73.4
occ:1.00
SG A:CYS80 2.2 1.3 1.0
SG A:CYS77 2.2 71.5 1.0
SG A:CYS57 2.3 15.6 1.0
SG A:CYS60 2.6 52.1 1.0
H A:CYS77 2.7 51.4 1.0
HB2 A:CYS60 2.8 33.4 1.0
HB2 A:CYS80 2.8 33.2 1.0
HG3 A:GLN59 2.9 42.1 1.0
CB A:CYS80 3.1 40.4 1.0
CB A:CYS60 3.3 0.5 1.0
HG2 A:GLN59 3.3 2.1 1.0
HB3 A:CYS77 3.4 34.4 1.0
CB A:CYS77 3.4 61.4 1.0
CB A:CYS57 3.5 41.3 1.0
HB2 A:CYS57 3.5 61.0 1.0
CG A:GLN59 3.6 15.3 1.0
N A:CYS77 3.6 43.1 1.0
HB3 A:CYS57 3.7 34.1 1.0
HG A:LEU76 3.7 52.3 1.0
HB3 A:CYS80 3.8 70.1 1.0
H A:CYS60 3.9 23.4 1.0
HB3 A:CYS60 4.0 1.3 1.0
H A:CYS80 4.0 20.4 1.0
HE21 A:GLN59 4.1 4.4 1.0
CA A:CYS77 4.1 32.2 1.0
N A:CYS60 4.1 15.4 1.0
CA A:CYS80 4.2 55.4 1.0
CD A:GLN59 4.2 43.0 1.0
HB2 A:CYS77 4.3 45.5 1.0
HA A:LEU76 4.3 61.4 1.0
CA A:CYS60 4.3 70.4 1.0
HA A:CYS80 4.3 55.1 1.0
N A:CYS80 4.4 74.1 1.0
NE2 A:GLN59 4.4 4.5 1.0
HB3 A:LEU76 4.6 33.4 1.0
O A:CYS77 4.6 5.3 1.0
C A:LEU76 4.7 5.3 1.0
H A:GLN59 4.7 51.4 1.0
CG A:LEU76 4.7 11.3 1.0
C A:CYS77 4.7 12.0 1.0
HA A:CYS60 4.7 14.1 1.0
CA A:LEU76 4.8 40.2 1.0
HD23 A:LEU76 4.8 72.4 1.0
CB A:GLN59 4.8 64.4 1.0
C A:GLN59 4.8 44.0 1.0
CA A:CYS57 4.9 34.3 1.0
CB A:LEU76 4.9 12.2 1.0
HA A:CYS77 5.0 44.3 1.0

Zinc binding site 2 out of 2 in 2mwx

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Zinc binding site 2 out of 2 in the The Ring Domain of Human Promyelocytic Leukemia Protein (Pml)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of The Ring Domain of Human Promyelocytic Leukemia Protein (Pml) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn202

b:64.3
occ:1.00
SG A:CYS91 1.7 42.4 1.0
NE2 A:HIS74 2.5 21.4 1.0
SG A:CYS88 2.5 5.4 1.0
SG A:CYS72 2.6 21.2 1.0
HB3 A:CYS72 2.8 44.2 1.0
HB2 A:CYS91 2.8 74.4 1.0
CB A:CYS91 2.8 11.2 1.0
HD2 A:HIS74 3.0 2.1 1.0
CD2 A:HIS74 3.1 64.5 1.0
CB A:CYS72 3.1 4.5 1.0
HB3 A:CYS88 3.2 21.0 1.0
HB2 A:CYS72 3.3 15.2 1.0
CB A:CYS88 3.5 52.1 1.0
CE1 A:HIS74 3.6 34.2 1.0
HA A:CYS91 3.6 44.0 1.0
HB3 A:CYS91 3.6 73.4 1.0
CA A:CYS91 3.7 71.1 1.0
HE1 A:HIS74 4.0 12.2 1.0
H A:CYS91 4.1 75.1 1.0
N A:CYS91 4.2 70.2 1.0
HB2 A:CYS88 4.2 35.3 1.0
CG A:HIS74 4.3 44.2 1.0
ND1 A:HIS74 4.5 75.2 1.0
CA A:CYS72 4.6 70.5 1.0
HA A:CYS88 4.6 2.4 1.0
CA A:CYS88 4.6 24.2 1.0
O A:CYS72 4.7 41.5 1.0
O A:CYS88 4.7 45.3 1.0
C A:CYS88 5.0 10.2 1.0
HA A:CYS72 5.0 2.0 1.0

Reference:

S.Y.Huang, C.F.Chang, P.J.Fang, M.T.Naik, P.Guntert, H.M.Shih, T.H.Huang. The Ring Domain of Human Promyelocytic Leukemia Protein (Pml) J.Biomol.uc(Nmr) 2015.
ISSN: ISSN 0925-2738
PubMed: 25627356
DOI: 10.1007/S10858-015-9901-3
Page generated: Wed Aug 20 04:28:16 2025

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