Zinc in PDB 8jje: Rbd of Sars-COV2 Spike Protein with ACE2 Decoy

All present enzymatic activity of Rbd of Sars-COV2 Spike Protein with ACE2 Decoy:
3.4.17.23;

The binding sites of Zinc atom in the Rbd of Sars-COV2 Spike Protein with ACE2 Decoy (pdb code 8jje). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Rbd of Sars-COV2 Spike Protein with ACE2 Decoy, PDB code: 8jje:

Zinc binding site 1 out of 1 in the Rbd of Sars-COV2 Spike Protein with ACE2 Decoy


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Rbd of Sars-COV2 Spike Protein with ACE2 Decoy within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1002 b:95.6 occ:1.00 O A:HOH1101 1.8 118.4 1.0 O1 A:SO41003 2.0 186.4 1.0 OE1 A:GLU402 2.2 98.9 1.0 NE2 A:HIS378 2.2 79.3 1.0 OE2 A:GLU402 2.2 85.5 1.0 OE2 A:GLU375 2.5 97.5 1.0 CD A:GLU402 2.6 77.6 1.0 S A:SO41003 2.7 204.6 1.0 NE2 A:HIS374 2.8 60.0 1.0 O4 A:SO41003 3.0 187.6 1.0 OH A:TYR515 3.0 93.6 1.0 CE1 A:HIS378 3.1 84.8 1.0 CD2 A:HIS378 3.1 76.4 1.0 O3 A:SO41003 3.4 204.3 1.0 CE1 A:HIS374 3.7 72.3 1.0 CD2 A:HIS374 3.8 57.6 1.0 CD A:GLU375 3.8 92.2 1.0 O2 A:SO41003 4.0 222.3 1.0 CG A:GLU402 4.1 58.1 1.0 CZ A:TYR515 4.2 83.0 1.0 ND1 A:HIS378 4.2 73.9 1.0 CG A:HIS378 4.3 66.0 1.0 OE1 A:GLU375 4.3 90.8 1.0 CE1 A:TYR515 4.6 88.7 1.0 CG A:HIS374 4.9 56.1 1.0 ND1 A:HIS374 4.9 65.1 1.0

E.Urano, Y.Itoh, T.Suzuki, T.Sasaki, J.I.Kishikawa, K.Akamatsu, Y.Higuchi, Y.Sakai, T.Okamura, S.Mitoma, F.Sugihara, A.Takada, M.Kimura, S.Nakao, M.Hirose, T.Sasaki, R.Koketsu, S.Tsuji, S.Yanagida, T.Shioda, E.Hara, S.Matoba, Y.Matsuura, Y.Kanda, H.Arase, M.Okada, J.Takagi, T.Kato, A.Hoshino, Y.Yasutomi, A.Saito, T.Okamoto. An Inhaled ACE2 Decoy Confers Protection Against Sars-Cov-2 Infection in Preclinical Models. Sci Transl Med V. 15 I2623 2023.
ISSN: ESSN 1946-6242
PubMed: 37647387
DOI: 10.1126/SCITRANSLMED.ADI2623