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Zinc in PDB 7b4d: Structural Basis of Reactivation of Oncogenic P53 Mutants By A Small Molecule: Methylene Quinuclidinone (Mq). Human P53DBD-R273C/S240R Double Mutant Bound to Dna and Mq: R273C/S240R-Dna-MqProtein crystallography data
The structure of Structural Basis of Reactivation of Oncogenic P53 Mutants By A Small Molecule: Methylene Quinuclidinone (Mq). Human P53DBD-R273C/S240R Double Mutant Bound to Dna and Mq: R273C/S240R-Dna-Mq, PDB code: 7b4d
was solved by
H.Rozenberg,
Y.Diskin-Posner,
O.Degtjarik,
Z.Shakked,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Structural Basis of Reactivation of Oncogenic P53 Mutants By A Small Molecule: Methylene Quinuclidinone (Mq). Human P53DBD-R273C/S240R Double Mutant Bound to Dna and Mq: R273C/S240R-Dna-Mq
(pdb code 7b4d). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structural Basis of Reactivation of Oncogenic P53 Mutants By A Small Molecule: Methylene Quinuclidinone (Mq). Human P53DBD-R273C/S240R Double Mutant Bound to Dna and Mq: R273C/S240R-Dna-Mq, PDB code: 7b4d: Zinc binding site 1 out of 1 in 7b4dGo back to Zinc Binding Sites List in 7b4d
Zinc binding site 1 out
of 1 in the Structural Basis of Reactivation of Oncogenic P53 Mutants By A Small Molecule: Methylene Quinuclidinone (Mq). Human P53DBD-R273C/S240R Double Mutant Bound to Dna and Mq: R273C/S240R-Dna-Mq
Mono view Stereo pair view
Reference:
O.Degtjarik,
D.Golovenko,
Y.Diskin-Posner,
L.Abrahmsen,
H.Rozenberg,
Z.Shakked.
P53 Structure 7 To Be Published.
Page generated: Fri Dec 17 11:45:57 2021
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