Zinc in PDB 8qe8: Structure of the Non-Canonical Ctlh E3 Substrate Receptor WDR26 Bound to NMNAT1 Substrate

The binding sites of Zinc atom in the Structure of the Non-Canonical Ctlh E3 Substrate Receptor WDR26 Bound to NMNAT1 Substrate (pdb code 8qe8). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of the Non-Canonical Ctlh E3 Substrate Receptor WDR26 Bound to NMNAT1 Substrate, PDB code: 8qe8:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of the Non-Canonical Ctlh E3 Substrate Receptor WDR26 Bound to NMNAT1 Substrate


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of the Non-Canonical Ctlh E3 Substrate Receptor WDR26 Bound to NMNAT1 Substrate within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn701 b:62.8 occ:1.00 ND1 A:HIS303 2.0 44.0 1.0 NE2 A:HIS320 2.0 57.7 1.0 SG A:CYS322 2.3 49.5 1.0 SG A:CYS300 2.3 48.1 1.0 CE1 A:HIS303 2.6 44.0 1.0 CE1 A:HIS320 2.8 57.7 1.0 CD2 A:HIS320 3.2 57.7 1.0 CB A:CYS300 3.3 48.1 1.0 CG A:HIS303 3.3 44.0 1.0 CB A:CYS322 3.6 49.5 1.0 CA A:HIS303 3.8 44.0 1.0 NE2 A:HIS303 3.8 44.0 1.0 CB A:HIS303 3.9 44.0 1.0 OD2 A:ASP308 4.0 58.8 1.0 ND1 A:HIS320 4.0 57.7 1.0 N A:CYS322 4.0 49.5 1.0 CD2 A:HIS303 4.2 44.0 1.0 CG A:HIS320 4.2 57.7 1.0 CA A:CYS322 4.3 49.5 1.0 C A:VAL321 4.4 54.9 1.0 N A:ASN304 4.5 44.3 1.0 N A:HIS303 4.7 44.0 1.0 CA A:CYS300 4.7 48.1 1.0 C A:HIS303 4.7 44.0 1.0 O A:VAL321 4.9 54.9 1.0 CA A:VAL321 4.9 54.9 1.0 O A:TYR302 5.0 39.9 1.0

Zinc binding site 2 out of 2 in the Structure of the Non-Canonical Ctlh E3 Substrate Receptor WDR26 Bound to NMNAT1 Substrate


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of the Non-Canonical Ctlh E3 Substrate Receptor WDR26 Bound to NMNAT1 Substrate within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn701 b:63.8 occ:1.00 ND1 B:HIS303 2.0 44.0 1.0 NE2 B:HIS320 2.0 57.4 1.0 SG B:CYS322 2.3 49.5 1.0 SG B:CYS300 2.3 48.1 1.0 CE1 B:HIS303 2.6 44.0 1.0 CE1 B:HIS320 2.8 57.4 1.0 CD2 B:HIS320 3.2 57.4 1.0 CB B:CYS300 3.3 48.1 1.0 CG B:HIS303 3.3 44.0 1.0 CB B:CYS322 3.6 49.5 1.0 NE2 B:HIS303 3.8 44.0 1.0 CA B:HIS303 3.8 44.0 1.0 CB B:HIS303 4.0 44.0 1.0 OD2 B:ASP308 4.0 57.8 1.0 N B:CYS322 4.0 49.5 1.0 ND1 B:HIS320 4.0 57.4 1.0 CD2 B:HIS303 4.2 44.0 1.0 CG B:HIS320 4.2 57.4 1.0 CA B:CYS322 4.3 49.5 1.0 C B:VAL321 4.4 54.5 1.0 N B:ASN304 4.5 43.9 1.0 CA B:CYS300 4.7 48.1 1.0 N B:HIS303 4.7 44.0 1.0 C B:HIS303 4.7 44.0 1.0 O B:VAL321 4.9 54.5 1.0 CA B:VAL321 4.9 54.5 1.0 O B:TYR302 5.0 40.2 1.0

K.V.Gottemukkala, J.Chrustowicz, D.Sherpa, S.Sepic, T.Vu, O.Karayel, A.Gross, K.Schorpp, S.Von Gronau, K.Hadian, P.J.Murray, M.Mann, B.A.Schulman, A.Alpi. Non-Canonical Substrate Targeting By the Supramolecular Ctlh E3 Ligase Reveals An WDR26-YPEL5 Regulatory Module To Be Published.