Atomistry » Zinc » PDB 7ofs-8rnt » 7ozv
Atomistry »
  Zinc »
    PDB 7ofs-8rnt »
      7ozv »

Zinc in PDB 7ozv: Sars-Cov-2 Rdrp with Molnupiravir/ Nhc in the Template Strand Base- Paired with G

Zinc Binding Sites:

The binding sites of Zinc atom in the Sars-Cov-2 Rdrp with Molnupiravir/ Nhc in the Template Strand Base- Paired with G (pdb code 7ozv). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Sars-Cov-2 Rdrp with Molnupiravir/ Nhc in the Template Strand Base- Paired with G, PDB code: 7ozv:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 7ozv

Go back to Zinc Binding Sites List in 7ozv
Zinc binding site 1 out of 2 in the Sars-Cov-2 Rdrp with Molnupiravir/ Nhc in the Template Strand Base- Paired with G


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Sars-Cov-2 Rdrp with Molnupiravir/ Nhc in the Template Strand Base- Paired with G within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn2000

b:75.6
occ:1.00
ND1 A:HIS295 2.1 51.9 1.0
SG A:CYS301 2.3 55.9 1.0
SG A:CYS306 2.3 53.0 1.0
SG A:CYS310 2.3 49.2 1.0
CE1 A:HIS295 3.0 51.9 1.0
CG A:HIS295 3.1 51.9 1.0
CB A:CYS301 3.3 55.9 1.0
CA A:CYS301 3.4 55.9 1.0
CB A:HIS295 3.5 51.9 1.0
O A:CYS306 3.6 53.0 1.0
CB A:CYS306 3.6 53.0 1.0
CB A:CYS310 3.8 49.2 1.0
C A:CYS306 4.0 53.0 1.0
NE2 A:HIS295 4.1 51.9 1.0
N A:HIS295 4.1 51.9 1.0
CD2 A:HIS295 4.2 51.9 1.0
N A:CYS301 4.2 55.9 1.0
CA A:CYS306 4.3 53.0 1.0
CA A:HIS295 4.4 51.9 1.0
N A:LEU302 4.5 57.2 1.0
C A:CYS301 4.5 55.9 1.0
O A:THR293 4.5 52.7 1.0
N A:ILE307 4.8 50.0 1.0
C A:ASN300 4.8 56.0 1.0
O A:ASN300 4.9 56.0 1.0
O A:HIS295 4.9 51.9 1.0

Zinc binding site 2 out of 2 in 7ozv

Go back to Zinc Binding Sites List in 7ozv
Zinc binding site 2 out of 2 in the Sars-Cov-2 Rdrp with Molnupiravir/ Nhc in the Template Strand Base- Paired with G


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Sars-Cov-2 Rdrp with Molnupiravir/ Nhc in the Template Strand Base- Paired with G within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn2001

b:72.5
occ:1.00
SG A:CYS487 2.2 62.6 1.0
SG A:CYS646 2.3 60.6 1.0
SG A:CYS645 2.3 65.9 1.0
ND1 A:HIS642 2.3 59.4 1.0
CB A:CYS487 3.0 62.6 1.0
CE1 A:HIS642 3.1 59.4 1.0
CG A:HIS642 3.3 59.4 1.0
N A:CYS487 3.3 62.6 1.0
CB A:CYS645 3.6 65.9 1.0
CB A:CYS646 3.6 60.6 1.0
CB A:HIS642 3.7 59.4 1.0
CA A:CYS487 3.7 62.6 1.0
N A:CYS646 4.0 60.6 1.0
C A:CYS645 4.1 65.9 1.0
NE2 A:HIS642 4.3 59.4 1.0
CA A:CYS646 4.3 60.6 1.0
CE1 A:PHE571 4.3 55.9 1.0
CD2 A:HIS642 4.4 59.4 1.0
C A:GLY486 4.4 62.2 1.0
CA A:CYS645 4.4 65.9 1.0
O A:CYS645 4.5 65.9 1.0
CA A:HIS642 4.6 59.4 1.0
CD1 A:PHE571 4.7 55.9 1.0
CA A:GLY486 4.7 62.2 1.0
CE A:LYS532 5.0 56.0 1.0

Reference:

F.Kabinger, C.Stiller, J.Schmitzova, C.Dienemann, G.Kokic, H.S.Hillen, C.Hobartner, P.Cramer. Mechanism of Molnupiravir-Induced Sars-Cov-2 Mutagenesis Nat.Chem.Biol. 2021.
ISSN: ESSN 1552-4469
DOI: 10.1038/S41594-021-00651-0
Page generated: Sun Aug 22 09:53:06 2021

Last articles

Zn in 7RRP
Zn in 7OKY
Zn in 7OL0
Zn in 7OKX
Zn in 7ONB
Zn in 7RSF
Zn in 7OUF
Zn in 7OUG
Zn in 7OUH
Zn in 7RGN
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy