Zinc in PDB 8d8o: Cryo-Em Structure of Substrate Unbound Papp-A

All present enzymatic activity of Cryo-Em Structure of Substrate Unbound Papp-A:
3.4.24.79;

The binding sites of Zinc atom in the Cryo-Em Structure of Substrate Unbound Papp-A (pdb code 8d8o). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Cryo-Em Structure of Substrate Unbound Papp-A, PDB code: 8d8o:

Zinc binding site 1 out of 1 in the Cryo-Em Structure of Substrate Unbound Papp-A


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of Substrate Unbound Papp-A within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1601 b:56.6 occ:1.00 NE2 B:HIS492 2.3 28.3 1.0 NE2 B:HIS482 2.3 17.5 1.0 NE2 B:HIS486 2.3 17.3 1.0 CD2 B:HIS486 2.7 17.1 1.0 CE1 B:HIS492 2.9 30.5 1.0 CD2 B:HIS482 2.9 17.1 1.0 CD1 B:LEU445 3.3 64.5 1.0 CE1 B:HIS482 3.5 19.8 1.0 CE1 B:HIS486 3.5 16.6 1.0 CD2 B:HIS492 3.5 28.5 1.0 CG B:HIS486 4.0 12.2 1.0 ND1 B:HIS492 4.1 32.2 1.0 OH B:TYR558 4.2 66.1 1.0 CG B:HIS482 4.2 12.0 1.0 ND1 B:HIS486 4.3 14.6 1.0 ND1 B:HIS482 4.4 17.3 1.0 CG B:HIS492 4.5 31.5 1.0 CZ B:TYR558 4.7 64.1 1.0 CG B:LEU445 4.7 67.2 1.0 O B:GLY447 4.9 39.9 1.0

R.A.Judge, J.Sridar, K.Tunyasunvunakool, R.Jain, J.C.K.Wang, C.Ouch, J.Xu, A.Mafi, A.H.Nile, C.Remarcik, C.L.Smith, C.Ghosh, C.Xu, V.Stoll, J.Jumper, A.H.Singh, D.Eaton, Q.Hao. Structure of the Papp-ABP5 Complex Reveals Mechanism of Substrate Recognition Nat Commun V. 13 5500 2022.
ISSN: ESSN 2041-1723
PubMed: 36127359
DOI: 10.1038/S41467-022-33175-2