Zinc in PDB 8wot: Cryo-Em Structure of Human SIDT1 Protein with C2 Symmetry at Low pH

The binding sites of Zinc atom in the Cryo-Em Structure of Human SIDT1 Protein with C2 Symmetry at Low pH (pdb code 8wot). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Cryo-Em Structure of Human SIDT1 Protein with C2 Symmetry at Low pH, PDB code: 8wot:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Cryo-Em Structure of Human SIDT1 Protein with C2 Symmetry at Low pH


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of Human SIDT1 Protein with C2 Symmetry at Low pH within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn907 b:118.3 occ:1.00 CE1 A:HIS800 1.9 76.3 1.0 NE2 A:HIS563 2.3 64.4 1.0 NE2 A:HIS796 2.3 73.5 1.0 NE2 A:HIS800 2.3 73.2 1.0 CD2 A:HIS796 2.3 72.0 1.0 ND1 A:HIS800 3.1 72.2 1.0 CD2 A:HIS563 3.1 64.1 1.0 CE1 A:HIS563 3.4 67.1 1.0 OD1 A:ASP574 3.5 103.8 1.0 CD2 A:HIS800 3.6 68.0 1.0 CE1 A:HIS796 3.6 69.1 1.0 CG A:HIS796 3.7 63.8 1.0 CG A:HIS800 4.0 71.0 1.0 CD1 A:TRP799 4.1 63.0 1.0 OD2 A:ASP574 4.1 103.1 1.0 NE1 A:TRP799 4.2 68.6 1.0 CG A:ASP574 4.2 105.1 1.0 ND1 A:HIS796 4.2 60.3 1.0 CG A:HIS563 4.3 59.4 1.0 ND1 A:HIS563 4.4 57.8 1.0 CB A:HIS796 4.8 66.0 1.0 O A:HIS796 4.8 76.0 1.0

Zinc binding site 2 out of 2 in the Cryo-Em Structure of Human SIDT1 Protein with C2 Symmetry at Low pH


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryo-Em Structure of Human SIDT1 Protein with C2 Symmetry at Low pH within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn907 b:112.5 occ:1.00 NE2 B:HIS563 2.3 65.0 1.0 NE2 B:HIS800 2.3 75.8 1.0 NE2 B:HIS796 2.3 70.6 1.0 CD2 B:HIS796 2.6 69.7 1.0 OD1 B:ASP574 2.8 102.2 1.0 CE1 B:HIS800 3.0 70.2 1.0 CD2 B:HIS563 3.2 64.8 1.0 OD2 B:ASP574 3.3 103.4 1.0 CE1 B:HIS563 3.3 66.7 1.0 CD2 B:HIS800 3.4 70.0 1.0 CG B:ASP574 3.5 104.0 1.0 CE1 B:HIS796 3.6 68.2 1.0 CG B:HIS796 3.9 63.6 1.0 ND1 B:HIS800 4.2 69.3 1.0 NE1 B:TRP799 4.2 67.5 1.0 CD1 B:TRP799 4.3 61.9 1.0 CG B:HIS563 4.3 60.9 1.0 ND1 B:HIS796 4.4 60.8 1.0 ND1 B:HIS563 4.4 57.4 1.0 CG B:HIS800 4.4 70.2 1.0 CE2 B:TYR562 4.9 70.0 1.0 CB B:ASP574 5.0 102.4 1.0

W.Liu, M.Tang, J.Wang, F.Wang, G.Song, X.Zhang, S.Wu, H.Ru. Structural Insights Into Cholesterol Transport and Hydrolase Activity of A Putative Human Rna Transport Protein SIDT1. Cell Discov V. 10 21 2024.
ISSN: ESSN 2056-5968
PubMed: 38378654
DOI: 10.1038/S41421-024-00647-2