Zinc in PDB 7elc: Structure of Monomeric Complex of Macv L Bound to Z and 3'-Vrna

Enzymatic activity of Structure of Monomeric Complex of Macv L Bound to Z and 3'-Vrna

All present enzymatic activity of Structure of Monomeric Complex of Macv L Bound to Z and 3'-Vrna:
2.7.7.48;

Other elements in 7elc:

The structure of Structure of Monomeric Complex of Macv L Bound to Z and 3'-Vrna also contains other interesting chemical elements:

Manganese (Mn) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the Structure of Monomeric Complex of Macv L Bound to Z and 3'-Vrna (pdb code 7elc). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Structure of Monomeric Complex of Macv L Bound to Z and 3'-Vrna, PDB code: 7elc:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in 7elc

Go back to Zinc Binding Sites List in 7elc
Zinc binding site 1 out of 4 in the Structure of Monomeric Complex of Macv L Bound to Z and 3'-Vrna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Monomeric Complex of Macv L Bound to Z and 3'-Vrna within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn2302

b:68.6
occ:1.00
ND1 A:HIS472 2.0 47.0 1.0
SG A:CYS284 2.4 39.0 1.0
SG A:CYS287 2.4 38.9 1.0
SG A:CYS470 2.4 67.4 1.0
CE1 A:HIS472 2.5 47.0 1.0
CB A:CYS284 3.1 39.0 1.0
CG A:HIS472 3.1 47.0 1.0
CB A:CYS287 3.4 38.9 1.0
CB A:CYS470 3.6 67.4 1.0
NE2 A:HIS472 3.6 47.0 1.0
CA A:CYS470 3.7 67.4 1.0
CB A:HIS472 3.9 47.0 1.0
N A:CYS287 3.9 38.9 1.0
CD2 A:HIS472 3.9 47.0 1.0
C A:CYS470 4.1 67.4 1.0
O A:CYS470 4.2 67.4 1.0
CA A:CYS287 4.2 38.9 1.0
CA A:CYS284 4.5 39.0 1.0
C A:PHE286 4.9 33.7 1.0
CB A:PHE286 4.9 33.7 1.0
O A:ILE469 4.9 69.3 1.0
N A:ARG471 4.9 58.8 1.0
C A:CYS284 5.0 39.0 1.0
O A:CYS284 5.0 39.0 1.0
N A:HIS472 5.0 47.0 1.0

Zinc binding site 2 out of 4 in 7elc

Go back to Zinc Binding Sites List in 7elc
Zinc binding site 2 out of 4 in the Structure of Monomeric Complex of Macv L Bound to Z and 3'-Vrna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of Monomeric Complex of Macv L Bound to Z and 3'-Vrna within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn2303

b:94.6
occ:1.00
SG A:CYS1650 2.4 76.8 1.0
SG A:CYS1655 2.4 66.7 1.0
SG A:CYS1652 2.4 78.4 1.0
SG A:CYS1664 2.4 59.4 1.0
CB A:CYS1650 2.7 76.8 1.0
CB A:CYS1655 3.0 66.7 1.0
CB A:CYS1664 3.3 59.4 1.0
N A:CYS1655 3.3 66.7 1.0
N A:CYS1652 3.5 78.4 1.0
CB A:CYS1652 3.6 78.4 1.0
CA A:CYS1655 3.7 66.7 1.0
C A:CYS1650 3.8 76.8 1.0
CA A:CYS1650 3.8 76.8 1.0
N A:THR1651 3.9 81.4 1.0
CA A:CYS1652 4.0 78.4 1.0
C A:ILE1654 4.2 65.7 1.0
O A:CYS1650 4.3 76.8 1.0
CA A:CYS1664 4.4 59.4 1.0
N A:ILE1654 4.4 65.7 1.0
N A:CYS1664 4.4 59.4 1.0
CB A:ILE1654 4.5 65.7 1.0
C A:CYS1652 4.5 78.4 1.0
C A:THR1651 4.5 81.4 1.0
CA A:ILE1654 4.6 65.7 1.0
CA A:THR1651 4.6 81.4 1.0
O A:CYS1652 4.8 78.4 1.0
N A:CYS1650 4.9 76.8 1.0
C A:CYS1655 4.9 66.7 1.0
N A:GLU1653 5.0 73.6 1.0
CG2 A:ILE1654 5.0 65.7 1.0

Zinc binding site 3 out of 4 in 7elc

Go back to Zinc Binding Sites List in 7elc
Zinc binding site 3 out of 4 in the Structure of Monomeric Complex of Macv L Bound to Z and 3'-Vrna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Structure of Monomeric Complex of Macv L Bound to Z and 3'-Vrna within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn101

b:80.5
occ:1.00
SG B:CYS61 2.4 58.7 1.0
SG B:CYS58 2.4 59.0 1.0
SG B:CYS39 2.4 45.4 1.0
SG B:CYS42 2.4 44.4 1.0
CB B:CYS61 3.2 58.7 1.0
CB B:CYS58 3.2 59.0 1.0
CB B:CYS39 3.5 45.4 1.0
CB B:CYS42 3.5 44.4 1.0
NE B:ARG60 4.0 60.7 1.0
N B:CYS61 4.2 58.7 1.0
CA B:CYS61 4.2 58.7 1.0
N B:CYS42 4.3 44.4 1.0
CG B:ARG60 4.4 60.7 1.0
CA B:CYS58 4.5 59.0 1.0
CB B:ALA45 4.5 47.3 1.0
CA B:CYS42 4.5 44.4 1.0
N B:CYS58 4.6 59.0 1.0
CD B:ARG60 4.6 60.7 1.0
CZ B:ARG60 4.7 60.7 1.0
NH2 B:ARG60 4.8 60.7 1.0
CA B:CYS39 4.8 45.4 1.0

Zinc binding site 4 out of 4 in 7elc

Go back to Zinc Binding Sites List in 7elc
Zinc binding site 4 out of 4 in the Structure of Monomeric Complex of Macv L Bound to Z and 3'-Vrna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Structure of Monomeric Complex of Macv L Bound to Z and 3'-Vrna within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn102

b:84.7
occ:1.00
NE2 B:HIS55 2.0 60.9 1.0
CE1 B:HIS55 2.3 60.9 1.0
SG B:CYS75 2.4 52.9 1.0
SG B:CYS72 2.4 53.8 1.0
SG B:CYS52 2.4 68.6 1.0
CB B:CYS52 2.5 68.6 1.0
CD2 B:HIS55 3.3 60.9 1.0
ND1 B:HIS55 3.5 60.9 1.0
CB B:CYS75 3.5 52.9 1.0
CB B:CYS72 3.5 53.8 1.0
N B:CYS75 4.0 52.9 1.0
CG B:HIS55 4.0 60.9 1.0
CA B:CYS52 4.0 68.6 1.0
CA B:CYS75 4.4 52.9 1.0
N B:ASN53 4.4 72.1 1.0
CB B:ILE74 4.5 49.8 1.0
C B:CYS52 4.6 68.6 1.0
N B:CYS52 4.8 68.6 1.0
OD1 B:ASP54 4.8 69.9 1.0
CD2 B:LEU79 4.9 67.2 1.0
CA B:CYS72 4.9 53.8 1.0
CG2 B:ILE74 4.9 49.8 1.0
C B:ILE74 5.0 49.8 1.0

Reference:

R.Peng, X.Xu, Q.Peng, Y.Shi. Cryo-Em Structures of Lassa and Machupo Virus Polymerases Complexed with Cognate Regulatory Z Proteins Identify Targets For Antivirals. Nat Microbiol 2021.
ISSN: ESSN 2058-5276
Page generated: Mon Jul 12 17:03:37 2021

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy