Zinc in PDB 7vh1: Cryo-Em Structure of Machupo Virus Dimeric L-Z Complex

All present enzymatic activity of Cryo-Em Structure of Machupo Virus Dimeric L-Z Complex:
2.7.7.48;

The binding sites of Zinc atom in the Cryo-Em Structure of Machupo Virus Dimeric L-Z Complex (pdb code 7vh1). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Cryo-Em Structure of Machupo Virus Dimeric L-Z Complex, PDB code: 7vh1:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Cryo-Em Structure of Machupo Virus Dimeric L-Z Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of Machupo Virus Dimeric L-Z Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn101 b:95.9 occ:1.00 SG B:CYS42 2.4 59.3 1.0 SG B:CYS61 2.4 97.9 1.0 SG B:CYS58 2.5 95.4 1.0 SG B:CYS41 2.5 65.0 1.0 CB B:CYS42 2.6 59.3 1.0 CB B:CYS61 2.9 97.9 1.0 N B:CYS42 3.6 59.3 1.0 CA B:CYS42 3.7 59.3 1.0 CB B:CYS58 4.0 95.4 1.0 N B:CYS61 4.0 97.9 1.0 CA B:CYS61 4.0 97.9 1.0 CB B:CYS41 4.1 65.0 1.0 O A:SER687 4.2 57.1 1.0 C B:CYS41 4.6 65.0 1.0 N B:CYS58 4.6 95.4 1.0 O A:SER686 4.6 60.4 1.0 C B:CYS42 4.8 59.3 1.0 CA B:CYS58 4.8 95.4 1.0 CB B:CYS39 4.9 79.2 1.0 CA B:CYS41 4.9 65.0 1.0

Zinc binding site 2 out of 2 in the Cryo-Em Structure of Machupo Virus Dimeric L-Z Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryo-Em Structure of Machupo Virus Dimeric L-Z Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn102 b:135.3 occ:1.00 NE2 B:HIS55 2.2 106.2 1.0 CE1 B:HIS55 2.4 106.2 1.0 SG B:CYS72 2.5 112.9 1.0 CB B:ILE74 2.8 109.2 1.0 N B:CYS75 2.9 113.5 1.0 SG B:CYS75 3.2 113.5 1.0 CD2 B:HIS55 3.2 106.2 1.0 ND1 B:HIS55 3.4 106.2 1.0 CA B:ILE74 3.4 109.2 1.0 N B:ILE74 3.4 109.2 1.0 C B:ILE74 3.5 109.2 1.0 CB B:CYS72 3.5 112.9 1.0 CG2 B:ILE74 3.6 109.2 1.0 CB B:CYS75 3.7 113.5 1.0 CG1 B:ILE74 3.8 109.2 1.0 CG B:HIS55 3.8 106.2 1.0 CA B:CYS75 3.9 113.5 1.0 O B:ILE74 4.6 109.2 1.0 N B:HIS73 4.6 109.3 1.0 C B:HIS73 4.7 109.3 1.0 N B:TRP76 4.8 101.2 1.0 C B:CYS75 4.8 113.5 1.0 CA B:CYS72 4.9 112.9 1.0

J.Ma, S.Zhang, X.Zhang. Structure of Machupo Virus Polymerase in Complex with Matrix Protein Z To Be Published.