Zinc in PDB 9uie: Electronic Microscopy Structure of Human SCHLAFEN14-E211A Dimer in Complex with Dsrna

The binding sites of Zinc atom in the Electronic Microscopy Structure of Human SCHLAFEN14-E211A Dimer in Complex with Dsrna (pdb code 9uie). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Electronic Microscopy Structure of Human SCHLAFEN14-E211A Dimer in Complex with Dsrna, PDB code: 9uie:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Electronic Microscopy Structure of Human SCHLAFEN14-E211A Dimer in Complex with Dsrna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Electronic Microscopy Structure of Human SCHLAFEN14-E211A Dimer in Complex with Dsrna within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1001 b:68.1 occ:1.00 ND1 B:HIS282 2.1 23.9 1.0 SG B:CYS318 2.3 43.8 1.0 SG B:CYS284 2.3 51.3 1.0 SG B:CYS319 2.3 34.1 1.0 CE1 B:HIS282 2.8 23.4 1.0 CG B:HIS282 3.3 24.4 1.0 CB B:CYS319 3.3 31.2 1.0 CB B:CYS318 3.5 37.3 1.0 CB B:HIS282 3.8 25.2 1.0 CB B:CYS284 3.9 41.9 1.0 N B:CYS319 3.9 31.9 1.0 NE2 B:HIS282 4.0 22.1 1.0 CD B:PRO288 4.1 32.1 1.0 C B:CYS318 4.1 38.3 1.0 CA B:HIS282 4.1 22.3 1.0 CA B:CYS319 4.2 26.7 1.0 CD2 B:HIS282 4.3 25.3 1.0 N B:CYS284 4.3 38.2 1.0 CA B:CYS318 4.4 30.6 1.0 N B:PHE283 4.4 26.8 1.0 O B:CYS318 4.6 40.7 1.0 CA B:CYS284 4.7 41.6 1.0 C B:HIS282 4.8 24.4 1.0 CE2 B:PHE317 4.9 27.1 1.0 CG B:PRO288 4.9 32.1 1.0 N B:CYS318 5.0 27.9 1.0

Zinc binding site 2 out of 2 in the Electronic Microscopy Structure of Human SCHLAFEN14-E211A Dimer in Complex with Dsrna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Electronic Microscopy Structure of Human SCHLAFEN14-E211A Dimer in Complex with Dsrna within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn1001 b:62.2 occ:1.00 ND1 C:HIS282 2.0 24.2 1.0 SG C:CYS319 2.3 34.5 1.0 SG C:CYS318 2.3 32.0 1.0 SG C:CYS284 2.3 39.5 1.0 CE1 C:HIS282 2.8 22.3 1.0 CG C:HIS282 3.2 23.1 1.0 CB C:CYS318 3.3 21.8 1.0 CB C:CYS319 3.4 31.2 1.0 CB C:CYS284 3.6 37.2 1.0 N C:CYS319 3.8 29.4 1.0 CB C:HIS282 3.8 23.8 1.0 N C:CYS284 4.0 37.8 1.0 NE2 C:HIS282 4.0 19.9 1.0 CA C:HIS282 4.0 22.8 1.0 CD C:PRO288 4.1 27.2 1.0 N C:PHE283 4.2 22.8 1.0 C C:CYS318 4.2 30.4 1.0 CD2 C:HIS282 4.2 22.8 1.0 CA C:CYS319 4.2 28.5 1.0 CA C:CYS318 4.3 21.8 1.0 CA C:CYS284 4.4 37.7 1.0 C C:HIS282 4.6 26.4 1.0 CE2 C:PHE317 4.9 22.5 1.0 CA C:LYS287 5.0 32.0 1.0

M.Li, D.Sun, W.Hao, H.Fu, Y.Zhang, Z.Li, B.Qin, Y.Wang, S.Cui. Human Schlafen 14 Cleavage of Short Double-Stranded Rnas Underpins Its Antiviral Activity. Adv Sci 01727 2025.
ISSN: ESSN 2198-3844
PubMed: 40642785
DOI: 10.1002/ADVS.202501727