Zinc in PDB 7vuw: Bovine Heart Cytochrome C Oxidase in the Cyanide-Bound Fully Oxidized State at 50 K

All present enzymatic activity of Bovine Heart Cytochrome C Oxidase in the Cyanide-Bound Fully Oxidized State at 50 K:
7.1.1.9;

The structure of Bovine Heart Cytochrome C Oxidase in the Cyanide-Bound Fully Oxidized State at 50 K, PDB code: 7vuw was solved by A.Shimada, T.Tsukihara, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.92 / 1.60
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	182.076, 204.481, 177.68, 90, 90, 90
R / Rfree (%)	15.4 / 17.5

The structure of Bovine Heart Cytochrome C Oxidase in the Cyanide-Bound Fully Oxidized State at 50 K also contains other interesting chemical elements:

Copper	(Cu)	6 atoms
Iron	(Fe)	4 atoms
Magnesium	(Mg)	2 atoms
Sodium	(Na)	2 atoms

The binding sites of Zinc atom in the Bovine Heart Cytochrome C Oxidase in the Cyanide-Bound Fully Oxidized State at 50 K (pdb code 7vuw). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Bovine Heart Cytochrome C Oxidase in the Cyanide-Bound Fully Oxidized State at 50 K, PDB code: 7vuw:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Bovine Heart Cytochrome C Oxidase in the Cyanide-Bound Fully Oxidized State at 50 K


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Bovine Heart Cytochrome C Oxidase in the Cyanide-Bound Fully Oxidized State at 50 K within 5.0Å range: probe atom residue distance (Å) B Occ F:Zn101 b:25.4 occ:1.00 SG F:CYS62 2.3 26.1 1.0 SG F:CYS82 2.3 26.0 1.0 SG F:CYS60 2.3 26.7 1.0 SG F:CYS85 2.4 28.3 1.0 CB F:CYS82 3.2 24.3 1.0 CB F:CYS60 3.3 28.3 1.0 CB F:CYS62 3.3 25.3 1.0 CB F:CYS85 3.4 26.9 1.0 CA F:CYS62 3.6 26.9 1.0 N F:CYS85 3.7 25.6 1.0 CA F:CYS85 4.1 26.2 1.0 N F:CYS62 4.1 26.9 1.0 O F:CYS60 4.4 24.6 1.0 C F:CYS60 4.4 28.2 1.0 CB F:SER84 4.4 27.6 1.0 CA F:CYS60 4.4 28.8 1.0 O F:HOH223 4.5 38.3 1.0 CA F:CYS82 4.7 24.6 1.0 OG F:SER84 4.7 34.9 1.0 C F:SER84 4.7 32.5 1.0 C F:CYS85 4.8 26.9 1.0 CG2 F:THR87 4.9 42.3 1.0 CB F:ILE70 4.9 23.2 1.0 C F:ILE61 4.9 29.5 1.0 C F:CYS62 4.9 29.7 1.0 N F:GLY86 4.9 26.4 1.0 CG1 F:ILE70 4.9 22.9 1.0 N F:SER84 4.9 26.8 1.0 CA F:SER84 5.0 27.1 1.0

Zinc binding site 2 out of 2 in the Bovine Heart Cytochrome C Oxidase in the Cyanide-Bound Fully Oxidized State at 50 K


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Bovine Heart Cytochrome C Oxidase in the Cyanide-Bound Fully Oxidized State at 50 K within 5.0Å range: probe atom residue distance (Å) B Occ S:Zn101 b:25.4 occ:1.00 SG S:CYS62 2.3 28.3 1.0 SG S:CYS82 2.3 28.1 1.0 SG S:CYS60 2.3 27.4 1.0 SG S:CYS85 2.3 28.4 1.0 CB S:CYS82 3.2 26.9 1.0 CB S:CYS62 3.3 27.6 1.0 CB S:CYS60 3.3 26.4 1.0 CB S:CYS85 3.4 27.3 1.0 CA S:CYS62 3.6 27.0 1.0 N S:CYS85 3.7 29.1 1.0 CA S:CYS85 4.1 29.6 1.0 N S:CYS62 4.2 25.8 1.0 C S:CYS60 4.4 26.3 1.0 O S:CYS60 4.4 24.6 1.0 CB S:SER84 4.5 30.8 1.0 CA S:CYS60 4.5 25.7 1.0 CG2 S:THR87 4.5 39.9 1.0 O S:HOH239 4.6 38.2 1.0 OG S:SER84 4.6 37.2 1.0 CA S:CYS82 4.6 26.9 1.0 C S:SER84 4.7 30.2 1.0 C S:CYS85 4.8 30.6 1.0 C S:ILE61 4.9 27.6 1.0 CB S:ILE70 4.9 22.9 1.0 N S:GLY86 4.9 27.4 1.0 CA S:SER84 4.9 27.9 1.0 N S:SER84 5.0 28.9 1.0 CG1 S:ILE70 5.0 24.5 1.0 C S:CYS62 5.0 33.6 1.0

A.Shimada, T.Tsukihara. Bovine Cytochrome C Oxidese in Cn-Bound Fully Oxidized State at 50 K To Be Published.