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Zinc in PDB 7cwf: Crystal Structure of PDE8A Catalytic Domain in Complex with 2CEnzymatic activity of Crystal Structure of PDE8A Catalytic Domain in Complex with 2C
All present enzymatic activity of Crystal Structure of PDE8A Catalytic Domain in Complex with 2C:
3.1.4.53; Protein crystallography data
The structure of Crystal Structure of PDE8A Catalytic Domain in Complex with 2C, PDB code: 7cwf
was solved by
Y.Huang,
X.-N.Wu,
Q.Zhou,
Y.Wu,
H.-B.Luo,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7cwf:
The structure of Crystal Structure of PDE8A Catalytic Domain in Complex with 2C also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of PDE8A Catalytic Domain in Complex with 2C
(pdb code 7cwf). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of PDE8A Catalytic Domain in Complex with 2C, PDB code: 7cwf: Zinc binding site 1 out of 1 in 7cwfGo back to Zinc Binding Sites List in 7cwf
Zinc binding site 1 out
of 1 in the Crystal Structure of PDE8A Catalytic Domain in Complex with 2C
Mono view Stereo pair view
Reference:
Y.Huang,
X.-N.Wu,
Q.Zhou,
Y.Wu,
H.-B.Luo.
Discovery of Highly Selective and Orally Bioavailable Phosphodiesterase-8A Inhibitors. Structure-Activity Relationship, Crystal Structures, and in Vivo Studies To Be Published.
Page generated: Fri Sep 24 17:04:27 2021
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