Zinc in PDB 7f75: Cryo-Em Structure of Spx-Dependent Transcription Activation Complex

Enzymatic activity of Cryo-Em Structure of Spx-Dependent Transcription Activation Complex

All present enzymatic activity of Cryo-Em Structure of Spx-Dependent Transcription Activation Complex:
2.7.7.6;

Other elements in 7f75:

The structure of Cryo-Em Structure of Spx-Dependent Transcription Activation Complex also contains other interesting chemical elements:

Magnesium (Mg) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the Cryo-Em Structure of Spx-Dependent Transcription Activation Complex (pdb code 7f75). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Cryo-Em Structure of Spx-Dependent Transcription Activation Complex, PDB code: 7f75:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 7f75

Go back to Zinc Binding Sites List in 7f75
Zinc binding site 1 out of 2 in the Cryo-Em Structure of Spx-Dependent Transcription Activation Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of Spx-Dependent Transcription Activation Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn1502

b:89.9
occ:1.00
CG2 D:VAL80 2.5 66.3 1.0
SG D:CYS75 2.5 85.0 1.0
CB D:CYS75 2.7 85.0 1.0
SG D:CYS60 2.8 86.1 1.0
CB D:VAL80 2.8 66.3 1.0
N D:VAL80 3.8 66.3 1.0
CG1 D:VAL80 3.9 66.3 1.0
CA D:VAL80 3.9 66.3 1.0
N D:CYS78 3.9 59.3 1.0
CA D:CYS75 4.2 85.0 1.0
CB D:ARG77 4.3 70.2 1.0
N D:ARG77 4.4 70.2 1.0
N D:GLY79 4.4 57.3 1.0
CB D:CYS78 4.5 59.3 1.0
C D:CYS75 4.6 85.0 1.0
CB D:CYS60 4.6 86.1 1.0
SG D:CYS78 4.6 59.3 1.0
CA D:CYS78 4.7 59.3 1.0
CA D:ARG77 4.7 70.2 1.0
O D:VAL80 4.8 66.3 1.0
N D:ASP76 4.8 75.6 1.0
C D:ARG77 4.8 70.2 1.0
C D:VAL80 4.8 66.3 1.0
N D:CYS75 4.9 85.0 1.0
C D:GLY79 4.9 57.3 1.0
N D:HIS61 5.0 81.8 1.0
C D:CYS78 5.0 59.3 1.0

Zinc binding site 2 out of 2 in 7f75

Go back to Zinc Binding Sites List in 7f75
Zinc binding site 2 out of 2 in the Cryo-Em Structure of Spx-Dependent Transcription Activation Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryo-Em Structure of Spx-Dependent Transcription Activation Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn1503

b:29.2
occ:1.00
SG D:CYS902 2.5 8.6 1.0
SG D:CYS892 2.5 9.8 1.0
SG D:CYS899 2.5 7.7 1.0
CB D:CYS892 2.7 9.8 1.0
SG D:CYS818 2.8 16.1 1.0
CB D:CYS899 3.0 7.7 1.0
CB D:CYS902 3.2 8.6 1.0
CA D:CYS892 3.3 9.8 1.0
N D:CYS899 3.8 7.7 1.0
CA D:CYS899 4.0 7.7 1.0
N D:ASN893 4.0 7.8 1.0
CB D:CYS818 4.1 16.1 1.0
C D:CYS892 4.2 9.8 1.0
N D:CYS818 4.3 16.1 1.0
N D:CYS892 4.3 9.8 1.0
O D:CYS818 4.5 16.1 1.0
CA D:CYS902 4.6 8.6 1.0
CA D:CYS818 4.7 16.1 1.0
C D:VAL898 4.7 4.4 1.0
N D:CYS902 4.9 8.6 1.0
OD1 D:ASP817 4.9 11.1 1.0
C D:CYS818 5.0 16.1 1.0
OG1 D:THR894 5.0 5.6 1.0

Reference:

J.Shi, F.Li, A.Wen, L.Yu, L.Wang, F.Wang, Y.Jin, S.Jin, Y.Feng, W.Lin. Structural Basis of Transcription Activation By the Global Regulator Spx. Nucleic Acids Res. 2021.
ISSN: ESSN 1362-4962
PubMed: 34530448
DOI: 10.1093/NAR/GKAB790
Page generated: Fri Nov 5 16:51:41 2021

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