Zinc in PDB 7rlk: Wallaby Ttr

The structure of Wallaby Ttr, PDB code: 7rlk was solved by D.G.D-Souza, S.J.Richardson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	37.24 / 2.69
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	66.516, 112.152, 245.281, 90, 90, 90
R / Rfree (%)	18.8 / 21.7

The binding sites of Zinc atom in the Wallaby Ttr (pdb code 7rlk). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 8 binding sites of Zinc where determined in the Wallaby Ttr, PDB code: 7rlk:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6; 7; 8;

Zinc binding site 1 out of 8 in the Wallaby Ttr


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Wallaby Ttr within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:101.8 occ:1.00 NZ B:LYS70 3.3 56.6 1.0 NZ A:LYS70 3.4 53.6 1.0 NE1 A:TRP41 3.9 60.4 1.0 NE1 B:TRP41 3.9 48.4 1.0 CD1 A:TRP41 4.0 60.8 1.0 CD1 B:TRP41 4.0 49.4 1.0 CE B:LYS70 4.8 55.3 1.0 CE A:LYS70 4.9 52.3 1.0

Zinc binding site 2 out of 8 in the Wallaby Ttr


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Wallaby Ttr within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn202 b:121.8 occ:1.00 NE2 A:HIS102 2.1 85.4 1.0 OD2 A:ASP61 2.2 86.0 1.0 NE2 A:HIS104 2.4 75.2 1.0 OD1 A:ASP61 2.8 85.5 1.0 CG A:ASP61 2.8 86.6 1.0 CD2 A:HIS102 3.0 87.5 1.0 CE1 A:HIS102 3.1 85.4 1.0 CD2 A:HIS104 3.3 70.7 1.0 CE1 A:HIS104 3.4 73.7 1.0 ND1 A:HIS102 4.2 86.3 1.0 CB A:ASP61 4.2 88.9 1.0 CG A:HIS102 4.2 88.6 1.0 ND1 A:HIS104 4.5 69.2 1.0 CG A:HIS104 4.5 68.2 1.0

Zinc binding site 3 out of 8 in the Wallaby Ttr


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Wallaby Ttr within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn201 b:95.7 occ:1.00 NZ D:LYS70 3.2 57.7 1.0 NZ C:LYS70 3.3 50.5 1.0 NE1 D:TRP41 3.8 60.3 1.0 NE1 C:TRP41 3.9 51.1 1.0 CD1 D:TRP41 4.1 61.7 1.0 CD1 C:TRP41 4.1 52.2 1.0 CE D:LYS70 4.7 55.6 1.0 CE C:LYS70 4.8 48.7 1.0

Zinc binding site 4 out of 8 in the Wallaby Ttr


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Wallaby Ttr within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn202 b:109.8 occ:1.00 OD2 C:ASP61 2.1 92.1 1.0 NE2 C:HIS102 2.2 74.0 1.0 NE2 C:HIS104 2.4 75.5 1.0 CG C:ASP61 2.7 90.5 1.0 OD1 C:ASP61 2.8 85.9 1.0 CD2 C:HIS102 3.1 76.4 1.0 CE1 C:HIS102 3.2 73.5 1.0 CE1 C:HIS104 3.4 76.4 1.0 CD2 C:HIS104 3.4 70.8 1.0 CB C:ASP61 4.1 93.6 1.0 ND1 C:HIS102 4.3 73.9 1.0 CG C:HIS102 4.3 77.1 1.0 ND1 C:HIS104 4.5 72.8 1.0 CG C:HIS104 4.5 68.9 1.0

Zinc binding site 5 out of 8 in the Wallaby Ttr


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Wallaby Ttr within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn201 b:73.4 occ:1.00 OD2 D:ASP61 2.0 67.8 1.0 NE2 D:HIS102 2.0 62.1 1.0 NE2 D:HIS104 2.3 62.4 1.0 OD1 D:ASP61 2.4 61.3 1.0 CG D:ASP61 2.5 66.3 1.0 CE1 D:HIS102 3.0 60.8 1.0 CD2 D:HIS102 3.0 64.0 1.0 CD2 D:HIS104 3.2 58.4 1.0 CE1 D:HIS104 3.3 62.3 1.0 CB D:ASP61 3.9 70.5 1.0 CG D:PRO125 4.0 55.1 1.0 ND1 D:HIS102 4.1 61.1 1.0 CG D:HIS102 4.1 63.1 1.0 CG D:HIS104 4.4 55.8 1.0 ND1 D:HIS104 4.4 58.8 1.0 CB D:PRO125 4.6 57.0 1.0 CB D:PRO11 4.8 69.7 1.0

Zinc binding site 6 out of 8 in the Wallaby Ttr


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of Wallaby Ttr within 5.0Å range: probe atom residue distance (Å) B Occ E:Zn201 b:118.2 occ:1.00 NE2 E:HIS102 2.3 92.7 1.0 OD2 E:ASP61 2.4 99.2 1.0 NE2 E:HIS104 2.5 84.9 1.0 CG E:ASP61 3.1 96.2 1.0 OD1 E:ASP61 3.1 92.6 1.0 CD2 E:HIS102 3.2 93.9 1.0 CE1 E:HIS104 3.4 84.4 1.0 CE1 E:HIS102 3.4 92.2 1.0 CD2 E:HIS104 3.5 80.0 1.0 CG E:HIS102 4.4 94.9 1.0 CB E:ASP61 4.4 98.1 1.0 ND1 E:HIS102 4.5 92.8 1.0 ND1 E:HIS104 4.5 80.8 1.0 CG E:HIS104 4.6 77.8 1.0

Zinc binding site 7 out of 8 in the Wallaby Ttr


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 7 of Wallaby Ttr within 5.0Å range: probe atom residue distance (Å) B Occ E:Zn202 b:94.1 occ:1.00 NZ E:LYS70 3.2 51.6 1.0 NE1 E:TRP41 3.7 55.0 1.0 NZ F:LYS70 3.9 52.1 1.0 CD1 E:TRP41 4.0 55.3 1.0 NE1 F:TRP41 4.1 51.7 1.0 CD1 F:TRP41 4.3 51.7 1.0 CE E:LYS70 4.6 50.4 1.0 CE2 E:TRP41 5.0 54.5 1.0

Zinc binding site 8 out of 8 in the Wallaby Ttr


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 8 of Wallaby Ttr within 5.0Å range: probe atom residue distance (Å) B Occ F:Zn201 b:119.0 occ:1.00 NE2 F:HIS102 2.1 84.0 1.0 OD2 F:ASP61 2.5 87.2 1.0 NE2 F:HIS104 2.5 84.2 1.0 CD2 F:HIS102 2.9 87.9 1.0 OD1 F:ASP61 2.9 81.4 1.0 CG F:ASP61 3.0 84.8 1.0 CE1 F:HIS102 3.2 80.0 1.0 CD2 F:HIS104 3.4 79.8 1.0 CE1 F:HIS104 3.5 83.9 1.0 CG F:HIS102 4.1 87.5 1.0 ND1 F:HIS102 4.2 81.6 1.0 CB F:ASP61 4.3 85.3 1.0 ND2 F:ASN124 4.5 82.3 1.0 CG F:HIS104 4.6 77.9 1.0 ND1 F:HIS104 4.6 82.0 1.0

D.G.D-Souza, S.J.Richardson. Structural and Amyloidogenic Comparisons of Human and Wallaby Transthyretins: Implications For Amyloidosis? To Be Published.