Zinc in PDB 9ebz: Escherichia Coli Carbonic Anhydrase 2 in Space Group C222(1)

All present enzymatic activity of Escherichia Coli Carbonic Anhydrase 2 in Space Group C222(1):
4.2.1.1;

The structure of Escherichia Coli Carbonic Anhydrase 2 in Space Group C222(1), PDB code: 9ebz was solved by M.R.Rankin, J.L.Smith, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.89 / 2.66
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	113.227, 119.145, 161.01, 90, 90, 90
R / Rfree (%)	26.1 / 28.7

The binding sites of Zinc atom in the Escherichia Coli Carbonic Anhydrase 2 in Space Group C222(1) (pdb code 9ebz). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Escherichia Coli Carbonic Anhydrase 2 in Space Group C222(1), PDB code: 9ebz:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Escherichia Coli Carbonic Anhydrase 2 in Space Group C222(1)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Escherichia Coli Carbonic Anhydrase 2 in Space Group C222(1) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn301 b:79.1 occ:1.00 OD2 A:ASP44 2.0 72.9 1.0 NE2 A:HIS98 2.0 68.7 1.0 SG A:CYS101 2.2 76.4 1.0 SG A:CYS42 2.3 51.3 1.0 CE1 A:HIS98 2.7 67.6 1.0 CG A:ASP44 3.0 74.8 1.0 CB A:CYS101 3.1 58.8 1.0 CD2 A:HIS98 3.2 62.9 1.0 CB A:ASP44 3.4 68.9 1.0 CA A:CYS101 3.4 61.7 1.0 CB A:CYS42 3.6 59.8 1.0 N A:GLY102 3.8 66.0 1.0 ND1 A:HIS98 3.9 60.7 1.0 C A:CYS101 4.0 63.1 1.0 OD1 A:ASP44 4.1 73.8 1.0 CG A:HIS98 4.2 59.5 1.0 N A:ASP44 4.5 66.0 1.0 CA A:ASP44 4.6 70.1 1.0 N A:GLY103 4.6 58.0 1.0 N A:CYS101 4.7 67.3 1.0 N A:ALA67 4.9 64.1 1.0 CA A:ALA67 4.9 56.6 1.0 CA A:CYS42 5.0 60.1 1.0 CA A:GLY102 5.0 69.1 1.0

Zinc binding site 2 out of 4 in the Escherichia Coli Carbonic Anhydrase 2 in Space Group C222(1)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Escherichia Coli Carbonic Anhydrase 2 in Space Group C222(1) within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn301 b:79.1 occ:1.00 OD2 B:ASP44 2.0 77.7 1.0 NE2 B:HIS98 2.0 70.8 1.0 SG B:CYS42 2.2 64.2 1.0 SG B:CYS101 2.2 79.4 1.0 CE1 B:HIS98 2.6 68.5 1.0 CG B:ASP44 3.0 75.3 1.0 CB B:CYS101 3.1 65.2 1.0 CD2 B:HIS98 3.2 65.6 1.0 CB B:CYS42 3.4 56.1 1.0 CB B:ASP44 3.4 72.6 1.0 CA B:CYS101 3.5 67.4 1.0 ND1 B:HIS98 3.8 63.7 1.0 N B:GLY102 3.9 67.3 1.0 CG B:HIS98 4.1 61.9 1.0 OD1 B:ASP44 4.1 72.5 1.0 C B:CYS101 4.1 64.3 1.0 N B:ASP44 4.5 66.5 1.0 CA B:ASP44 4.6 72.6 1.0 N B:GLY103 4.7 63.3 1.0 N B:CYS101 4.7 73.2 1.0 N B:ALA67 4.7 57.2 1.0 CA B:CYS42 4.8 60.1 1.0 CA B:ALA67 4.8 54.6 1.0

Zinc binding site 3 out of 4 in the Escherichia Coli Carbonic Anhydrase 2 in Space Group C222(1)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Escherichia Coli Carbonic Anhydrase 2 in Space Group C222(1) within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn301 b:83.6 occ:1.00 OD2 C:ASP44 2.0 72.9 1.0 NE2 C:HIS98 2.0 80.6 1.0 SG C:CYS42 2.3 73.9 1.0 SG C:CYS101 2.3 65.3 1.0 CE1 C:HIS98 2.5 79.5 1.0 CG C:ASP44 3.0 69.5 1.0 CB C:CYS101 3.2 76.4 1.0 CD2 C:HIS98 3.3 81.5 1.0 CB C:CYS42 3.4 66.2 1.0 CB C:ASP44 3.4 71.0 1.0 CA C:CYS101 3.6 80.0 1.0 ND1 C:HIS98 3.8 78.6 1.0 N C:GLY102 4.1 77.1 1.0 OD1 C:ASP44 4.1 60.8 1.0 CG C:HIS98 4.1 80.7 1.0 C C:CYS101 4.3 77.7 1.0 N C:ASP44 4.4 70.2 1.0 CA C:ASP44 4.6 73.1 1.0 N C:ALA67 4.6 65.4 1.0 N C:GLY103 4.7 75.7 1.0 CA C:ALA67 4.7 64.2 1.0 CA C:CYS42 4.8 65.8 1.0 N C:CYS101 4.9 78.2 1.0

Zinc binding site 4 out of 4 in the Escherichia Coli Carbonic Anhydrase 2 in Space Group C222(1)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Escherichia Coli Carbonic Anhydrase 2 in Space Group C222(1) within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn301 b:81.2 occ:1.00 OD2 D:ASP44 2.0 82.4 1.0 NE2 D:HIS98 2.0 91.0 1.0 SG D:CYS42 2.3 70.7 1.0 SG D:CYS101 2.3 84.9 1.0 CE1 D:HIS98 2.7 86.6 1.0 CG D:ASP44 3.1 76.2 1.0 CB D:CYS101 3.1 84.3 1.0 CD2 D:HIS98 3.2 87.2 1.0 CB D:CYS42 3.4 67.0 1.0 CA D:CYS101 3.5 85.5 1.0 CB D:ASP44 3.6 75.5 1.0 ND1 D:HIS98 3.9 86.0 1.0 N D:GLY102 4.0 76.1 1.0 OD1 D:ASP44 4.1 69.9 1.0 CG D:HIS98 4.1 85.7 1.0 C D:CYS101 4.1 81.4 1.0 N D:ALA67 4.6 58.5 1.0 N D:ASP44 4.6 70.1 1.0 N D:GLY103 4.6 82.3 1.0 CA D:ALA67 4.7 59.6 1.0 CA D:ASP44 4.7 71.7 1.0 N D:CYS101 4.8 88.7 1.0 CA D:CYS42 4.8 64.2 1.0

M.R.Rankin, J.L.Smith. Serendipitous High-Resolution Structure of Escherichia Coli Carbonic Anhydrase 2 To Be Published.