Zinc in PDB 7txv: Cyanophycin Synthetase 1 From Synechocystis Sp. UTEX2470 E82Q with Atp and 16X(Asp-Arg)

All present enzymatic activity of Cyanophycin Synthetase 1 From Synechocystis Sp. UTEX2470 E82Q with Atp and 16X(Asp-Arg):
6.3.2.29; 6.3.2.30;

The structure of Cyanophycin Synthetase 1 From Synechocystis Sp. UTEX2470 E82Q with Atp and 16X(Asp-Arg) also contains other interesting chemical elements:

Magnesium

(Mg)

16 atoms

The binding sites of Zinc atom in the Cyanophycin Synthetase 1 From Synechocystis Sp. UTEX2470 E82Q with Atp and 16X(Asp-Arg) (pdb code 7txv). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Cyanophycin Synthetase 1 From Synechocystis Sp. UTEX2470 E82Q with Atp and 16X(Asp-Arg), PDB code: 7txv:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Cyanophycin Synthetase 1 From Synechocystis Sp. UTEX2470 E82Q with Atp and 16X(Asp-Arg)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cyanophycin Synthetase 1 From Synechocystis Sp. UTEX2470 E82Q with Atp and 16X(Asp-Arg) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn905 b:87.6 occ:1.00 NE2 A:HIS83 2.0 73.1 1.0 NE2 A:HIS79 2.0 76.6 1.0 SG A:CYS59 2.3 81.1 1.0 CD2 A:HIS79 2.7 76.6 1.0 CD2 A:HIS83 2.9 73.1 1.0 CE1 A:HIS83 3.0 73.1 1.0 CE1 A:HIS79 3.2 76.6 1.0 CB A:CYS59 3.5 81.1 1.0 N I:7ID6 3.6 71.2 1.0 O I:7ID4 3.6 71.2 1.0 CG A:HIS79 4.0 76.6 1.0 CD1 A:PHE67 4.0 89.0 1.0 CG A:HIS83 4.0 73.1 1.0 ND1 A:HIS83 4.1 73.1 1.0 ND1 A:HIS79 4.1 76.6 1.0 CE1 A:PHE67 4.1 89.0 1.0 C I:7ID5 4.3 71.2 1.0 CA A:CYS59 4.3 81.1 1.0 C I:7ID4 4.4 71.2 1.0 CB I:7ID6 4.5 71.2 1.0 OE1 A:GLN82 4.5 66.9 1.0 CA I:7ID6 4.5 71.2 1.0 NE2 A:GLN82 4.6 66.9 1.0 O A:HIS79 4.6 76.6 1.0 N I:7ID5 4.7 71.2 1.0 CA I:7ID5 4.7 71.2 1.0 O I:7ID6 4.9 71.2 1.0 CD A:GLN82 4.9 66.9 1.0 CG A:PHE67 5.0 89.0 1.0

Zinc binding site 2 out of 4 in the Cyanophycin Synthetase 1 From Synechocystis Sp. UTEX2470 E82Q with Atp and 16X(Asp-Arg)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cyanophycin Synthetase 1 From Synechocystis Sp. UTEX2470 E82Q with Atp and 16X(Asp-Arg) within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn905 b:96.3 occ:1.00 NE2 B:HIS83 2.0 78.0 1.0 NE2 B:HIS79 2.0 82.8 1.0 SG B:CYS59 2.3 87.6 1.0 CD2 B:HIS79 2.7 82.8 1.0 CD2 B:HIS83 2.9 78.0 1.0 CE1 B:HIS83 3.0 78.0 1.0 CE1 B:HIS79 3.2 82.8 1.0 CB B:CYS59 3.5 87.6 1.0 N J:7ID6 3.6 73.8 1.0 O J:7ID4 3.6 73.8 1.0 CG B:HIS79 4.0 82.8 1.0 CD1 B:PHE67 4.0 94.1 1.0 CG B:HIS83 4.0 78.0 1.0 ND1 B:HIS83 4.1 78.0 1.0 ND1 B:HIS79 4.1 82.8 1.0 CE1 B:PHE67 4.1 94.1 1.0 C J:7ID5 4.3 73.8 1.0 CA B:CYS59 4.3 87.6 1.0 C J:7ID4 4.4 73.8 1.0 CB J:7ID6 4.5 73.8 1.0 OE1 B:GLN82 4.5 71.3 1.0 CA J:7ID6 4.5 73.8 1.0 NE2 B:GLN82 4.6 71.3 1.0 O B:HIS79 4.6 82.8 1.0 N J:7ID5 4.7 73.8 1.0 CA J:7ID5 4.7 73.8 1.0 O J:7ID6 4.9 73.8 1.0 CD B:GLN82 4.9 71.3 1.0 CG B:PHE67 5.0 94.1 1.0

Zinc binding site 3 out of 4 in the Cyanophycin Synthetase 1 From Synechocystis Sp. UTEX2470 E82Q with Atp and 16X(Asp-Arg)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Cyanophycin Synthetase 1 From Synechocystis Sp. UTEX2470 E82Q with Atp and 16X(Asp-Arg) within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn905 b:91.9 occ:1.00 NE2 C:HIS83 2.0 75.8 1.0 NE2 C:HIS79 2.0 80.5 1.0 SG C:CYS59 2.3 84.8 1.0 CD2 C:HIS79 2.7 80.5 1.0 CD2 C:HIS83 2.9 75.8 1.0 CE1 C:HIS83 3.0 75.8 1.0 CE1 C:HIS79 3.2 80.5 1.0 CB C:CYS59 3.5 84.8 1.0 N K:7ID6 3.6 72.4 1.0 O K:7ID4 3.6 72.4 1.0 CG C:HIS79 4.0 80.5 1.0 CD1 C:PHE67 4.0 92.8 1.0 CG C:HIS83 4.0 75.8 1.0 ND1 C:HIS83 4.1 75.8 1.0 ND1 C:HIS79 4.1 80.5 1.0 CE1 C:PHE67 4.1 92.8 1.0 C K:7ID5 4.3 72.4 1.0 CA C:CYS59 4.3 84.8 1.0 C K:7ID4 4.4 72.4 1.0 CB K:7ID6 4.5 72.4 1.0 OE1 C:GLN82 4.5 69.0 1.0 CA K:7ID6 4.5 72.4 1.0 NE2 C:GLN82 4.6 69.0 1.0 O C:HIS79 4.6 80.5 1.0 N K:7ID5 4.7 72.4 1.0 CA K:7ID5 4.7 72.4 1.0 O K:7ID6 4.9 72.4 1.0 CD C:GLN82 4.9 69.0 1.0 CG C:PHE67 5.0 92.8 1.0

Zinc binding site 4 out of 4 in the Cyanophycin Synthetase 1 From Synechocystis Sp. UTEX2470 E82Q with Atp and 16X(Asp-Arg)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Cyanophycin Synthetase 1 From Synechocystis Sp. UTEX2470 E82Q with Atp and 16X(Asp-Arg) within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn905 b:95.2 occ:1.00 NE2 D:HIS83 2.0 76.4 1.0 NE2 D:HIS79 2.0 81.3 1.0 SG D:CYS59 2.3 85.5 1.0 CD2 D:HIS79 2.7 81.3 1.0 CD2 D:HIS83 2.9 76.4 1.0 CE1 D:HIS83 3.0 76.4 1.0 CE1 D:HIS79 3.2 81.3 1.0 CB D:CYS59 3.5 85.5 1.0 N L:7ID6 3.6 73.1 1.0 O L:7ID4 3.6 73.1 1.0 CG D:HIS79 4.0 81.3 1.0 CD1 D:PHE67 4.0 92.7 1.0 CG D:HIS83 4.0 76.4 1.0 ND1 D:HIS83 4.1 76.4 1.0 ND1 D:HIS79 4.1 81.3 1.0 CE1 D:PHE67 4.1 92.7 1.0 C L:7ID5 4.3 73.1 1.0 CA D:CYS59 4.3 85.5 1.0 C L:7ID4 4.4 73.1 1.0 CB L:7ID6 4.5 73.1 1.0 OE1 D:GLN82 4.5 69.7 1.0 CA L:7ID6 4.5 73.1 1.0 NE2 D:GLN82 4.6 69.7 1.0 O D:HIS79 4.6 81.3 1.0 N L:7ID5 4.7 73.1 1.0 CA L:7ID5 4.7 73.1 1.0 O L:7ID6 4.9 73.1 1.0 CD D:GLN82 4.9 69.7 1.0 CG D:PHE67 5.0 92.7 1.0

I.Sharon, S.Pinus, M.Grogg, N.Moitessier, D.Hilvert, T.M.Schmeing. A Cryptic Third Active Site in Cyanophycin Synthetase Creates Primers For Polymerization Nat Commun V. 13 3923 2022.
ISSN: ESSN 2041-1723
DOI: 10.1038/S41467-022-31542-7