Zinc in PDB 8s93: Crystal Structure of the pH-Th/Kinase Complex of Bruton'S Tyrosine Kinase

All present enzymatic activity of Crystal Structure of the pH-Th/Kinase Complex of Bruton'S Tyrosine Kinase:
2.7.10.2;

The structure of Crystal Structure of the pH-Th/Kinase Complex of Bruton'S Tyrosine Kinase, PDB code: 8s93 was solved by D.Y.Lin, A.H.Andreotti, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.71 / 2.10
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	38.376, 77.383, 82.323, 90, 97.98, 90
R / Rfree (%)	19.8 / 24.7

The binding sites of Zinc atom in the Crystal Structure of the pH-Th/Kinase Complex of Bruton'S Tyrosine Kinase (pdb code 8s93). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of the pH-Th/Kinase Complex of Bruton'S Tyrosine Kinase, PDB code: 8s93:

Zinc binding site 1 out of 1 in the Crystal Structure of the pH-Th/Kinase Complex of Bruton'S Tyrosine Kinase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the pH-Th/Kinase Complex of Bruton'S Tyrosine Kinase within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn702 b:153.7 occ:1.00 ND1 A:HIS143 2.1 65.2 1.0 HB3 A:CYS165 2.2 80.1 1.0 SG A:CYS165 2.3 61.0 1.0 SG A:CYS154 2.3 61.7 1.0 SG A:CYS155 2.3 74.4 1.0 CB A:CYS165 2.7 66.7 1.0 HB3 A:CYS155 2.7 69.1 1.0 CE1 A:HIS143 3.0 61.3 1.0 HA A:HIS143 3.0 59.7 1.0 H A:CYS165 3.1 73.2 1.0 CB A:CYS155 3.1 57.5 1.0 CG A:HIS143 3.1 65.5 1.0 HE1 A:HIS143 3.1 73.7 1.0 HB3 A:HIS143 3.2 66.2 1.0 HB2 A:CYS165 3.4 80.1 1.0 H A:CYS155 3.5 94.7 1.0 CB A:HIS143 3.5 55.1 1.0 N A:CYS165 3.6 61.0 1.0 CA A:HIS143 3.7 49.6 1.0 HD2 A:PRO144 3.7 66.5 1.0 N A:CYS155 3.7 78.8 1.0 HB2 A:CYS154 3.7 78.5 1.0 CA A:CYS165 3.7 56.8 1.0 CB A:CYS154 3.8 65.4 1.0 HB2 A:CYS155 3.8 69.1 1.0 HB3 A:TYR152 3.9 79.8 1.0 CA A:CYS155 4.0 79.9 1.0 NE2 A:HIS143 4.1 66.3 1.0 CD2 A:HIS143 4.2 68.8 1.0 HA A:CYS165 4.3 68.2 1.0 C A:CYS154 4.3 64.8 1.0 HA2 A:GLY164 4.3 72.7 1.0 HB3 A:CYS154 4.4 78.5 1.0 HB2 A:HIS143 4.4 66.2 1.0 H A:CYS154 4.5 75.8 1.0 HB2 A:TYR152 4.5 79.8 1.0 CD A:PRO144 4.6 55.4 1.0 CB A:TYR152 4.6 66.4 1.0 C A:GLY164 4.6 56.0 1.0 HA A:CYS155 4.6 96.0 1.0 N A:HIS143 4.6 56.4 1.0 CA A:CYS154 4.6 69.7 1.0 O A:TYR142 4.7 50.5 1.0 HD3 A:PRO144 4.7 66.5 1.0 CG A:TYR152 4.7 64.6 1.0 O A:MET163 4.8 56.4 1.0 C A:CYS165 4.8 56.9 1.0 C A:HIS143 4.8 45.1 1.0 HE2 A:HIS143 4.9 79.7 1.0 H A:GLN166 4.9 71.5 1.0 C A:TYR142 5.0 52.7 1.0 CA A:GLY164 5.0 60.5 1.0

D.Y.Lin, A.H.Andreotti. Crystal Structure of the pH-Th/Kinase Complex of Bruton'S Tyrosine Kinase To Be Published.