Atomistry » Zinc » PDB 7oie-7oru » 7oni
Atomistry »
  Zinc »
    PDB 7oie-7oru »
      7oni »

Zinc in PDB 7oni: Structure of Neddylated CUL5 C-Terminal Region-RBX2-ARIH2*

Enzymatic activity of Structure of Neddylated CUL5 C-Terminal Region-RBX2-ARIH2*

All present enzymatic activity of Structure of Neddylated CUL5 C-Terminal Region-RBX2-ARIH2*:
2.3.2.31;

Zinc Binding Sites:

The binding sites of Zinc atom in the Structure of Neddylated CUL5 C-Terminal Region-RBX2-ARIH2* (pdb code 7oni). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 7 binding sites of Zinc where determined in the Structure of Neddylated CUL5 C-Terminal Region-RBX2-ARIH2*, PDB code: 7oni:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6; 7;

Zinc binding site 1 out of 7 in 7oni

Go back to Zinc Binding Sites List in 7oni
Zinc binding site 1 out of 7 in the Structure of Neddylated CUL5 C-Terminal Region-RBX2-ARIH2*


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Neddylated CUL5 C-Terminal Region-RBX2-ARIH2* within 5.0Å range:
probe atom residue distance (Å) B Occ
H:Zn501

b:101.6
occ:1.00
 NE2 H:HIS265 2.0 69.7 1.0
SG H:CYS260 2.3 90.6 1.0
SG H:CYS270 2.3 79.1 1.0
SG H:CYS257 2.3 87.8 1.0
CE1 H:HIS265 2.5 69.7 1.0
CD2 H:HIS265 3.3 69.7 1.0
CB H:CYS257 3.3 87.8 1.0
CB H:CYS270 3.3 79.1 1.0
CB H:CYS260 3.7 90.6 1.0
ND1 H:HIS265 3.8 69.7 1.0
N H:CYS260 3.8 90.6 1.0
CA H:CYS270 3.9 79.1 1.0
O H:CYS260 4.0 90.6 1.0
CG H:HIS265 4.2 69.7 1.0
CA H:CYS260 4.2 90.6 1.0
N H:CYS270 4.5 79.1 1.0
C H:CYS260 4.6 90.6 1.0
CB H:ALA244 4.6 82.7 1.0
CA H:CYS257 4.7 87.8 1.0
CB H:LYS259 4.8 87.9 1.0
C H:LYS259 4.9 87.9 1.0

Zinc binding site 2 out of 7 in 7oni

Go back to Zinc Binding Sites List in 7oni
Zinc binding site 2 out of 7 in the Structure of Neddylated CUL5 C-Terminal Region-RBX2-ARIH2*


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of Neddylated CUL5 C-Terminal Region-RBX2-ARIH2* within 5.0Å range:
probe atom residue distance (Å) B Occ
H:Zn502

b:311.3
occ:1.00
 SG H:CYS161 2.3 269.4 1.0
SG H:CYS139 2.3 299.9 1.0
SG H:CYS164 2.3 253.4 1.0
SG H:CYS142 2.3 303.5 1.0
CB H:CYS139 2.9 299.9 1.0
CB H:CYS164 3.1 253.4 1.0
CB H:CYS142 3.2 303.5 1.0
CB H:CYS161 3.6 269.4 1.0
N H:CYS142 3.9 303.5 1.0
N H:CYS161 3.9 269.4 1.0
CA H:CYS142 4.2 303.5 1.0
CA H:CYS161 4.2 269.4 1.0
CA H:CYS164 4.2 253.4 1.0
N H:CYS164 4.2 253.4 1.0
CA H:CYS139 4.4 299.9 1.0
O H:CYS161 4.4 269.4 1.0
C H:CYS161 4.7 269.4 1.0
C H:VAL141 4.8 298.9 1.0
C H:CYS139 5.0 299.9 1.0

Zinc binding site 3 out of 7 in 7oni

Go back to Zinc Binding Sites List in 7oni
Zinc binding site 3 out of 7 in the Structure of Neddylated CUL5 C-Terminal Region-RBX2-ARIH2*


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Structure of Neddylated CUL5 C-Terminal Region-RBX2-ARIH2* within 5.0Å range:
probe atom residue distance (Å) B Occ
H:Zn503

b:147.1
occ:1.00
 SG H:CYS252 2.3 121.8 1.0
SG H:CYS228 2.3 117.4 1.0
SG H:CYS249 2.3 120.1 1.0
SG H:CYS233 2.3 130.2 1.0
CB H:CYS249 3.0 120.1 1.0
CB H:CYS233 3.4 130.2 1.0
CB H:CYS252 3.6 121.8 1.0
CB H:CYS228 3.7 117.4 1.0
N H:CYS252 4.0 121.8 1.0
CA H:CYS252 4.3 121.8 1.0
CA H:CYS249 4.4 120.1 1.0
CB H:MET235 4.6 126.6 1.0
CG H:MET235 4.7 126.6 1.0
CB H:ARG251 4.7 123.0 1.0
O H:CYS249 4.8 120.1 1.0
OE1 H:GLU254 4.8 113.0 1.0
CA H:CYS233 4.8 130.2 1.0
C H:CYS249 4.8 120.1 1.0
C H:ARG251 5.0 123.0 1.0
C H:CYS252 5.0 121.8 1.0
CA H:CYS228 5.0 117.4 1.0

Zinc binding site 4 out of 7 in 7oni

Go back to Zinc Binding Sites List in 7oni
Zinc binding site 4 out of 7 in the Structure of Neddylated CUL5 C-Terminal Region-RBX2-ARIH2*


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Structure of Neddylated CUL5 C-Terminal Region-RBX2-ARIH2* within 5.0Å range:
probe atom residue distance (Å) B Occ
H:Zn504

b:253.5
occ:1.00
 ND1 H:HIS158 2.0 250.1 1.0
SG H:CYS156 2.3 241.8 1.0
SG H:CYS188 2.3 228.4 1.0
SG H:CYS183 2.3 234.3 1.0
CE1 H:HIS158 2.9 250.1 1.0
CG H:HIS158 3.0 250.1 1.0
CB H:CYS183 3.0 234.3 1.0
CB H:CYS156 3.2 241.8 1.0
CB H:CYS188 3.3 228.4 1.0
CB H:HIS158 3.4 250.1 1.0
NE2 H:HIS158 3.9 250.1 1.0
CD2 H:HIS158 4.0 250.1 1.0
CB H:ALA185 4.2 240.6 1.0
CA H:CYS183 4.5 234.3 1.0
CA H:CYS156 4.6 241.8 1.0
CA H:HIS158 4.7 250.1 1.0
CA H:CYS188 4.7 228.4 1.0
N H:HIS158 4.8 250.1 1.0
CB H:LEU190 4.9 216.1 1.0
N H:ALA185 4.9 240.6 1.0

Zinc binding site 5 out of 7 in 7oni

Go back to Zinc Binding Sites List in 7oni
Zinc binding site 5 out of 7 in the Structure of Neddylated CUL5 C-Terminal Region-RBX2-ARIH2*


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Structure of Neddylated CUL5 C-Terminal Region-RBX2-ARIH2* within 5.0Å range:
probe atom residue distance (Å) B Occ
R:Zn201

b:67.5
occ:1.00
 ND1 R:HIS85 2.0 63.8 1.0
SG R:CYS50 2.3 60.3 1.0
SG R:CYS53 2.3 61.2 1.0
SG R:CYS88 2.3 69.8 1.0
CB R:CYS50 2.9 60.3 1.0
CE1 R:HIS85 2.9 63.8 1.0
CG R:HIS85 3.0 63.8 1.0
CB R:HIS85 3.4 63.8 1.0
CB R:CYS88 3.5 69.8 1.0
CB R:CYS53 3.9 61.2 1.0
NE2 R:HIS85 4.0 63.8 1.0
CD2 R:HIS85 4.0 63.8 1.0
N R:CYS53 4.1 61.2 1.0
N R:HIS85 4.3 63.8 1.0
CA R:CYS50 4.4 60.3 1.0
CA R:HIS85 4.4 63.8 1.0
CA R:CYS53 4.6 61.2 1.0
CB R:ILE52 4.6 56.6 1.0
CB R:CYS61 4.7 73.5 1.0
CA R:CYS88 4.9 69.8 1.0
C R:CYS50 5.0 60.3 1.0

Zinc binding site 6 out of 7 in 7oni

Go back to Zinc Binding Sites List in 7oni
Zinc binding site 6 out of 7 in the Structure of Neddylated CUL5 C-Terminal Region-RBX2-ARIH2*


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of Structure of Neddylated CUL5 C-Terminal Region-RBX2-ARIH2* within 5.0Å range:
probe atom residue distance (Å) B Occ
R:Zn202

b:111.3
occ:1.00
 SG R:CYS61 2.3 73.5 1.0
SG R:CYS64 2.3 74.9 1.0
SG R:CYS73 2.3 78.7 1.0
SG R:CYS87 2.3 73.6 1.0
CB R:CYS64 3.2 74.9 1.0
CB R:CYS73 3.2 78.7 1.0
CB R:CYS61 3.5 73.5 1.0
CB R:CYS87 3.6 73.6 1.0
CA R:CYS73 4.1 78.7 1.0
N R:CYS64 4.3 74.9 1.0
CA R:CYS64 4.3 74.9 1.0
N R:CYS61 4.3 73.5 1.0
CA R:CYS61 4.4 73.5 1.0
CA R:CYS87 4.9 73.6 1.0
O R:CYS61 4.9 73.5 1.0
N R:CYS87 4.9 73.6 1.0
C R:CYS61 4.9 73.5 1.0

Zinc binding site 7 out of 7 in 7oni

Go back to Zinc Binding Sites List in 7oni
Zinc binding site 7 out of 7 in the Structure of Neddylated CUL5 C-Terminal Region-RBX2-ARIH2*


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 7 of Structure of Neddylated CUL5 C-Terminal Region-RBX2-ARIH2* within 5.0Å range:
probe atom residue distance (Å) B Occ
R:Zn203

b:97.3
occ:1.00
 ND1 R:HIS82 2.0 73.2 1.0
SG R:CYS80 2.3 83.5 1.0
SG R:CYS99 2.3 73.8 1.0
SG R:CYS102 2.3 80.2 1.0
CE1 R:HIS82 2.9 73.2 1.0
CB R:CYS80 3.1 83.5 1.0
CB R:CYS99 3.1 73.8 1.0
CG R:HIS82 3.1 73.2 1.0
CB R:HIS82 3.6 73.2 1.0
CB R:CYS102 3.8 80.2 1.0
N R:CYS102 3.8 80.2 1.0
NE2 R:HIS82 4.0 73.2 1.0
O R:CYS102 4.1 80.2 1.0
CD2 R:HIS82 4.2 73.2 1.0
CA R:CYS102 4.3 80.2 1.0
CA R:CYS80 4.4 83.5 1.0
CB R:LEU101 4.4 70.4 1.0
O R:CYS80 4.5 83.5 1.0
C R:CYS80 4.6 83.5 1.0
CA R:CYS99 4.6 73.8 1.0
C R:CYS102 4.7 80.2 1.0
C R:LEU101 4.9 70.4 1.0
CA R:HIS82 4.9 73.2 1.0
N R:HIS82 5.0 73.2 1.0
N R:LEU101 5.0 70.4 1.0

Reference:

S.P.Kostrhon, J.R.Prabu. CUL5-ARIH2 E3-E3 Ubiquitin Ligase Structure Reveals Cullin-Specific NEDD8 Activation To Be Published.
DOI: 10.1038/S41589-021-00858-8
Page generated: Fri Aug 22 03:05:13 2025

Last articles

Zn in 7ZOK
Zn in 7ZO7
Zn in 7ZO6
Zn in 7ZOC
Zn in 7ZO5
Zn in 7ZO4
Zn in 7ZO3
Zn in 7ZO2
Zn in 7ZMX
Zn in 7ZNQ
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy