Zinc in PDB 7f51: Crystal Structure of HST2 in Complex with 2'-O-Benzoyl Adp Ribose

All present enzymatic activity of Crystal Structure of HST2 in Complex with 2'-O-Benzoyl Adp Ribose:
2.3.1.286;

The structure of Crystal Structure of HST2 in Complex with 2'-O-Benzoyl Adp Ribose, PDB code: 7f51 was solved by D.Wang, F.Yan, Y.Chen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.04 / 1.98
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	42.166, 67.363, 92.51, 90, 90, 90
R / Rfree (%)	18.1 / 22

The binding sites of Zinc atom in the Crystal Structure of HST2 in Complex with 2'-O-Benzoyl Adp Ribose (pdb code 7f51). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of HST2 in Complex with 2'-O-Benzoyl Adp Ribose, PDB code: 7f51:

Zinc binding site 1 out of 1 in the Crystal Structure of HST2 in Complex with 2'-O-Benzoyl Adp Ribose


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of HST2 in Complex with 2'-O-Benzoyl Adp Ribose within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:34.7 occ:1.00 SG A:CYS143 2.3 41.4 1.0 SG A:CYS146 2.3 40.0 1.0 SG A:CYS170 2.3 37.4 1.0 SG A:CYS173 2.3 31.9 1.0 CB A:CYS143 3.1 40.8 1.0 CB A:CYS170 3.1 36.5 1.0 CB A:CYS173 3.4 37.0 1.0 CB A:CYS146 3.4 41.5 1.0 N A:CYS146 3.7 44.3 1.0 N A:CYS173 3.8 40.1 1.0 CA A:CYS146 4.1 43.8 1.0 CA A:CYS173 4.1 39.4 1.0 CA A:CYS143 4.6 40.7 1.0 O A:HOH634 4.6 47.2 1.0 CA A:CYS170 4.6 37.3 1.0 C A:CYS173 4.6 39.1 1.0 C A:GLY145 4.7 45.8 1.0 N A:GLY174 4.7 37.9 1.0 N A:GLY147 4.7 42.1 1.0 C A:CYS146 4.7 44.6 1.0 CB A:VAL172 4.7 41.4 1.0 CB A:LYS148 4.8 48.4 1.0 C A:VAL172 4.8 40.5 1.0 CB A:GLU175 4.9 33.8 1.0 N A:GLU175 4.9 33.5 1.0 N A:GLY145 4.9 41.6 1.0 CA A:GLY145 4.9 42.4 1.0 N A:LYS148 4.9 44.6 1.0

D.Wang, F.Yan, P.Wu, K.Ge, M.Li, T.Li, Y.Gao, C.Peng, Y.Chen. Global Profiling of Regulatory Elements in the Histone Benzoylation Pathway. Nat Commun V. 13 1369 2022.
ISSN: ESSN 2041-1723
PubMed: 35296687
DOI: 10.1038/S41467-022-29057-2