Zinc in PDB 7nz9: Crystal Structure of Mouse ADAT2/ADAT3 Trna Deamination Complex V128L Mutant

All present enzymatic activity of Crystal Structure of Mouse ADAT2/ADAT3 Trna Deamination Complex V128L Mutant:
3.5.4.33;

The structure of Crystal Structure of Mouse ADAT2/ADAT3 Trna Deamination Complex V128L Mutant, PDB code: 7nz9 was solved by E.Ramos Morales, C.Romier, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.38 / 1.99
Space group	P 2 21 21
Cell size a, b, c (Å), α, β, γ (°)	51.976, 106.814, 129.668, 90, 90, 90
R / Rfree (%)	18.9 / 21.8

The binding sites of Zinc atom in the Crystal Structure of Mouse ADAT2/ADAT3 Trna Deamination Complex V128L Mutant (pdb code 7nz9). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Mouse ADAT2/ADAT3 Trna Deamination Complex V128L Mutant, PDB code: 7nz9:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Mouse ADAT2/ADAT3 Trna Deamination Complex V128L Mutant


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Mouse ADAT2/ADAT3 Trna Deamination Complex V128L Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn200 b:32.3 occ:1.00 O A:HOH319 2.0 32.6 1.0 ND1 A:HIS71 2.2 35.3 1.0 SG A:CYS110 2.2 31.9 1.0 SG A:CYS107 2.3 30.4 1.0 CE1 A:HIS71 3.1 38.1 1.0 CG A:HIS71 3.2 36.8 1.0 CB A:CYS110 3.2 32.3 1.0 CB A:CYS107 3.4 32.4 1.0 CB A:HIS71 3.5 32.0 1.0 N A:CYS107 3.8 30.2 1.0 N A:CYS110 3.9 24.9 1.0 OE2 A:GLU73 3.9 34.9 1.0 CA A:CYS107 4.1 33.8 1.0 CE A:MET109 4.1 30.8 1.0 O A:HOH305 4.2 40.2 1.0 OE1 A:GLU73 4.2 34.1 1.0 CA A:CYS110 4.2 28.0 1.0 O A:HOH383 4.2 43.3 1.0 NE2 A:HIS71 4.2 35.1 1.0 CD A:GLU73 4.3 35.4 1.0 CD2 A:HIS71 4.3 33.9 1.0 C A:CYS107 4.7 28.6 1.0 O A:HOH379 4.7 35.9 1.0 O A:CYS107 4.8 31.7 1.0 O A:HOH327 4.8 41.8 1.0 CB A:MET109 4.9 28.1 1.0 NE2 B:HIS298 4.9 34.4 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Mouse ADAT2/ADAT3 Trna Deamination Complex V128L Mutant


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Mouse ADAT2/ADAT3 Trna Deamination Complex V128L Mutant within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn400 b:31.7 occ:1.00 OD2 B:ASP348 2.0 34.4 1.0 ND1 B:HIS223 2.2 31.2 1.0 SG B:CYS289 2.3 28.6 1.0 SG B:CYS292 2.3 30.9 1.0 CG B:ASP348 2.9 35.5 1.0 OD1 B:ASP348 3.1 39.6 1.0 CE1 B:HIS223 3.1 29.3 1.0 CG B:HIS223 3.2 31.7 1.0 CB B:CYS292 3.3 28.2 1.0 CB B:CYS289 3.4 28.4 1.0 CB B:HIS223 3.5 28.3 1.0 N B:CYS289 3.8 31.3 1.0 O B:HOH619 4.0 31.5 1.0 N B:CYS292 4.0 26.0 1.0 CA B:CYS289 4.1 29.1 1.0 NE2 B:HIS223 4.3 31.2 1.0 CA B:CYS292 4.3 29.6 1.0 CB B:ASP348 4.3 32.3 1.0 CD2 B:HIS223 4.3 30.9 1.0 CE B:MET291 4.4 26.6 1.0 C B:CYS289 4.7 27.0 1.0 O B:CYS289 4.8 29.5 1.0 C B:PRO288 4.9 30.7 1.0 CA B:PRO349 4.9 38.9 1.0 N B:PRO349 5.0 37.3 1.0 CB B:MET291 5.0 25.2 1.0

E.Ramos Morales, C.Romier. The Structure of the Mouse ADAT2/ADAT3 Complex Reveals the Molecular Basis For Mammalian Trna Wobble Adenosine to Inosine Deamination To Be Published.