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Zinc in PDB 7cid: Crystal Structure of P.Aeruginosa Lpxc in Complex with InhibitorEnzymatic activity of Crystal Structure of P.Aeruginosa Lpxc in Complex with Inhibitor
All present enzymatic activity of Crystal Structure of P.Aeruginosa Lpxc in Complex with Inhibitor:
3.5.1.108; Protein crystallography data
The structure of Crystal Structure of P.Aeruginosa Lpxc in Complex with Inhibitor, PDB code: 7cid
was solved by
L.M.Baker,
M.Mima,
A.Surgenor,
A.Robertson,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7cid:
The structure of Crystal Structure of P.Aeruginosa Lpxc in Complex with Inhibitor also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of P.Aeruginosa Lpxc in Complex with Inhibitor
(pdb code 7cid). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of P.Aeruginosa Lpxc in Complex with Inhibitor, PDB code: 7cid: Zinc binding site 1 out of 1 in 7cidGo back to Zinc Binding Sites List in 7cid
Zinc binding site 1 out
of 1 in the Crystal Structure of P.Aeruginosa Lpxc in Complex with Inhibitor
Mono view Stereo pair view
Reference:
Y.Yamada,
H.Takashima,
D.L.Walmsley,
F.Ushiyama,
Y.Matsuda,
H.Kanazawa,
T.Yamaguchi-Sasaki,
N.Tanaka-Yamamoto,
J.Yamagishi,
R.Kurimoto-Tsuruta,
Y.Ogata,
N.Ohtake,
H.Angove,
L.Baker,
R.Harris,
A.Macias,
A.Robertson,
A.Surgenor,
H.Watanabe,
K.Nakano,
M.Mima,
K.Iwamoto,
A.Okada,
I.Takata,
K.Hitaka,
A.Tanaka,
K.Fujita,
H.Sugiyama,
R.E.Hubbard.
Fragment-Based Discovery of Novel Non-Hydroxamate Lpxc Inhibitors with Antibacterial Activity. J.Med.Chem. 2020.
Page generated: Wed Dec 16 13:40:59 2020
ISSN: ISSN 0022-2623 PubMed: 33210531 DOI: 10.1021/ACS.JMEDCHEM.0C01215 |
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