Atomistry » Zinc » PDB 7auw-7b83 » 7b5s
Atomistry »
  Zinc »
    PDB 7auw-7b83 »
      7b5s »

Zinc in PDB 7b5s: Ubiquitin Ligation to F-Box Protein Substrates By Scf-Rbr E3-E3 Super- Assembly: CUL1-RBX1-ARIH1 Ariadne. Transition State 1

Enzymatic activity of Ubiquitin Ligation to F-Box Protein Substrates By Scf-Rbr E3-E3 Super- Assembly: CUL1-RBX1-ARIH1 Ariadne. Transition State 1

All present enzymatic activity of Ubiquitin Ligation to F-Box Protein Substrates By Scf-Rbr E3-E3 Super- Assembly: CUL1-RBX1-ARIH1 Ariadne. Transition State 1:
2.3.2.27; 2.3.2.31; 2.3.2.32;

Zinc Binding Sites:

The binding sites of Zinc atom in the Ubiquitin Ligation to F-Box Protein Substrates By Scf-Rbr E3-E3 Super- Assembly: CUL1-RBX1-ARIH1 Ariadne. Transition State 1 (pdb code 7b5s). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 5 binding sites of Zinc where determined in the Ubiquitin Ligation to F-Box Protein Substrates By Scf-Rbr E3-E3 Super- Assembly: CUL1-RBX1-ARIH1 Ariadne. Transition State 1, PDB code: 7b5s:
Jump to Zinc binding site number: 1; 2; 3; 4; 5;

Zinc binding site 1 out of 5 in 7b5s

Go back to Zinc Binding Sites List in 7b5s
Zinc binding site 1 out of 5 in the Ubiquitin Ligation to F-Box Protein Substrates By Scf-Rbr E3-E3 Super- Assembly: CUL1-RBX1-ARIH1 Ariadne. Transition State 1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Ubiquitin Ligation to F-Box Protein Substrates By Scf-Rbr E3-E3 Super- Assembly: CUL1-RBX1-ARIH1 Ariadne. Transition State 1 within 5.0Å range:
probe atom residue distance (Å) B Occ
H:Zn601

b:206.8
occ:1.00
 SG H:CYS297 2.3 131.4 1.0
SG H:CYS281 2.3 135.4 1.0
SG H:CYS299 2.3 133.4 1.0
SG H:CYS276 2.3 117.2 1.0
CB H:CYS297 3.0 131.4 1.0
CB H:CYS281 3.1 135.4 1.0
CB H:CYS276 3.2 117.2 1.0
CB H:CYS299 3.3 133.4 1.0
CB H:ALA278 4.2 122.2 1.0
ND1 H:HIS283 4.3 129.1 1.0
O H:CYS297 4.3 131.4 1.0
CA H:CYS297 4.4 131.4 1.0
CA H:CYS281 4.5 135.4 1.0
CA H:CYS299 4.6 133.4 1.0
C H:CYS297 4.6 131.4 1.0
N H:CYS299 4.6 133.4 1.0
CA H:CYS276 4.7 117.2 1.0
CB H:HIS283 4.7 129.1 1.0
CG H:HIS283 4.8 129.1 1.0

Zinc binding site 2 out of 5 in 7b5s

Go back to Zinc Binding Sites List in 7b5s
Zinc binding site 2 out of 5 in the Ubiquitin Ligation to F-Box Protein Substrates By Scf-Rbr E3-E3 Super- Assembly: CUL1-RBX1-ARIH1 Ariadne. Transition State 1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Ubiquitin Ligation to F-Box Protein Substrates By Scf-Rbr E3-E3 Super- Assembly: CUL1-RBX1-ARIH1 Ariadne. Transition State 1 within 5.0Å range:
probe atom residue distance (Å) B Occ
H:Zn602

b:131.7
occ:1.00
 NE2 H:HIS312 2.1 67.9 1.0
SG H:CYS307 2.3 95.3 1.0
SG H:CYS304 2.3 100.3 1.0
SG H:CYS317 2.3 71.0 1.0
CE1 H:HIS312 3.0 67.9 1.0
CD2 H:HIS312 3.1 67.9 1.0
CB H:CYS307 3.5 95.3 1.0
CB H:CYS317 3.7 71.0 1.0
CB H:CYS304 3.9 100.3 1.0
ND1 H:HIS312 4.1 67.9 1.0
CG H:HIS312 4.2 67.9 1.0
N H:CYS307 4.2 95.3 1.0
CA H:CYS317 4.4 71.0 1.0
CA H:CYS307 4.4 95.3 1.0
N H:GLY308 4.6 93.6 1.0
O H:GLU309 4.9 88.2 1.0
OE1 H:GLU309 4.9 88.2 1.0
O H:ASN310 4.9 81.4 1.0
N H:GLU309 5.0 88.2 1.0

Zinc binding site 3 out of 5 in 7b5s

Go back to Zinc Binding Sites List in 7b5s
Zinc binding site 3 out of 5 in the Ubiquitin Ligation to F-Box Protein Substrates By Scf-Rbr E3-E3 Super- Assembly: CUL1-RBX1-ARIH1 Ariadne. Transition State 1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Ubiquitin Ligation to F-Box Protein Substrates By Scf-Rbr E3-E3 Super- Assembly: CUL1-RBX1-ARIH1 Ariadne. Transition State 1 within 5.0Å range:
probe atom residue distance (Å) B Occ
R:Zn201

b:65.2
occ:1.00
 ND1 R:HIS80 2.0 51.1 1.0
SG R:CYS42 2.3 46.9 1.0
SG R:CYS45 2.3 43.8 1.0
SG R:CYS83 2.3 53.1 1.0
CG R:HIS80 2.8 51.1 1.0
CE1 R:HIS80 2.9 51.1 1.0
CB R:HIS80 3.3 51.1 1.0
CB R:CYS42 3.4 46.9 1.0
CB R:CYS83 3.7 53.1 1.0
CB R:CYS45 3.8 43.8 1.0
NE2 R:HIS80 3.8 51.1 1.0
CD2 R:HIS80 3.8 51.1 1.0
N R:CYS45 4.1 43.8 1.0
N R:HIS80 4.2 51.1 1.0
CB R:CYS53 4.2 58.5 1.0
CA R:HIS80 4.4 51.1 1.0
CA R:CYS45 4.5 43.8 1.0
CA R:CYS53 4.6 58.5 1.0
CB R:ILE44 4.7 42.9 1.0
CA R:CYS42 4.8 46.9 1.0
O R:CYS42 4.9 46.9 1.0

Zinc binding site 4 out of 5 in 7b5s

Go back to Zinc Binding Sites List in 7b5s
Zinc binding site 4 out of 5 in the Ubiquitin Ligation to F-Box Protein Substrates By Scf-Rbr E3-E3 Super- Assembly: CUL1-RBX1-ARIH1 Ariadne. Transition State 1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Ubiquitin Ligation to F-Box Protein Substrates By Scf-Rbr E3-E3 Super- Assembly: CUL1-RBX1-ARIH1 Ariadne. Transition State 1 within 5.0Å range:
probe atom residue distance (Å) B Occ
R:Zn202

b:105.7
occ:1.00
 OD2 R:ASP97 2.0 81.0 1.0
ND1 R:HIS77 2.0 67.0 1.0
SG R:CYS75 2.3 75.1 1.0
SG R:CYS94 2.3 70.7 1.0
CG R:ASP97 2.7 81.0 1.0
OD1 R:ASP97 2.8 81.0 1.0
CE1 R:HIS77 2.8 67.0 1.0
CG R:HIS77 3.2 67.0 1.0
CB R:CYS94 3.5 70.7 1.0
CB R:CYS75 3.6 75.1 1.0
CB R:HIS77 3.7 67.0 1.0
NE2 R:HIS77 4.0 67.0 1.0
CB R:ASP97 4.1 81.0 1.0
CD2 R:HIS77 4.2 67.0 1.0
CZ3 R:TRP101 4.5 69.7 1.0
CE3 R:TRP101 4.5 69.7 1.0
CA R:CYS94 4.8 70.7 1.0
CA R:CYS75 4.8 75.1 1.0
O R:CYS75 4.8 75.1 1.0
C R:CYS75 4.9 75.1 1.0
CA R:HIS77 4.9 67.0 1.0
N R:HIS77 5.0 67.0 1.0
N R:ASP97 5.0 81.0 1.0

Zinc binding site 5 out of 5 in 7b5s

Go back to Zinc Binding Sites List in 7b5s
Zinc binding site 5 out of 5 in the Ubiquitin Ligation to F-Box Protein Substrates By Scf-Rbr E3-E3 Super- Assembly: CUL1-RBX1-ARIH1 Ariadne. Transition State 1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Ubiquitin Ligation to F-Box Protein Substrates By Scf-Rbr E3-E3 Super- Assembly: CUL1-RBX1-ARIH1 Ariadne. Transition State 1 within 5.0Å range:
probe atom residue distance (Å) B Occ
R:Zn203

b:102.7
occ:1.00
 ND1 R:HIS82 2.0 57.2 1.0
SG R:CYS53 2.3 58.5 1.0
SG R:CYS68 2.3 65.6 1.0
SG R:CYS56 2.3 61.7 1.0
CE1 R:HIS82 2.7 57.2 1.0
CB R:CYS68 3.0 65.6 1.0
CG R:HIS82 3.2 57.2 1.0
CB R:CYS56 3.3 61.7 1.0
CB R:CYS53 3.4 58.5 1.0
CB R:HIS82 3.8 57.2 1.0
N R:CYS56 3.9 61.7 1.0
NE2 R:HIS82 4.0 57.2 1.0
CA R:CYS68 4.0 65.6 1.0
N R:CYS53 4.1 58.5 1.0
CA R:CYS56 4.2 61.7 1.0
CD2 R:HIS82 4.2 57.2 1.0
CA R:CYS53 4.3 58.5 1.0
CB R:GLU55 4.9 58.7 1.0
N R:CYS68 5.0 65.6 1.0
N R:HIS82 5.0 57.2 1.0
C R:CYS53 5.0 58.5 1.0
C R:GLU55 5.0 58.7 1.0

Reference:

D.Horn-Ghetko, D.T.Krist, J.R.Prabu, B.Kheewong, M.M.P.C.Mulder, D.C.Scott, M.Klugel, H.Ovaa, G.Kleiger, B.Schulman. Ubiquitin Ligation to F-Box Protein Targets By Scf-Rbr E3-E3 Super-Assembly Nature 2021.
ISSN: ESSN 1476-4687
DOI: 10.1038/S41586-021-03197-9
Page generated: Tue Oct 29 17:27:14 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy