Zinc in PDB 7dia: Falcilysin in Complex with Mefloquine

The structure of Falcilysin in Complex with Mefloquine, PDB code: 7dia was solved by J.Q.Lin, A.El Sahili, J.Lescar, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.77 / 1.55
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	93.46, 105.74, 126.35, 90, 90, 90
R / Rfree (%)	17.4 / 19.7

The structure of Falcilysin in Complex with Mefloquine also contains other interesting chemical elements:

Fluorine

(F)

12 atoms

The binding sites of Zinc atom in the Falcilysin in Complex with Mefloquine (pdb code 7dia). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Falcilysin in Complex with Mefloquine, PDB code: 7dia:

Zinc binding site 1 out of 1 in the Falcilysin in Complex with Mefloquine


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Falcilysin in Complex with Mefloquine within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1211 b:42.9 occ:1.00 NE2 A:HIS133 2.0 34.1 1.0 NE2 A:HIS129 2.1 24.9 1.0 OE1 A:GLU243 2.3 34.1 1.0 O A:HOH1703 2.3 40.5 1.0 CE1 A:HIS133 2.8 33.3 1.0 CE1 A:HIS129 3.0 24.9 1.0 CD2 A:HIS133 3.1 27.9 1.0 CD2 A:HIS129 3.2 24.4 1.0 CD A:GLU243 3.2 43.6 1.0 OE2 A:GLU243 3.4 41.9 1.0 O A:HOH2317 3.9 48.6 1.0 ND1 A:HIS133 4.0 38.4 1.0 ND1 A:HIS129 4.1 22.7 1.0 CG A:HIS133 4.2 25.8 1.0 CG A:HIS129 4.2 22.0 1.0 CG A:GLU243 4.6 34.6 1.0 OE1 A:GLU132 4.6 35.0 1.0 CG2 A:VAL240 4.8 19.0 1.0 CB A:GLU243 4.9 26.6 1.0

J.Q.Lin, J.Q.Lin, A.El Sahili, J.Lescar. N/A N/A.