Zinc in PDB 9ivy: Pseudomonas Aeruginosa Histidinol Dehydrogenase with Nadh and Zn

All present enzymatic activity of Pseudomonas Aeruginosa Histidinol Dehydrogenase with Nadh and Zn:
1.1.1.23;

The structure of Pseudomonas Aeruginosa Histidinol Dehydrogenase with Nadh and Zn, PDB code: 9ivy was solved by G.B.Choudhury, S.Datta, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	27.56 / 2.33
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	67.299, 89.527, 139.871, 90, 90, 90
R / Rfree (%)	20 / 24.3

The binding sites of Zinc atom in the Pseudomonas Aeruginosa Histidinol Dehydrogenase with Nadh and Zn (pdb code 9ivy). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Pseudomonas Aeruginosa Histidinol Dehydrogenase with Nadh and Zn, PDB code: 9ivy:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Pseudomonas Aeruginosa Histidinol Dehydrogenase with Nadh and Zn


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Pseudomonas Aeruginosa Histidinol Dehydrogenase with Nadh and Zn within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn504 b:73.8 occ:1.00 OD2 A:ASP367 1.6 41.3 1.0 OH A:TYR144 2.0 54.1 1.0 CE1 A:HIS268 2.2 40.4 0.3 NE2 A:HIS268 2.3 38.6 0.3 NE2 B:HIS426 2.3 26.9 1.0 OE2 A:GLU363 2.7 62.5 1.0 CG A:ASP367 2.8 48.9 1.0 CE1 B:HIS426 2.9 25.6 1.0 CZ A:TYR144 3.1 60.6 1.0 ND1 A:HIS268 3.4 40.6 0.3 CD2 A:HIS268 3.5 41.3 0.3 CD2 B:HIS426 3.5 27.4 1.0 OD1 A:ASP367 3.6 55.4 1.0 CD A:GLU363 3.7 57.4 1.0 CE1 A:TYR144 3.8 48.8 1.0 CB A:ASP367 3.9 36.6 1.0 OE1 A:GLN265 3.9 45.6 1.0 CE2 A:TYR144 4.0 49.2 1.0 CG A:HIS268 4.1 38.8 0.3 O A:SER264 4.1 28.2 1.0 OE1 A:GLU363 4.1 54.1 1.0 ND1 B:HIS426 4.1 29.4 1.0 CG B:HIS426 4.5 31.1 1.0 CD A:GLN265 4.7 45.9 1.0 CA A:GLN265 4.7 32.8 1.0 C A:SER264 4.7 30.4 1.0 CG A:GLU363 4.9 39.6 1.0 OG A:SER264 5.0 37.1 1.0

Zinc binding site 2 out of 4 in the Pseudomonas Aeruginosa Histidinol Dehydrogenase with Nadh and Zn


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Pseudomonas Aeruginosa Histidinol Dehydrogenase with Nadh and Zn within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn505 b:96.8 occ:1.00 CE1 A:HIS334 2.0 56.0 1.0 NE2 A:HIS334 2.3 55.9 1.0 ND1 A:HIS334 3.2 45.0 1.0 CD2 A:HIS334 3.7 36.8 1.0 CG A:HIS334 4.1 36.7 1.0 CG A:GLU333 4.7 47.1 1.0 OE2 A:GLU333 4.8 58.8 1.0 CD A:GLU333 4.9 63.8 1.0

Zinc binding site 3 out of 4 in the Pseudomonas Aeruginosa Histidinol Dehydrogenase with Nadh and Zn


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Pseudomonas Aeruginosa Histidinol Dehydrogenase with Nadh and Zn within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn502 b:44.7 occ:1.00 OE2 B:GLU363 1.9 44.4 1.0 OD2 B:ASP367 1.9 53.3 1.0 NE2 A:HIS426 2.3 37.0 1.0 NE2 B:HIS268 2.3 56.4 1.0 CD B:GLU363 2.9 40.8 1.0 CG B:ASP367 2.9 47.2 1.0 CD2 B:HIS268 3.1 46.6 1.0 CE1 A:HIS426 3.2 36.8 1.0 CG B:GLU363 3.2 44.3 1.0 CD2 A:HIS426 3.2 35.6 1.0 CE1 B:HIS268 3.3 44.5 1.0 OD1 B:ASP367 3.4 51.8 1.0 OE1 B:GLU363 4.0 44.0 1.0 CB B:ASP367 4.1 43.5 1.0 CG B:HIS268 4.3 49.2 1.0 ND1 B:HIS268 4.3 50.4 1.0 ND1 A:HIS426 4.3 35.5 1.0 CG A:HIS426 4.4 32.2 1.0 O B:SER264 4.4 34.9 1.0 CB B:GLU363 4.8 38.0 1.0 C B:SER264 5.0 31.3 1.0 NE2 B:GLN265 5.0 40.6 1.0 O B:GLU363 5.0 35.3 1.0

Zinc binding site 4 out of 4 in the Pseudomonas Aeruginosa Histidinol Dehydrogenase with Nadh and Zn


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Pseudomonas Aeruginosa Histidinol Dehydrogenase with Nadh and Zn within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn503 b:96.5 occ:1.00 CE1 B:HIS374 2.1 74.4 1.0 NE2 B:HIS334 2.3 50.5 1.0 NE2 B:HIS374 2.3 74.8 1.0 CE1 B:HIS334 2.8 51.3 1.0 ND1 B:HIS374 3.4 64.0 1.0 CD2 B:HIS334 3.6 37.6 1.0 CD2 B:HIS374 3.6 68.8 1.0 O7N B:NAI501 3.7 55.3 1.0 ND1 B:HIS334 4.0 42.8 1.0 CG B:HIS374 4.2 65.9 1.0 N7N B:NAI501 4.3 57.5 1.0 C7N B:NAI501 4.4 58.4 1.0 CG B:HIS334 4.5 35.7 1.0

G.B.Choudhury, A.Saha, S.Datta. Hisd in P Aeruginosa To Be Published.