Zinc in PDB 7cdh: Crystal Structure of Betaaspartyl Dipeptidase From Thermophilic Keratin Degrading Fervidobacterium Islandicum-Aw-1

The structure of Crystal Structure of Betaaspartyl Dipeptidase From Thermophilic Keratin Degrading Fervidobacterium Islandicum-Aw-1, PDB code: 7cdh was solved by I.Dhanasingh, J.W.La, D.W.Lee, S.H.Lee, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.85 / 2.60
Space group	I 4 2 2
Cell size a, b, c (Å), α, β, γ (°)	143.94, 143.94, 119.57, 90, 90, 90
R / Rfree (%)	16.3 / 22.3

The binding sites of Zinc atom in the Crystal Structure of Betaaspartyl Dipeptidase From Thermophilic Keratin Degrading Fervidobacterium Islandicum-Aw-1 (pdb code 7cdh). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Betaaspartyl Dipeptidase From Thermophilic Keratin Degrading Fervidobacterium Islandicum-Aw-1, PDB code: 7cdh:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Betaaspartyl Dipeptidase From Thermophilic Keratin Degrading Fervidobacterium Islandicum-Aw-1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Betaaspartyl Dipeptidase From Thermophilic Keratin Degrading Fervidobacterium Islandicum-Aw-1 within 5.0Å range: probe atom residue distance (Å) B Occ X:Zn410 b:50.8 occ:1.00 ND1 X:HIS195 2.1 28.2 1.0 OE1 X:GLU156 2.2 36.9 1.0 NE2 X:HIS224 2.3 49.7 1.0 O X:HOH516 2.8 62.3 1.0 CE1 X:HIS195 3.0 33.2 1.0 CD X:GLU156 3.1 43.7 1.0 CG X:HIS195 3.2 30.7 1.0 CD2 X:HIS224 3.2 43.9 1.0 ZN X:ZN411 3.2 44.2 1.0 OE2 X:GLU156 3.3 54.0 1.0 CE1 X:HIS224 3.3 41.2 1.0 OH X:TYR130 3.4 47.1 1.0 CB X:HIS195 3.6 32.7 1.0 O X:HOH636 4.1 53.8 1.0 CE1 X:TYR130 4.1 31.4 1.0 CZ X:TYR130 4.1 37.6 1.0 NE2 X:HIS195 4.2 28.8 1.0 OD2 X:ASP285 4.3 44.5 1.0 CD2 X:HIS195 4.3 31.1 1.0 NE2 X:HIS61 4.3 44.1 1.0 O X:HOH645 4.3 61.9 1.0 CG X:HIS224 4.4 44.9 1.0 CA X:HIS195 4.4 31.7 1.0 ND1 X:HIS224 4.4 44.7 1.0 CG X:GLU156 4.5 44.0 1.0 CE1 X:HIS61 4.5 50.3 1.0 CG2 X:THR223 4.7 36.5 1.0 OD1 X:ASP285 4.9 47.4 1.0 CG X:ASP285 4.9 40.2 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Betaaspartyl Dipeptidase From Thermophilic Keratin Degrading Fervidobacterium Islandicum-Aw-1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Betaaspartyl Dipeptidase From Thermophilic Keratin Degrading Fervidobacterium Islandicum-Aw-1 within 5.0Å range: probe atom residue distance (Å) B Occ X:Zn411 b:44.2 occ:1.00 OE2 X:GLU156 2.0 54.0 1.0 NE2 X:HIS61 2.1 44.1 1.0 NE2 X:HIS63 2.3 33.9 1.0 OD1 X:ASP285 2.4 47.4 1.0 CD X:GLU156 2.9 43.7 1.0 CE1 X:HIS61 3.0 50.3 1.0 O X:HOH516 3.0 62.3 1.0 CG X:ASP285 3.2 40.2 1.0 OE1 X:GLU156 3.2 36.9 1.0 CD2 X:HIS61 3.2 47.1 1.0 ZN X:ZN410 3.2 50.8 1.0 CE1 X:HIS63 3.2 35.4 1.0 OD2 X:ASP285 3.3 44.5 1.0 CD2 X:HIS63 3.3 36.4 1.0 ND1 X:HIS61 4.1 48.0 1.0 CG X:GLU156 4.3 44.0 1.0 CG X:HIS61 4.3 45.5 1.0 ND1 X:HIS63 4.4 31.4 1.0 CG X:HIS63 4.5 30.5 1.0 NE2 X:HIS224 4.5 49.7 1.0 CB X:ASP285 4.5 38.7 1.0 CE1 X:HIS224 4.7 41.2 1.0 SG X:CYS96 4.8 42.4 1.0 CA X:ASP285 4.9 35.5 1.0

J.W.La, I.Dhanasingh, H.Jang, S.H.Lee, D.W.Lee. Functional Characterization of Primordial Protein Repair Enzyme M38 Metallo-Peptidase From Fervidobacterium Islandicum Aw-1. Front Mol Biosci V. 7 00634 2020.
ISSN: ESSN 2296-889X
PubMed: 33392259
DOI: 10.3389/FMOLB.2020.600634