Zinc in PDB 8jq0: Crystal Structure of ZBTB48 ZF10-11-C in Complex with Ciita Promoter

The structure of Crystal Structure of ZBTB48 ZF10-11-C in Complex with Ciita Promoter, PDB code: 8jq0 was solved by F.D.Li, S.M.Wang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.44 / 2.90
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	126.563, 46.864, 79.047, 90, 124.89, 90
R / Rfree (%)	23.3 / 29.1

The binding sites of Zinc atom in the Crystal Structure of ZBTB48 ZF10-11-C in Complex with Ciita Promoter (pdb code 8jq0). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Crystal Structure of ZBTB48 ZF10-11-C in Complex with Ciita Promoter, PDB code: 8jq0:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Crystal Structure of ZBTB48 ZF10-11-C in Complex with Ciita Promoter


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of ZBTB48 ZF10-11-C in Complex with Ciita Promoter within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn701 b:31.1 occ:1.00 NE2 A:HIS568 2.1 37.0 1.0 NE2 A:HIS572 2.2 35.0 1.0 SG A:CYS555 2.3 39.0 1.0 SG A:CYS552 2.6 59.7 1.0 CD2 A:HIS568 2.9 40.8 1.0 CE1 A:HIS568 3.1 43.4 1.0 CD2 A:HIS572 3.2 44.8 1.0 CB A:CYS552 3.2 43.5 1.0 CE1 A:HIS572 3.3 37.8 1.0 N A:CYS555 3.5 39.9 1.0 CB A:CYS555 3.6 40.5 1.0 CB A:ILE554 3.8 50.5 1.0 CG A:HIS568 4.1 36.2 1.0 ND1 A:HIS568 4.1 37.7 1.0 CA A:CYS555 4.2 38.3 1.0 CG A:HIS572 4.3 41.4 1.0 ND1 A:HIS572 4.4 44.2 1.0 CG1 A:ILE554 4.4 33.3 1.0 C A:ILE554 4.4 35.1 1.0 CA A:ILE554 4.4 42.9 1.0 N A:ILE554 4.5 41.3 1.0 CG2 A:ILE554 4.6 45.3 1.0 CA A:CYS552 4.6 38.9 1.0 C A:CYS552 5.0 40.4 1.0

Zinc binding site 2 out of 4 in the Crystal Structure of ZBTB48 ZF10-11-C in Complex with Ciita Promoter


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of ZBTB48 ZF10-11-C in Complex with Ciita Promoter within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn702 b:37.8 occ:1.00 NE2 A:HIS596 2.2 46.9 1.0 SG A:CYS583 2.3 48.9 1.0 NE2 A:HIS600 2.4 56.0 1.0 SG A:CYS580 2.5 65.4 1.0 CD2 A:HIS596 3.1 30.4 1.0 CB A:CYS583 3.1 59.0 1.0 CD2 A:HIS600 3.2 63.2 1.0 CB A:CYS580 3.2 50.5 1.0 CE1 A:HIS596 3.2 47.4 1.0 CE1 A:HIS600 3.4 49.5 1.0 N A:CYS583 3.5 53.5 1.0 CA A:CYS583 3.8 48.0 1.0 CG A:HIS596 4.3 31.9 1.0 ND1 A:HIS596 4.3 35.3 1.0 CG A:HIS600 4.4 73.8 1.0 C A:CYS583 4.5 49.9 1.0 ND1 A:HIS600 4.5 70.7 1.0 CB A:GLU582 4.5 66.1 1.0 C A:GLU582 4.6 52.9 1.0 CA A:CYS580 4.7 43.7 1.0 N A:GLY584 4.7 45.2 1.0 CB A:TYR585 4.8 42.8 1.0 N A:GLU582 4.9 56.3 1.0 CA A:GLU582 4.9 60.6 1.0 N A:TYR585 4.9 47.7 1.0

Zinc binding site 3 out of 4 in the Crystal Structure of ZBTB48 ZF10-11-C in Complex with Ciita Promoter


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of ZBTB48 ZF10-11-C in Complex with Ciita Promoter within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn701 b:20.5 occ:1.00 NE2 D:HIS568 2.1 20.3 1.0 NE2 D:HIS572 2.1 18.7 1.0 SG D:CYS552 2.3 19.1 1.0 CB D:CYS555 2.4 11.9 1.0 CD2 D:HIS568 2.9 18.2 1.0 CD2 D:HIS572 3.0 24.4 1.0 N D:CYS555 3.0 31.7 1.0 CE1 D:HIS572 3.2 20.0 1.0 CE1 D:HIS568 3.2 26.1 1.0 CB D:CYS552 3.2 19.1 1.0 CA D:CYS555 3.3 25.1 1.0 SG D:CYS555 3.8 105.4 1.0 CG D:HIS568 4.1 17.8 1.0 CG D:HIS572 4.2 16.6 1.0 ND1 D:HIS568 4.2 17.8 1.0 N D:GLY556 4.2 40.0 1.0 ND1 D:HIS572 4.2 19.1 1.0 C D:ILE554 4.3 24.2 1.0 C D:CYS555 4.3 36.5 1.0 CB D:ILE554 4.5 24.9 1.0 OD1 D:ASN615 4.6 28.9 1.0 CA D:CYS552 4.6 24.5 1.0 CA D:ILE554 4.7 24.9 1.0 N D:ILE554 4.7 14.1 1.0 N D:LYS557 5.0 30.9 1.0

Zinc binding site 4 out of 4 in the Crystal Structure of ZBTB48 ZF10-11-C in Complex with Ciita Promoter


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Crystal Structure of ZBTB48 ZF10-11-C in Complex with Ciita Promoter within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn702 b:32.9 occ:1.00 NE2 D:HIS596 2.1 42.7 1.0 NE2 D:HIS600 2.2 55.6 1.0 SG D:CYS580 2.3 32.6 1.0 SG D:CYS583 2.4 36.8 1.0 CD2 D:HIS600 2.9 44.0 1.0 CD2 D:HIS596 3.0 36.3 1.0 CE1 D:HIS596 3.2 30.8 1.0 CB D:CYS583 3.3 30.4 1.0 CB D:CYS580 3.3 37.8 1.0 CE1 D:HIS600 3.4 48.3 1.0 N D:CYS583 3.4 39.8 1.0 CA D:CYS583 3.8 32.3 1.0 CB D:GLU582 4.1 40.3 1.0 CG D:HIS600 4.2 57.2 1.0 CG D:HIS596 4.2 32.5 1.0 ND1 D:HIS596 4.3 39.9 1.0 ND1 D:HIS600 4.3 59.3 1.0 C D:GLU582 4.5 38.6 1.0 C D:CYS583 4.5 29.2 1.0 N D:GLY584 4.6 22.8 1.0 CA D:GLU582 4.6 38.3 1.0 N D:GLU582 4.6 36.4 1.0 CA D:CYS580 4.7 42.2 1.0 SD D:MET597 4.8 64.8 1.0 CB D:TYR585 4.8 27.6 1.0 N D:TYR585 4.9 37.1 1.0

F.D.Li, S.M.Wang. Crystal Structure of ZBTB48 ZF10-11-C in Complex with Ciita Promoter To Be Published.