Zinc in PDB 9eil: SIRT6 Bound to An H3K27AC Nucleosome

All present enzymatic activity of SIRT6 Bound to An H3K27AC Nucleosome:
2.3.1.286;

The binding sites of Zinc atom in the SIRT6 Bound to An H3K27AC Nucleosome (pdb code 9eil). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the SIRT6 Bound to An H3K27AC Nucleosome, PDB code: 9eil:

Zinc binding site 1 out of 1 in the SIRT6 Bound to An H3K27AC Nucleosome


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of SIRT6 Bound to An H3K27AC Nucleosome within 5.0Å range: probe atom residue distance (Å) B Occ K:Zn401 b:142.0 occ:1.00 SG K:CYS177 2.3 101.7 1.0 SG K:CYS141 2.3 114.4 1.0 SG K:CYS144 2.3 89.7 1.0 SG K:CYS166 2.3 115.2 1.0 CB K:CYS166 2.9 112.4 1.0 CB K:CYS177 3.1 92.2 1.0 CB K:CYS141 3.2 109.2 1.0 CB K:CYS144 3.8 87.3 1.0 N K:GLY179 4.1 113.3 1.0 N K:CYS144 4.1 88.9 1.0 CA K:GLY179 4.3 115.0 1.0 CA K:CYS166 4.4 111.0 1.0 CA K:CYS177 4.5 90.0 1.0 CG1 K:VAL168 4.5 98.4 1.0 CA K:CYS144 4.5 87.7 1.0 OG1 K:THR146 4.6 109.9 1.0 CB K:LYS143 4.6 83.6 1.0 C K:CYS177 4.6 90.5 1.0 CB K:THR146 4.6 108.3 1.0 CA K:CYS141 4.7 109.4 1.0 N K:ARG178 4.7 97.7 1.0

Z.A.Wang, J.Markert, S.D.Whedon, M.Y.Abeywardana, X.Sheng, E.Nam, K.Lee, M.Chen, A.Waterbury, Y.Zhao, L.Farnung, P.A.Cole. Structural and Enzymatic Plasticity of SIRT6 Deacylase Activity. J.Biol.Chem. V. 301 08446 2025.
ISSN: ESSN 1083-351X
PubMed: 40147774
DOI: 10.1016/J.JBC.2025.108446