Zinc in PDB 7tv4: Crystal Structure of Nemo Cozi in Complex with Hoip NZF1 and Linear Diubiquitin

All present enzymatic activity of Crystal Structure of Nemo Cozi in Complex with Hoip NZF1 and Linear Diubiquitin:
2.3.2.31;

The structure of Crystal Structure of Nemo Cozi in Complex with Hoip NZF1 and Linear Diubiquitin, PDB code: 7tv4 was solved by S.Rahighi, M.Iyer, H.Oveisi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	56.01 / 4.20
Space group	P 2 21 21
Cell size a, b, c (Å), α, β, γ (°)	55.95, 69.56, 180.05, 90, 90, 90
R / Rfree (%)	22.2 / 28.6

The binding sites of Zinc atom in the Crystal Structure of Nemo Cozi in Complex with Hoip NZF1 and Linear Diubiquitin (pdb code 7tv4). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Nemo Cozi in Complex with Hoip NZF1 and Linear Diubiquitin, PDB code: 7tv4:

Zinc binding site 1 out of 1 in the Crystal Structure of Nemo Cozi in Complex with Hoip NZF1 and Linear Diubiquitin


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Nemo Cozi in Complex with Hoip NZF1 and Linear Diubiquitin within 5.0Å range: probe atom residue distance (Å) B Occ K:Zn401 b:87.1 occ:1.00 SG K:CYS373 2.3 89.5 1.0 SG K:CYS370 2.3 96.2 1.0 SG K:CYS359 2.3 87.4 1.0 SG K:CYS356 2.3 94.1 1.0 CB K:CYS356 3.2 93.0 1.0 CB K:CYS373 3.3 90.5 1.0 CB K:CYS370 3.3 94.8 1.0 CB K:CYS359 3.5 87.9 1.0 OG K:SER358 3.6 103.7 1.0 N K:CYS359 3.9 94.0 1.0 N K:CYS373 4.0 90.6 1.0 CA K:CYS359 4.2 89.8 1.0 CA K:CYS373 4.3 91.0 1.0 CB K:ILE372 4.4 102.0 1.0 CA K:CYS356 4.5 94.5 1.0 O K:CYS356 4.5 88.6 1.0 C K:CYS359 4.7 90.2 1.0 CG1 K:ILE372 4.7 101.7 1.0 CA K:CYS370 4.7 91.0 1.0 CB K:SER358 4.8 96.5 1.0 CB K:PHE361 4.8 103.1 1.0 C K:CYS356 4.8 90.3 1.0 C K:ILE372 4.9 91.7 1.0 N K:THR360 5.0 96.0 1.0 C K:SER358 5.0 93.8 1.0

S.Rahighi, M.Iyer, H.Oveisi, S.Nasser, V.Duong. Structural Basis For the Simultaneous Recognition of Nemo and Acceptor Ubiquitin By the Hoip NZF1 Domain. Sci Rep V. 12 12241 2022.
ISSN: ESSN 2045-2322
PubMed: 35851409
DOI: 10.1038/S41598-022-16193-4