Zinc in PDB 6wmt: F. Tularensis RNAPS70-(Mgla-Sspa)-Ppgpp-Pigr-Igla Dna Complex

All present enzymatic activity of F. Tularensis RNAPS70-(Mgla-Sspa)-Ppgpp-Pigr-Igla Dna Complex:
2.7.7.6;

The structure of F. Tularensis RNAPS70-(Mgla-Sspa)-Ppgpp-Pigr-Igla Dna Complex also contains other interesting chemical elements:

Magnesium

(Mg)

2 atoms

The binding sites of Zinc atom in the F. Tularensis RNAPS70-(Mgla-Sspa)-Ppgpp-Pigr-Igla Dna Complex (pdb code 6wmt). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the F. Tularensis RNAPS70-(Mgla-Sspa)-Ppgpp-Pigr-Igla Dna Complex, PDB code: 6wmt:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the F. Tularensis RNAPS70-(Mgla-Sspa)-Ppgpp-Pigr-Igla Dna Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of F. Tularensis RNAPS70-(Mgla-Sspa)-Ppgpp-Pigr-Igla Dna Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1702 b:0.8 occ:1.00 CB D:CYS70 2.9 0.7 1.0 CB D:CYS68 3.0 0.5 1.0 SG D:CYS86 3.1 0.1 1.0 SG D:CYS83 3.2 0.7 1.0 SG D:CYS68 3.2 0.5 1.0 N D:CYS70 3.4 0.7 1.0 CB D:CYS83 3.5 0.7 1.0 CA D:CYS70 3.7 0.7 1.0 CB D:CYS86 3.9 0.1 1.0 N D:LEU69 4.1 98.0 1.0 N D:GLY71 4.1 99.4 1.0 CA D:CYS68 4.1 0.5 1.0 C D:CYS68 4.2 0.5 1.0 C D:CYS70 4.4 0.7 1.0 N D:CYS86 4.4 0.1 1.0 SG D:CYS70 4.4 0.7 1.0 C D:LEU69 4.5 98.0 1.0 N D:LYS72 4.7 0.2 1.0 CA D:CYS86 4.7 0.1 1.0 CB D:ARG85 4.7 0.0 1.0 CA D:LEU69 4.9 98.0 1.0 CD2 D:TYR73 4.9 0.3 1.0 O D:CYS68 4.9 0.5 1.0 CB D:LYS72 4.9 0.2 1.0

Zinc binding site 2 out of 2 in the F. Tularensis RNAPS70-(Mgla-Sspa)-Ppgpp-Pigr-Igla Dna Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of F. Tularensis RNAPS70-(Mgla-Sspa)-Ppgpp-Pigr-Igla Dna Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1703 b:0.7 occ:1.00 CB D:CYS811 2.8 0.2 1.0 CB D:CYS884 3.0 0.2 1.0 CB D:CYS891 3.1 0.5 1.0 SG D:CYS884 3.1 0.2 1.0 SG D:CYS891 3.2 0.5 1.0 SG D:CYS894 3.3 99.8 1.0 N D:CYS891 3.3 0.5 1.0 CA D:CYS884 3.4 0.2 1.0 SG D:CYS811 3.4 0.2 1.0 CG2 D:THR886 3.5 0.5 1.0 CA D:CYS891 3.8 0.5 1.0 N D:LYS885 3.9 0.5 1.0 CB D:CYS894 3.9 99.8 1.0 C D:CYS884 4.0 0.2 1.0 CA D:CYS811 4.1 0.2 1.0 N D:THR886 4.3 0.5 1.0 N D:CYS811 4.3 0.2 1.0 C D:LEU890 4.5 98.7 1.0 CB D:THR886 4.5 0.5 1.0 N D:CYS884 4.7 0.2 1.0 C D:CYS891 4.7 0.5 1.0 O D:CYS891 4.8 0.5 1.0 CA D:LEU890 4.8 98.7 1.0

B.A.Travis, K.M.Ramsey, S.M.Prezioso, T.Tallo, J.M.Wandzilak, A.Hsu, M.Borgnia, A.Bartesaghi, S.L.Dove, R.G.Brennan, M.A.Schumacher. Structural Basis For Virulence Activation of Francisella Tularensis. Mol.Cell 2020.
ISSN: ISSN 1097-2765
PubMed: 33217319
DOI: 10.1016/J.MOLCEL.2020.10.035