Zinc in PDB 7vib: Crystal Structure of Human ACE2 and Gx/P2V Rbd

All present enzymatic activity of Crystal Structure of Human ACE2 and Gx/P2V Rbd:
3.4.17.23;

The structure of Crystal Structure of Human ACE2 and Gx/P2V Rbd, PDB code: 7vib was solved by Y.Guo, W.Cao, N.Jia, W.Wang, S.Yuan, Y.Wang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.29 / 3.20
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	81.672, 120.15, 107.885, 90, 96.61, 90
R / Rfree (%)	20.4 / 25.8

The binding sites of Zinc atom in the Crystal Structure of Human ACE2 and Gx/P2V Rbd (pdb code 7vib). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Human ACE2 and Gx/P2V Rbd, PDB code: 7vib:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Human ACE2 and Gx/P2V Rbd


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Human ACE2 and Gx/P2V Rbd within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1001 b:84.9 occ:1.00 OE2 A:GLU402 1.8 62.5 1.0 NE2 A:HIS378 2.3 59.7 1.0 NE2 A:HIS374 2.3 59.3 1.0 CD A:GLU402 2.6 60.6 1.0 CD2 A:HIS374 2.7 60.6 1.0 OE1 A:GLU402 2.8 62.9 1.0 CD2 A:HIS378 3.2 58.6 1.0 CE1 A:HIS378 3.4 57.0 1.0 OE2 A:GLU375 3.5 64.0 1.0 CE1 A:HIS374 3.6 58.5 1.0 CG A:GLU402 4.0 58.3 1.0 CG A:HIS374 4.0 59.3 1.0 OE1 A:GLU375 4.2 62.8 1.0 CD A:GLU375 4.2 63.7 1.0 CG A:HIS378 4.4 56.5 1.0 ND1 A:HIS374 4.4 58.7 1.0 ND1 A:HIS378 4.4 56.1 1.0 CB A:GLU402 4.9 56.5 1.0 CA A:GLU402 4.9 55.2 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Human ACE2 and Gx/P2V Rbd


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Human ACE2 and Gx/P2V Rbd within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn1001 b:68.7 occ:1.00 OE2 C:GLU402 2.0 50.6 1.0 NE2 C:HIS378 2.4 46.8 1.0 NE2 C:HIS374 2.4 45.9 1.0 CD C:GLU402 2.7 48.6 1.0 OE1 C:GLU402 2.9 47.4 1.0 CD2 C:HIS374 3.1 44.5 1.0 CD2 C:HIS378 3.2 45.5 1.0 OE2 C:GLU375 3.3 44.4 1.0 CE1 C:HIS378 3.4 46.2 1.0 CE1 C:HIS374 3.6 44.6 1.0 CG C:GLU402 4.1 47.6 1.0 CD C:GLU375 4.2 43.3 1.0 OE1 C:GLU375 4.3 43.4 1.0 CG C:HIS374 4.4 43.0 1.0 CG C:HIS378 4.4 44.6 1.0 ND1 C:HIS378 4.5 45.0 1.0 ND1 C:HIS374 4.6 43.2 1.0 CB C:GLU402 4.9 45.9 1.0 CA C:GLU402 5.0 46.4 1.0

Y.Guo, W.Cao, N.Jia, W.Wang, S.Yuan, Y.Wang. Crystal Structure of Human ACE2 and Gx/P2V Rbd To Be Published.