Zinc in PDB 7bv2: The NSP12-NSP7-NSP8 Complex Bound to the Template-Primer Rna and Triphosphate Form of Remdesivir(Rtp)

The structure of The NSP12-NSP7-NSP8 Complex Bound to the Template-Primer Rna and Triphosphate Form of Remdesivir(Rtp) also contains other interesting chemical elements:

Magnesium

(Mg)

3 atoms

The binding sites of Zinc atom in the The NSP12-NSP7-NSP8 Complex Bound to the Template-Primer Rna and Triphosphate Form of Remdesivir(Rtp) (pdb code 7bv2). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the The NSP12-NSP7-NSP8 Complex Bound to the Template-Primer Rna and Triphosphate Form of Remdesivir(Rtp), PDB code: 7bv2:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the The NSP12-NSP7-NSP8 Complex Bound to the Template-Primer Rna and Triphosphate Form of Remdesivir(Rtp)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of The NSP12-NSP7-NSP8 Complex Bound to the Template-Primer Rna and Triphosphate Form of Remdesivir(Rtp) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1001 b:42.1 occ:1.00 SG A:CYS310 2.3 18.6 1.0 SG A:CYS306 2.3 22.1 1.0 SG A:CYS301 2.4 22.9 1.0 ND1 A:HIS295 2.4 19.1 1.0 O A:CYS306 3.2 22.1 1.0 CE1 A:HIS295 3.3 19.1 1.0 CG A:HIS295 3.4 19.1 1.0 CB A:CYS301 3.5 22.9 1.0 CB A:CYS306 3.5 22.1 1.0 CB A:CYS310 3.6 18.6 1.0 C A:CYS306 3.7 22.1 1.0 CB A:HIS295 3.7 19.1 1.0 CA A:CYS301 3.9 22.9 1.0 CA A:CYS306 4.0 22.1 1.0 N A:HIS295 4.4 19.1 1.0 NE2 A:HIS295 4.5 19.1 1.0 N A:ILE307 4.5 19.2 1.0 CD2 A:HIS295 4.5 19.1 1.0 O A:THR293 4.6 21.9 1.0 N A:CYS310 4.7 18.6 1.0 CA A:HIS295 4.7 19.1 1.0 N A:CYS301 4.7 22.9 1.0 CA A:CYS310 4.7 18.6 1.0 N A:LEU302 4.9 23.2 1.0 CA A:ILE307 5.0 19.2 1.0 C A:CYS301 5.0 22.9 1.0

Zinc binding site 2 out of 2 in the The NSP12-NSP7-NSP8 Complex Bound to the Template-Primer Rna and Triphosphate Form of Remdesivir(Rtp)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of The NSP12-NSP7-NSP8 Complex Bound to the Template-Primer Rna and Triphosphate Form of Remdesivir(Rtp) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1002 b:38.8 occ:1.00 ND1 A:HIS642 2.2 22.1 1.0 SG A:CYS487 2.4 25.5 1.0 SG A:CYS646 2.4 23.4 1.0 SG A:CYS645 2.6 24.8 1.0 CG A:HIS642 3.1 22.1 1.0 CB A:HIS642 3.2 22.1 1.0 CE1 A:HIS642 3.3 22.1 1.0 CB A:CYS487 3.6 25.5 1.0 CB A:CYS645 3.7 24.8 1.0 CB A:CYS646 3.7 23.4 1.0 N A:CYS487 3.8 25.5 1.0 CE1 A:PHE571 4.0 21.8 1.0 N A:CYS646 4.0 23.4 1.0 CA A:HIS642 4.1 22.1 1.0 C A:CYS645 4.1 24.8 1.0 CA A:CYS487 4.2 25.5 1.0 CD2 A:HIS642 4.3 22.1 1.0 NE2 A:HIS642 4.3 22.1 1.0 CA A:CYS646 4.4 23.4 1.0 C A:GLY486 4.4 22.8 1.0 CA A:CYS645 4.5 24.8 1.0 O A:CYS645 4.5 24.8 1.0 CA A:GLY486 4.5 22.8 1.0 CD1 A:PHE571 4.5 21.8 1.0 O A:HIS642 4.6 22.1 1.0 CZ A:PHE571 4.7 21.8 1.0 NZ A:LYS532 4.7 22.4 1.0 C A:HIS642 4.8 22.1 1.0 CE A:LYS532 5.0 22.4 1.0

W.Yin, C.Mao, X.Luan, D.Shen, Q.Shen, H.Su, X.Wang, F.Zhou, W.Zhao, M.Gao, S.Chang, Y.C.Xie, G.Tian, H.W.Jiang, S.C.Tao, J.Shen, Y.Jiang, H.Jiang, Y.Xu, S.Zhang, Y.Zhang, H.E.Xu. The NSP12-NSP7-NSP8 Complex Bound to the Template-Primer Rna and Triphosphate Form of Remdesivir(Rtp) To Be Published.