|
Zinc in PDB 7ci8: Crystal Structure of P.Aeruginosa Lpxc in Complex with InhibitorEnzymatic activity of Crystal Structure of P.Aeruginosa Lpxc in Complex with Inhibitor
All present enzymatic activity of Crystal Structure of P.Aeruginosa Lpxc in Complex with Inhibitor:
3.5.1.108; Protein crystallography data
The structure of Crystal Structure of P.Aeruginosa Lpxc in Complex with Inhibitor, PDB code: 7ci8
was solved by
M.Mima,
L.M.Baker,
A.Surgenor,
A.Robertson,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7ci8:
The structure of Crystal Structure of P.Aeruginosa Lpxc in Complex with Inhibitor also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of P.Aeruginosa Lpxc in Complex with Inhibitor
(pdb code 7ci8). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of P.Aeruginosa Lpxc in Complex with Inhibitor, PDB code: 7ci8: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 7ci8Go back to Zinc Binding Sites List in 7ci8
Zinc binding site 1 out
of 2 in the Crystal Structure of P.Aeruginosa Lpxc in Complex with Inhibitor
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 7ci8Go back to Zinc Binding Sites List in 7ci8
Zinc binding site 2 out
of 2 in the Crystal Structure of P.Aeruginosa Lpxc in Complex with Inhibitor
Mono view Stereo pair view
Reference:
Y.Yamada,
H.Takashima,
D.L.Walmsley,
F.Ushiyama,
Y.Matsuda,
H.Kanazawa,
T.Yamaguchi-Sasaki,
N.Tanaka-Yamamoto,
J.Yamagishi,
R.Kurimoto-Tsuruta,
Y.Ogata,
N.Ohtake,
H.Angove,
L.Baker,
R.Harris,
A.Macias,
A.Robertson,
A.Surgenor,
H.Watanabe,
K.Nakano,
M.Mima,
K.Iwamoto,
A.Okada,
I.Takata,
K.Hitaka,
A.Tanaka,
K.Fujita,
H.Sugiyama,
R.E.Hubbard.
Fragment-Based Discovery of Novel Non-Hydroxamate Lpxc Inhibitors with Antibacterial Activity. J.Med.Chem. 2020.
Page generated: Wed Dec 16 13:40:46 2020
ISSN: ISSN 0022-2623 PubMed: 33210531 DOI: 10.1021/ACS.JMEDCHEM.0C01215 |
Last articlesZn in 8WB0Zn in 8WAX Zn in 8WAU Zn in 8WAZ Zn in 8WAY Zn in 8WAV Zn in 8WAW Zn in 8WAT Zn in 8W7M Zn in 8WD3 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |