Zinc in PDB 6yhr: Crystal Structure of Werner Syndrome Helicase

All present enzymatic activity of Crystal Structure of Werner Syndrome Helicase:
3.6.4.12;

The structure of Crystal Structure of Werner Syndrome Helicase, PDB code: 6yhr was solved by J.A.Newman, A.E.Gavard, P.Savitsky, F.Von Delft, C.H.Arrowsmith, A.Edwards, C.Bountra, O.Gileadi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	69.12 / 2.20
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	54.595, 90.627, 138.233, 90.00, 90.00, 90.00
R / Rfree (%)	19.7 / 23.6

The binding sites of Zinc atom in the Crystal Structure of Werner Syndrome Helicase (pdb code 6yhr). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Werner Syndrome Helicase, PDB code: 6yhr:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Werner Syndrome Helicase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Werner Syndrome Helicase within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1202 b:57.6 occ:1.00 SG A:CYS935 2.3 51.6 1.0 SG A:CYS908 2.4 52.9 1.0 SG A:CYS939 2.4 62.2 1.0 SG A:CYS936 2.4 54.1 1.0 CB A:CYS939 3.3 63.4 1.0 CB A:CYS935 3.4 43.8 1.0 CB A:CYS908 3.4 57.9 1.0 CB A:CYS936 3.4 47.3 1.0 N A:CYS936 3.7 47.1 1.0 CA A:CYS908 3.8 57.5 1.0 C A:CYS935 4.1 54.0 1.0 CA A:CYS936 4.1 47.2 1.0 N A:ARG909 4.2 56.4 1.0 N A:CYS939 4.3 52.2 1.0 N A:ARG910 4.4 53.0 1.0 C A:CYS908 4.4 49.9 1.0 CA A:CYS935 4.4 60.1 1.0 CA A:CYS939 4.4 58.9 1.0 CB A:ARG910 4.4 52.2 1.0 N A:GLY931 4.5 66.9 1.0 O A:CYS935 4.8 49.5 1.0 C A:CYS936 4.8 52.6 1.0 CA A:MET930 4.8 66.5 1.0 O A:CYS936 4.9 56.2 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Werner Syndrome Helicase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Werner Syndrome Helicase within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1203 b:48.5 occ:1.00 NE2 A:HIS558 2.1 51.4 1.0 OE1 A:GLU563 2.3 46.5 1.0 CE1 A:HIS558 3.0 56.7 1.0 CD A:GLU563 3.1 50.2 1.0 CD2 A:HIS558 3.2 57.6 1.0 CG A:GLU563 3.3 50.2 1.0 ND1 A:HIS558 4.1 46.9 1.0 CD A:PRO530 4.2 57.3 1.0 CG A:HIS558 4.2 55.6 1.0 OE2 A:GLU563 4.3 63.4 1.0 CG A:PRO530 4.7 47.1 1.0 CB A:GLU563 4.7 41.0 1.0 CB A:GLU562 4.9 47.0 1.0

J.A.Newman, A.E.Gavard, P.Savitsky, F.Von Delft, C.H.Arrowsmith, A.Edwards, C.Bountra, O.Gileadi. Crystal Structure of Werner Syndrome Helicase To Be Published.