Zinc in PDB 7c17: The Cryo-Em Structure of E. Coli Cuer Transcription Activation Complex with Fully Duplex Promoter Dna

All present enzymatic activity of The Cryo-Em Structure of E. Coli Cuer Transcription Activation Complex with Fully Duplex Promoter Dna:
2.7.7.6;

The structure of The Cryo-Em Structure of E. Coli Cuer Transcription Activation Complex with Fully Duplex Promoter Dna also contains other interesting chemical elements:

Silver	(Ag)	1 atom
Magnesium	(Mg)	1 atom

The binding sites of Zinc atom in the The Cryo-Em Structure of E. Coli Cuer Transcription Activation Complex with Fully Duplex Promoter Dna (pdb code 7c17). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the The Cryo-Em Structure of E. Coli Cuer Transcription Activation Complex with Fully Duplex Promoter Dna, PDB code: 7c17:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the The Cryo-Em Structure of E. Coli Cuer Transcription Activation Complex with Fully Duplex Promoter Dna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of The Cryo-Em Structure of E. Coli Cuer Transcription Activation Complex with Fully Duplex Promoter Dna within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1501 b:62.3 occ:1.00 SG D:CYS72 2.8 73.0 1.0 SG D:CYS70 3.0 68.2 1.0 N D:CYS72 3.0 73.0 1.0 SG D:CYS88 3.0 63.3 1.0 N D:LEU71 3.1 64.1 1.0 CG1 D:VAL90 3.2 60.8 1.0 CB D:CYS70 3.5 68.2 1.0 CB D:LEU71 3.6 64.1 1.0 CA D:LEU71 3.7 64.1 1.0 SG D:CYS85 3.8 65.2 1.0 C D:LEU71 3.8 64.1 1.0 CB D:CYS72 3.8 73.0 1.0 CA D:CYS72 3.9 73.0 1.0 C D:CYS70 4.0 68.2 1.0 CA D:CYS70 4.3 68.2 1.0 CB D:CYS85 4.4 65.2 1.0 CB D:VAL90 4.4 60.8 1.0 N D:GLY73 4.4 70.1 1.0 C D:CYS72 4.7 73.0 1.0 CB D:CYS88 4.8 63.3 1.0 CG D:LEU71 4.9 64.1 1.0 N D:LYS74 5.0 60.5 1.0 O D:LEU71 5.0 64.1 1.0

Zinc binding site 2 out of 2 in the The Cryo-Em Structure of E. Coli Cuer Transcription Activation Complex with Fully Duplex Promoter Dna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of The Cryo-Em Structure of E. Coli Cuer Transcription Activation Complex with Fully Duplex Promoter Dna within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1502 b:86.4 occ:1.00 SG D:CYS898 2.5 56.0 1.0 SG D:CYS895 2.5 61.6 1.0 SG D:CYS888 2.5 58.9 1.0 SG D:CYS814 2.5 67.6 1.0 CB D:CYS895 2.8 61.6 1.0 CB D:CYS814 3.0 67.6 1.0 N D:CYS814 3.3 67.6 1.0 CB D:CYS898 3.5 56.0 1.0 CA D:CYS814 3.7 67.6 1.0 N D:CYS895 3.7 61.6 1.0 CA D:CYS895 3.9 61.6 1.0 CB D:CYS888 3.9 58.9 1.0 C D:ASP813 4.3 66.7 1.0 CA D:CYS888 4.5 58.9 1.0 O D:CYS814 4.5 67.6 1.0 C D:CYS814 4.5 67.6 1.0 CA D:ASP813 4.5 66.7 1.0 CG2 D:THR890 4.6 54.5 1.0 OD1 D:ASP813 4.7 66.7 1.0 N D:ASP889 4.8 60.8 1.0 C D:VAL894 4.8 56.8 1.0 C D:CYS895 4.9 61.6 1.0 CA D:CYS898 4.9 56.0 1.0

C.Fang, S.J.Philips, X.Wu, K.Chen, J.Shi, L.Shen, J.Xu, Y.Feng, T.V.O'halloran, Y.Zhang. Cuer Activates Transcription Through A Dna Distortion Mechanism. Nat.Chem.Biol. 2020.
ISSN: ESSN 1552-4469
PubMed: 32989300
DOI: 10.1038/S41589-020-00653-X