Zinc in PDB 8poa: Structure of Enterovirus A71 2A Protease

The structure of Structure of Enterovirus A71 2A Protease, PDB code: 8poa was solved by R.M.Lithgo, M.Fairhead, L.Koekemoer, J.C.Aschenbrenner, B.H.Balcomb, A.S.Godoy, P.G.Marples, X.Ni, C.W.E.Tomlinson, W.Thompson, C.Wild, D.Fearon, M.A.Walsh, F.Von Delft, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	16.09 / 1.60
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	86.128, 57.199, 64.631, 90, 95.23, 90
R / Rfree (%)	18.6 / 21

The binding sites of Zinc atom in the Structure of Enterovirus A71 2A Protease (pdb code 8poa). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of Enterovirus A71 2A Protease, PDB code: 8poa:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of Enterovirus A71 2A Protease


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Enterovirus A71 2A Protease within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn202 b:15.0 occ:1.00 ND1 A:HIS118 2.1 17.4 1.0 SG A:CYS116 2.3 12.8 1.0 SG A:CYS56 2.3 14.0 1.0 SG A:CYS58 2.3 16.4 1.0 CE1 A:HIS118 3.1 18.5 1.0 CB A:CYS58 3.1 15.3 1.0 CG A:HIS118 3.2 16.2 1.0 CB A:CYS56 3.2 13.8 1.0 CB A:CYS116 3.4 13.1 1.0 CB A:HIS118 3.5 16.5 1.0 N A:HIS118 4.0 16.0 1.0 O A:HOH440 4.1 31.9 1.0 N A:CYS58 4.2 15.9 1.0 CA A:CYS58 4.2 15.2 1.0 NE2 A:HIS118 4.3 17.9 1.0 CD2 A:HIS118 4.3 17.4 1.0 CA A:HIS118 4.4 16.0 1.0 CB A:ALA54 4.5 13.4 1.0 N A:GLN117 4.5 15.2 1.0 CA A:CYS56 4.7 13.9 1.0 CA A:CYS116 4.7 12.8 1.0 O A:HOH447 4.7 33.4 1.0 CG A:GLN117 4.7 24.2 1.0 C A:CYS116 4.8 14.6 1.0

Zinc binding site 2 out of 2 in the Structure of Enterovirus A71 2A Protease


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of Enterovirus A71 2A Protease within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn202 b:11.2 occ:0.70 ND1 B:HIS118 2.0 19.0 1.0 SG B:CYS116 2.3 15.1 1.0 SG B:CYS58 2.4 17.9 1.0 SG B:CYS56 2.4 18.1 1.0 CE1 B:HIS118 3.0 19.2 1.0 CG B:HIS118 3.1 16.5 1.0 CB B:CYS58 3.1 16.6 1.0 CB B:CYS56 3.3 17.3 1.0 CB B:CYS116 3.3 15.6 1.0 CB B:HIS118 3.5 14.7 1.0 N B:HIS118 4.1 14.7 1.0 NE2 B:HIS118 4.1 19.6 1.0 N B:CYS58 4.2 18.1 1.0 CD2 B:HIS118 4.2 18.6 1.0 CA B:CYS58 4.3 17.2 1.0 CA B:HIS118 4.4 14.7 1.0 CB B:ALA54 4.6 13.9 1.0 CD B:GLN117 4.7 20.5 1.0 CA B:CYS116 4.7 14.4 1.0 CA B:CYS56 4.7 16.9 1.0 OE1 B:GLN117 4.7 18.5 1.0 N B:GLN117 4.7 14.3 1.0 CG B:GLN117 4.8 18.0 1.0 C B:CYS116 4.9 14.8 1.0 NE2 B:GLN117 5.0 22.0 1.0

R.M.Lithgo, F.Von Delft. Structure of Ev A71 2A Protease - to Be Published To Be Published.