Zinc in PDB 7fa1: Crystal Structure of N-Terminus of the Non-Structural Protein 2 From Sars Coronavirus

The structure of Crystal Structure of N-Terminus of the Non-Structural Protein 2 From Sars Coronavirus, PDB code: 7fa1 was solved by Y.Y.Li, Z.L.Ren, Z.H.Bao, Z.H.Ming, L.M.Yan, Z.Y.Lou, Z.H.Rao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	33.33 / 1.60
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	67.092, 76.821, 64.98, 90, 90, 90
R / Rfree (%)	18.8 / 22.2

The binding sites of Zinc atom in the Crystal Structure of N-Terminus of the Non-Structural Protein 2 From Sars Coronavirus (pdb code 7fa1). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Crystal Structure of N-Terminus of the Non-Structural Protein 2 From Sars Coronavirus, PDB code: 7fa1:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the Crystal Structure of N-Terminus of the Non-Structural Protein 2 From Sars Coronavirus


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of N-Terminus of the Non-Structural Protein 2 From Sars Coronavirus within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1001 b:24.5 occ:1.00 SG A:CYS147 2.3 17.6 1.0 SG A:CYS162 2.3 15.7 1.0 SG A:CYS165 2.3 17.3 1.0 SG A:CYS144 2.4 16.1 1.0 CB A:CYS144 3.0 20.6 1.0 CB A:CYS162 3.1 14.9 1.0 CB A:CYS147 3.3 16.2 1.0 CB A:CYS165 3.4 15.7 1.0 N A:CYS147 3.8 14.8 1.0 N A:CYS165 3.9 17.1 1.0 CA A:CYS147 4.1 16.5 1.0 CA A:CYS165 4.2 16.4 1.0 CB A:HIS164 4.3 17.0 1.0 O A:HOH1126 4.4 23.0 1.0 CA A:CYS144 4.5 17.5 1.0 CA A:CYS162 4.6 14.3 1.0 C A:HIS164 4.6 18.3 1.0 CB A:THR167 4.7 20.3 1.0 CB A:HIS146 4.8 15.8 1.0 N A:HIS164 4.8 17.4 1.0 CA A:HIS164 4.8 15.2 1.0 OG1 A:THR167 4.8 18.5 1.0 C A:HIS146 4.9 22.4 1.0 C A:CYS147 4.9 15.5 1.0 C A:CYS165 4.9 18.0 1.0 C A:CYS144 5.0 18.2 1.0

Zinc binding site 2 out of 3 in the Crystal Structure of N-Terminus of the Non-Structural Protein 2 From Sars Coronavirus


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of N-Terminus of the Non-Structural Protein 2 From Sars Coronavirus within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1002 b:31.1 occ:1.00 NE2 A:HIS203 2.2 20.6 1.0 SG A:CYS191 2.3 22.7 1.0 SG A:CYS237 2.3 20.8 1.0 SG A:CYS194 2.3 23.5 1.0 CB A:CYS191 3.1 24.2 1.0 CE1 A:HIS203 3.2 25.6 1.0 CD2 A:HIS203 3.2 29.1 1.0 CB A:CYS237 3.2 19.5 1.0 CB A:CYS194 3.3 26.0 1.0 N A:CYS194 3.8 25.5 1.0 CA A:CYS194 4.0 25.6 1.0 ND1 A:HIS203 4.3 20.9 1.0 CG A:HIS203 4.3 23.1 1.0 OH A:TYR234 4.4 22.1 1.0 CD1 A:TYR208 4.5 20.1 1.0 CA A:CYS191 4.5 19.9 1.0 CB A:ALA193 4.6 20.9 1.0 CA A:CYS237 4.7 22.5 1.0 C A:ALA193 4.7 28.1 1.0 O A:CYS191 4.9 24.2 1.0 C A:CYS191 4.9 24.0 1.0 O A:HOH1277 4.9 27.4 1.0 CE1 A:TYR208 5.0 19.6 1.0

Zinc binding site 3 out of 3 in the Crystal Structure of N-Terminus of the Non-Structural Protein 2 From Sars Coronavirus


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of N-Terminus of the Non-Structural Protein 2 From Sars Coronavirus within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1003 b:33.9 occ:1.00 NE2 A:HIS55 2.1 23.0 1.0 NE2 A:HIS57 2.1 23.1 1.0 SG A:CYS52 2.3 25.2 1.0 SG A:CYS21 2.4 26.6 1.0 CE1 A:HIS55 3.0 32.4 1.0 CE1 A:HIS57 3.1 26.3 1.0 CD2 A:HIS55 3.1 26.3 1.0 CD2 A:HIS57 3.1 24.4 1.0 CB A:CYS52 3.2 25.6 1.0 CB A:CYS21 3.2 25.3 1.0 CD1 A:ILE22 4.1 26.1 1.0 ND1 A:HIS55 4.2 29.4 1.0 ND1 A:HIS57 4.2 23.1 1.0 CG A:HIS55 4.2 25.9 1.0 CG A:HIS57 4.3 22.5 1.0 O A:HOH1368 4.4 37.1 1.0 CG1 A:ILE22 4.5 24.0 1.0 CA A:CYS21 4.5 23.7 1.0 O A:HOH1162 4.5 25.4 1.0 N A:ILE22 4.5 26.0 1.0 CA A:CYS52 4.6 28.1 1.0 C A:CYS21 4.6 29.5 1.0 O A:HOH1406 4.7 42.2 1.0 CD2 A:LEU19 4.9 21.2 1.0 N A:CYS52 5.0 25.1 1.0

Y.Y.Li, Z.H.Ming, L.M.Yan, Z.Y.Lou, Z.H.Rao. Crystal Structure of N-Terminus of the Non-Structural Protein 2 From Sars Coronavirus To Be Published.