Zinc in PDB 7krp: Structure of Sars-Cov-2 Backtracked Complex Complex Bound to NSP13 Helicase - Btc (Local Refinement)

All present enzymatic activity of Structure of Sars-Cov-2 Backtracked Complex Complex Bound to NSP13 Helicase - Btc (Local Refinement):
2.7.7.48;

The structure of Structure of Sars-Cov-2 Backtracked Complex Complex Bound to NSP13 Helicase - Btc (Local Refinement) also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Zinc atom in the Structure of Sars-Cov-2 Backtracked Complex Complex Bound to NSP13 Helicase - Btc (Local Refinement) (pdb code 7krp). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of Sars-Cov-2 Backtracked Complex Complex Bound to NSP13 Helicase - Btc (Local Refinement), PDB code: 7krp:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of Sars-Cov-2 Backtracked Complex Complex Bound to NSP13 Helicase - Btc (Local Refinement)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Sars-Cov-2 Backtracked Complex Complex Bound to NSP13 Helicase - Btc (Local Refinement) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1001 b:36.9 occ:1.00 ND1 A:HIS295 2.1 19.4 1.0 SG A:CYS310 2.3 17.1 1.0 SG A:CYS301 2.3 23.2 1.0 SG A:CYS306 2.3 20.1 1.0 CE1 A:HIS295 2.7 19.4 1.0 O A:CYS306 3.0 20.1 1.0 CG A:HIS295 3.3 19.4 1.0 CB A:CYS301 3.5 23.2 1.0 CB A:CYS310 3.5 17.1 1.0 CB A:CYS306 3.7 20.1 1.0 CA A:CYS301 3.8 23.2 1.0 C A:CYS306 3.8 20.1 1.0 NE2 A:HIS295 3.9 19.4 1.0 CB A:HIS295 4.0 19.4 1.0 N A:HIS295 4.2 19.4 1.0 CD2 A:HIS295 4.3 19.4 1.0 CA A:CYS306 4.3 20.1 1.0 N A:CYS301 4.6 23.2 1.0 CA A:HIS295 4.6 19.4 1.0 O A:HIS295 4.7 19.4 1.0 CA A:CYS310 4.8 17.1 1.0 N A:CYS310 4.8 17.1 1.0 N A:ILE307 4.8 19.3 1.0 N A:LEU302 4.8 22.4 1.0 C A:CYS301 4.9 23.2 1.0

Zinc binding site 2 out of 2 in the Structure of Sars-Cov-2 Backtracked Complex Complex Bound to NSP13 Helicase - Btc (Local Refinement)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of Sars-Cov-2 Backtracked Complex Complex Bound to NSP13 Helicase - Btc (Local Refinement) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1002 b:49.2 occ:1.00 ND1 A:HIS642 2.1 25.4 1.0 SG A:CYS645 2.3 32.1 1.0 SG A:CYS487 2.3 28.4 1.0 SG A:CYS646 2.3 29.9 1.0 CG A:HIS642 2.9 25.4 1.0 CE1 A:HIS642 3.1 25.4 1.0 CB A:HIS642 3.2 25.4 1.0 CB A:CYS646 3.5 29.9 1.0 CB A:CYS487 3.6 28.4 1.0 N A:CYS487 3.6 28.4 1.0 CB A:CYS645 3.7 32.1 1.0 N A:CYS646 3.8 29.9 1.0 CE1 A:PHE571 3.9 24.2 1.0 CD2 A:HIS642 4.1 25.4 1.0 NE2 A:HIS642 4.1 25.4 1.0 CA A:CYS487 4.1 28.4 1.0 CA A:HIS642 4.2 25.4 1.0 CA A:CYS646 4.2 29.9 1.0 C A:CYS645 4.3 32.1 1.0 CD1 A:PHE571 4.4 24.2 1.0 CA A:CYS645 4.5 32.1 1.0 C A:GLY486 4.5 27.0 1.0 CA A:GLY486 4.7 27.0 1.0 CZ A:PHE571 4.7 24.2 1.0 NZ A:LYS532 4.8 24.5 1.0 O A:HIS642 5.0 25.4 1.0 CE A:LYS532 5.0 24.5 1.0 N A:CYS645 5.0 32.1 1.0

B.Malone, J.Chen, Q.Wang, E.C.Llewellyn, Y.J.Choi, P.D.B.Olinares, X.Cao, C.Hernandez, E.Eng, B.T.Chait, D.E.Shaw, R.Landick, S.A.Darst, E.A.Campbell. Structural Basis For Backtracking By the Sars-Cov-2 Replication-Transcription Complex Proc.Natl.Acad.Sci.Usa 2021.
ISSN: ESSN 1091-6490