Zinc in PDB 9e8z: 4-Component Structure of Retron EC83

All present enzymatic activity of 4-Component Structure of Retron EC83:
2.7.7.49;

The binding sites of Zinc atom in the 4-Component Structure of Retron EC83 (pdb code 9e8z). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the 4-Component Structure of Retron EC83, PDB code: 9e8z:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the 4-Component Structure of Retron EC83


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of 4-Component Structure of Retron EC83 within 5.0Å range: probe atom residue distance (Å) B Occ E:Zn501 b:165.4 occ:1.00 SG E:CYS57 2.3 147.2 1.0 SG E:CYS98 2.3 153.6 1.0 SG E:CYS54 2.3 151.0 1.0 SG E:CYS116 2.3 154.2 1.0 CB E:CYS54 2.9 151.0 1.0 CB E:CYS98 3.2 153.6 1.0 CB E:CYS57 3.4 147.2 1.0 CB E:CYS116 3.7 154.2 1.0 N E:CYS57 3.7 147.2 1.0 N E:CYS98 4.0 153.6 1.0 CA E:CYS57 4.1 147.2 1.0 CA E:CYS98 4.2 153.6 1.0 CA E:CYS54 4.4 151.0 1.0 N E:GLU58 4.5 147.4 1.0 CG1 E:ILE59 4.5 146.6 1.0 C E:CYS57 4.6 147.2 1.0 C E:TYR56 4.6 152.1 1.0 CD1 E:ILE59 4.8 146.6 1.0 CA E:CYS116 4.8 154.2 1.0 N E:TYR56 4.9 152.1 1.0 C E:VAL97 4.9 156.2 1.0

Zinc binding site 2 out of 2 in the 4-Component Structure of Retron EC83


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of 4-Component Structure of Retron EC83 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn501 b:86.9 occ:1.00 CB B:CYS57 1.6 81.5 1.0 SG B:CYS98 2.3 83.8 1.0 SG B:CYS54 2.3 86.1 1.0 SG B:CYS57 2.3 81.5 1.0 CB B:CYS98 2.9 83.8 1.0 CA B:CYS57 3.0 81.5 1.0 CB B:CYS54 3.3 86.1 1.0 C B:CYS57 3.5 81.5 1.0 N B:CYS57 3.6 81.5 1.0 SG B:CYS116 3.6 84.5 1.0 CB B:CYS116 3.8 84.5 1.0 N B:GLU58 3.9 74.4 1.0 N B:CYS98 4.0 83.8 1.0 CG1 B:ILE59 4.0 73.6 1.0 CA B:CYS98 4.0 83.8 1.0 O B:CYS57 4.1 81.5 1.0 CB B:ILE59 4.5 73.6 1.0 N B:ILE59 4.5 73.6 1.0 CA B:CYS54 4.7 86.1 1.0 OG B:SER115 4.8 80.6 1.0 C B:TYR56 4.8 88.4 1.0 CA B:CYS116 4.9 84.5 1.0

C.Wang, A.D.Rish, E.G.Armbruster, J.Xie, A.B.Loveland, Z.Shen, B.Gu, A.A.Korostelev, J.Pogliano, T.M.Fu. Disassembly Activates Retron-Septu For Antiphage Defense. Science V3344 2025.
ISSN: ESSN 1095-9203
PubMed: 40504952
DOI: 10.1126/SCIENCE.ADV3344