Zinc in PDB 8sok: Cryo-Em Structure of Human Cst Bound to POT1(Esdl)/TPP1 in the Presence of Telomeric Ssdna

Enzymatic activity of Cryo-Em Structure of Human Cst Bound to POT1(Esdl)/TPP1 in the Presence of Telomeric Ssdna

All present enzymatic activity of Cryo-Em Structure of Human Cst Bound to POT1(Esdl)/TPP1 in the Presence of Telomeric Ssdna:
2.7.7.48; 3.4.22.28; 3.4.22.29; 3.6.1.15;

Zinc Binding Sites:

The binding sites of Zinc atom in the Cryo-Em Structure of Human Cst Bound to POT1(Esdl)/TPP1 in the Presence of Telomeric Ssdna (pdb code 8sok). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Cryo-Em Structure of Human Cst Bound to POT1(Esdl)/TPP1 in the Presence of Telomeric Ssdna, PDB code: 8sok:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 8sok

Go back to Zinc Binding Sites List in 8sok
Zinc binding site 1 out of 2 in the Cryo-Em Structure of Human Cst Bound to POT1(Esdl)/TPP1 in the Presence of Telomeric Ssdna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of Human Cst Bound to POT1(Esdl)/TPP1 in the Presence of Telomeric Ssdna within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1301

b:130.7
occ:1.00
SG A:CYS1055 2.3 101.8 1.0
SG A:CYS1062 2.3 99.7 1.0
SG A:CYS1043 2.3 100.3 1.0
SG A:CYS1046 2.3 99.1 1.0
HB2 A:CYS1062 2.3 99.7 1.0
HB3 A:CYS1043 2.6 100.3 1.0
CB A:CYS1062 2.7 99.7 1.0
CB A:CYS1043 2.8 100.3 1.0
HG A:CYS1046 2.8 99.1 1.0
HB2 A:CYS1043 2.9 100.3 1.0
HB2 A:CYS1055 2.9 101.8 1.0
HG A:CYS1055 2.9 101.8 1.0
HB3 A:CYS1062 3.0 99.7 1.0
CB A:CYS1055 3.0 101.8 1.0
HB3 A:CYS1055 3.1 101.8 1.0
HG A:CYS1043 3.2 100.3 1.0
HB2 A:ARG1057 3.4 100.4 1.0
HG A:CYS1062 3.4 99.7 1.0
HB2 A:TYR1045 3.6 92.6 1.0
H A:CYS1046 3.7 99.1 1.0
CB A:CYS1046 3.9 99.1 1.0
HB3 A:CYS1046 4.1 99.1 1.0
CA A:CYS1062 4.1 99.7 1.0
N A:CYS1046 4.2 99.1 1.0
H A:TYR1045 4.2 92.6 1.0
HA A:CYS1062 4.2 99.7 1.0
H A:ARG1057 4.3 100.4 1.0
CA A:CYS1043 4.3 100.3 1.0
HG A:CYS1050 4.3 104.5 1.0
CB A:ARG1057 4.3 100.4 1.0
O A:THR1064 4.5 103.5 1.0
CA A:CYS1055 4.5 101.8 1.0
CB A:TYR1045 4.5 92.6 1.0
HB2 A:CYS1050 4.6 104.5 1.0
HB2 A:CYS1046 4.6 99.1 1.0
HG A:SER1048 4.6 102.1 1.0
CA A:CYS1046 4.6 99.1 1.0
OG A:SER1048 4.6 102.1 1.0
HG2 A:ARG1057 4.6 100.4 1.0
HB3 A:TYR1045 4.7 92.6 1.0
HA A:CYS1043 4.7 100.3 1.0
HA A:CYS1055 4.7 101.8 1.0
HA A:LEU1058 4.8 100.8 1.0
HG3 A:ARG1057 4.8 100.4 1.0
C A:CYS1043 4.8 100.3 1.0
H A:CYS1043 4.8 100.3 1.0
C A:ARG1057 4.8 100.4 1.0
O A:CYS1046 4.9 99.1 1.0
CG A:ARG1057 4.9 100.4 1.0
HB3 A:ARG1057 4.9 100.4 1.0
N A:ARG1057 4.9 100.4 1.0
N A:TYR1045 4.9 92.6 1.0
N A:LEU1058 4.9 100.8 1.0
CA A:ARG1057 4.9 100.4 1.0
C A:CYS1062 4.9 99.7 1.0
C A:TYR1045 5.0 92.6 1.0
SG A:CYS1050 5.0 104.5 1.0

Zinc binding site 2 out of 2 in 8sok

Go back to Zinc Binding Sites List in 8sok
Zinc binding site 2 out of 2 in the Cryo-Em Structure of Human Cst Bound to POT1(Esdl)/TPP1 in the Presence of Telomeric Ssdna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryo-Em Structure of Human Cst Bound to POT1(Esdl)/TPP1 in the Presence of Telomeric Ssdna within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn701

b:156.3
occ:1.00
SG D:CYS382 2.3 111.1 1.0
SG D:CYS506 2.3 116.2 1.0
SG D:CYS385 2.3 111.9 1.0
SG D:CYS503 2.3 110.9 1.0
HG D:CYS382 2.7 111.1 1.0
HB3 D:CYS382 3.0 111.1 1.0
HG D:CYS503 3.1 110.9 1.0
CB D:CYS382 3.2 111.1 1.0
HG D:CYS385 3.2 111.9 1.0
HB3 D:CYS503 3.2 110.9 1.0
HB2 D:CYS506 3.2 116.2 1.0
CB D:CYS503 3.3 110.9 1.0
HG D:CYS506 3.3 116.2 1.0
H D:CYS385 3.4 111.9 1.0
HB2 D:CYS503 3.4 110.9 1.0
HB2 D:CYS382 3.4 111.1 1.0
CB D:CYS506 3.4 116.2 1.0
HB3 D:CYS385 3.5 111.9 1.0
CB D:CYS385 3.6 111.9 1.0
HB3 D:GLN505 3.7 107.9 1.0
H D:CYS506 3.9 116.2 1.0
HB3 D:LYS384 4.0 112.4 1.0
HB3 D:CYS506 4.1 116.2 1.0
N D:CYS385 4.1 111.9 1.0
N D:CYS506 4.2 116.2 1.0
HB2 D:CYS385 4.3 111.9 1.0
CA D:CYS385 4.4 111.9 1.0
CA D:CYS506 4.4 116.2 1.0
CA D:CYS382 4.6 111.1 1.0
CB D:GLN505 4.6 107.9 1.0
CA D:CYS503 4.7 110.9 1.0
HG12 D:VAL536 4.8 112.9 1.0
HG2 D:GLN505 4.8 107.9 1.0
HA D:CYS506 4.8 116.2 1.0
H D:GLN505 4.8 107.9 1.0
C D:GLN505 4.9 107.9 1.0
O D:CYS382 4.9 111.1 1.0
C D:CYS382 4.9 111.1 1.0
HA D:CYS382 4.9 111.1 1.0
CB D:LYS384 5.0 112.4 1.0
H D:LYS384 5.0 112.4 1.0
HB3 D:LEU387 5.0 101.1 1.0
HA D:CYS503 5.0 110.9 1.0

Reference:

S.W.Cai, H.Takai, T.Walz, T.De Lange. Structural Basis of Cst-Pol Alpha /Primase Recruitment and Regulation By POT1 at Telomeres. Biorxiv 2023.
ISSN: ISSN 2692-8205
PubMed: 37215005
DOI: 10.1101/2023.05.08.539880
Page generated: Fri Jul 28 07:32:34 2023

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy