Zinc in PDB 8sw0: Puromycin Sensitive Aminopeptidase

All present enzymatic activity of Puromycin Sensitive Aminopeptidase:
3.4.11.14;

The structure of Puromycin Sensitive Aminopeptidase, PDB code: 8sw0 was solved by D.W.Rodgers, S.Sampath, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.20 / 2.30
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	70.684, 257.715, 60.387, 90, 90, 90
R / Rfree (%)	22.3 / 24.1

The binding sites of Zinc atom in the Puromycin Sensitive Aminopeptidase (pdb code 8sw0). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Puromycin Sensitive Aminopeptidase, PDB code: 8sw0:

Zinc binding site 1 out of 1 in the Puromycin Sensitive Aminopeptidase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Puromycin Sensitive Aminopeptidase within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1001 b:37.4 occ:0.83 OE1 A:GLU375 2.0 71.0 1.0 O A:HOH1139 2.1 31.4 1.0 NE2 A:HIS352 2.1 45.5 1.0 NE2 A:HIS356 2.1 44.0 1.0 CD A:GLU375 2.8 67.7 1.0 CD2 A:HIS356 2.9 41.9 1.0 CE1 A:HIS352 3.0 44.4 1.0 OE2 A:GLU375 3.0 70.4 1.0 CD2 A:HIS352 3.1 45.6 1.0 CE1 A:HIS356 3.2 42.5 1.0 OE1 A:GLU319 4.1 56.2 1.0 ND1 A:HIS352 4.1 45.0 1.0 CG A:HIS356 4.1 43.1 1.0 CG A:HIS352 4.2 46.1 1.0 OE1 A:GLU353 4.2 58.9 1.0 CG A:GLU375 4.2 63.0 1.0 ND1 A:HIS356 4.2 43.1 1.0 CB A:ALA378 4.3 43.1 1.0 CD A:GLU319 4.5 53.8 1.0 OE2 A:GLU353 4.5 59.3 1.0 CA A:GLU375 4.5 51.4 1.0 CB A:GLU375 4.6 56.7 1.0 OE2 A:GLU319 4.6 54.4 1.0 CD A:GLU353 4.7 57.6 1.0

S.Madabushi, K.M.Chow, E.S.Song, A.Goswami, L.B.Hersh, D.W.Rodgers. Structure of Puromycin-Sensitive Aminopeptidase and Polyglutamine Binding. Plos One V. 18 87086 2023.
ISSN: ESSN 1932-6203
PubMed: 37440518
DOI: 10.1371/JOURNAL.PONE.0287086