Zinc in PDB 9ofb: Cryoem Structure of CAD1 Bound with CA4 and Atp, Symmetry Expanded Dimer Refined Against A Composite Map

All present enzymatic activity of Cryoem Structure of CAD1 Bound with CA4 and Atp, Symmetry Expanded Dimer Refined Against A Composite Map:
3.5.4.4;

The structure of Cryoem Structure of CAD1 Bound with CA4 and Atp, Symmetry Expanded Dimer Refined Against A Composite Map also contains other interesting chemical elements:

Magnesium

(Mg)

4 atoms

The binding sites of Zinc atom in the Cryoem Structure of CAD1 Bound with CA4 and Atp, Symmetry Expanded Dimer Refined Against A Composite Map (pdb code 9ofb). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Cryoem Structure of CAD1 Bound with CA4 and Atp, Symmetry Expanded Dimer Refined Against A Composite Map, PDB code: 9ofb:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Cryoem Structure of CAD1 Bound with CA4 and Atp, Symmetry Expanded Dimer Refined Against A Composite Map


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryoem Structure of CAD1 Bound with CA4 and Atp, Symmetry Expanded Dimer Refined Against A Composite Map within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn702 b:105.8 occ:1.00 CE1 A:HIS461 1.6 101.9 1.0 NE2 A:HIS262 2.3 60.2 1.0 NE2 A:HIS260 2.3 65.1 1.0 NE2 A:HIS461 2.3 105.9 1.0 ND1 A:HIS461 2.4 100.3 1.0 OD1 A:ASP548 2.7 77.7 1.0 CE1 A:HIS260 3.0 64.0 1.0 CE1 A:HIS262 3.0 64.3 1.0 CD2 A:HIS461 3.3 103.1 1.0 CG A:HIS461 3.3 103.5 1.0 CD2 A:HIS262 3.5 55.8 1.0 CD2 A:HIS260 3.5 57.6 1.0 C5 A:ATP701 3.6 108.6 1.0 C6 A:ATP701 3.7 107.2 1.0 CE1 A:HIS485 3.8 88.2 1.0 CG A:ASP548 3.8 78.5 1.0 N6 A:ATP701 3.9 104.0 1.0 N7 A:ATP701 3.9 108.3 1.0 C4 A:ATP701 4.1 109.8 1.0 N1 A:ATP701 4.1 110.9 1.0 OD2 A:ASP548 4.2 87.7 1.0 ND1 A:HIS260 4.2 62.4 1.0 ND1 A:HIS262 4.2 57.2 1.0 C8 A:ATP701 4.5 106.5 1.0 CG A:HIS262 4.5 56.7 1.0 CG A:HIS260 4.5 56.4 1.0 C2 A:ATP701 4.5 111.5 1.0 ND1 A:HIS485 4.5 92.6 1.0 N3 A:ATP701 4.6 108.9 1.0 NE2 A:HIS485 4.6 93.4 1.0 N9 A:ATP701 4.6 109.7 1.0 CB A:HIS461 4.7 99.6 1.0 NE A:ARG350 5.0 56.0 1.0

Zinc binding site 2 out of 2 in the Cryoem Structure of CAD1 Bound with CA4 and Atp, Symmetry Expanded Dimer Refined Against A Composite Map


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryoem Structure of CAD1 Bound with CA4 and Atp, Symmetry Expanded Dimer Refined Against A Composite Map within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn702 b:126.2 occ:1.00 OD2 B:ASP548 2.1 79.5 1.0 NE2 B:HIS260 2.3 59.7 1.0 NE2 B:HIS262 2.3 72.6 1.0 CE1 B:HIS461 2.5 86.7 1.0 CG B:ASP548 3.0 79.1 1.0 CE1 B:HIS260 3.1 61.8 1.0 CD2 B:HIS262 3.1 67.7 1.0 N6 B:ATP701 3.2 104.4 1.0 NE2 B:HIS461 3.3 91.6 1.0 OD1 B:ASP548 3.3 84.8 1.0 C6 B:ATP701 3.4 106.4 1.0 CE1 B:HIS262 3.4 66.5 1.0 CD2 B:HIS260 3.4 60.0 1.0 ND1 B:HIS461 3.6 85.0 1.0 C5 B:ATP701 3.7 103.8 1.0 CE1 B:HIS485 3.9 79.7 1.0 N1 B:ATP701 4.0 107.6 1.0 N7 B:ATP701 4.0 100.5 1.0 ND1 B:HIS260 4.3 65.6 1.0 CG B:HIS262 4.3 65.8 1.0 CB B:ASP548 4.4 73.1 1.0 ND1 B:HIS262 4.4 63.2 1.0 CG B:HIS260 4.5 61.3 1.0 CD2 B:HIS461 4.5 87.7 1.0 C4 B:ATP701 4.5 104.5 1.0 CA B:ASP548 4.6 67.7 1.0 NE2 B:HIS485 4.6 79.5 1.0 CG B:HIS461 4.7 86.9 1.0 C2 B:ATP701 4.7 105.8 1.0 ND2 B:ASN549 4.8 72.5 1.0 ND1 B:HIS485 4.8 84.7 1.0 C8 B:ATP701 4.9 104.6 1.0

Y.Zhao, H.Li. Sequential Conformational Activation of A Carf-Fused Adenosine Deaminase By Cyclic Oligoadenylates To Be Published.