Zinc in PDB 6w61: Crystal Structure of the Methyltransferase-Stimulatory Factor Complex of NSP16 and NSP10 From Sars Cov-2.

The structure of Crystal Structure of the Methyltransferase-Stimulatory Factor Complex of NSP16 and NSP10 From Sars Cov-2., PDB code: 6w61 was solved by Y.Kim, R.Jedrzejczak, N.Maltseva, M.Endres, A.Godzik, A.Joachimiak, Centerfor Structural Genomics Of Infectious Diseases (Csgid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.33 / 2.00
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	168.564, 168.564, 51.962, 90.00, 90.00, 120.00
R / Rfree (%)	17.1 / 19.3

The structure of Crystal Structure of the Methyltransferase-Stimulatory Factor Complex of NSP16 and NSP10 From Sars Cov-2. also contains other interesting chemical elements:

Chlorine

(Cl)

1 atom

The binding sites of Zinc atom in the Crystal Structure of the Methyltransferase-Stimulatory Factor Complex of NSP16 and NSP10 From Sars Cov-2. (pdb code 6w61). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of the Methyltransferase-Stimulatory Factor Complex of NSP16 and NSP10 From Sars Cov-2., PDB code: 6w61:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of the Methyltransferase-Stimulatory Factor Complex of NSP16 and NSP10 From Sars Cov-2.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Methyltransferase-Stimulatory Factor Complex of NSP16 and NSP10 From Sars Cov-2. within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn4402 b:90.3 occ:1.00 SG B:CYS4381 2.4 81.1 1.0 SG B:CYS4373 2.4 90.4 1.0 SG B:CYS4383 2.4 95.9 1.0 SG B:CYS4370 2.4 86.8 1.0 CB B:CYS4370 3.2 81.1 1.0 CB B:CYS4383 3.4 0.2 1.0 CB B:CYS4373 3.4 93.6 1.0 CB B:CYS4381 3.5 83.7 1.0 N B:CYS4373 3.7 99.6 1.0 N B:CYS4383 4.1 0.6 1.0 CA B:CYS4381 4.2 84.5 1.0 CA B:CYS4373 4.2 93.5 1.0 CA B:CYS4383 4.3 0.3 1.0 CB B:VAL4372 4.4 0.8 1.0 N B:SER4382 4.6 87.0 1.0 CA B:CYS4370 4.7 82.1 1.0 C B:CYS4381 4.7 84.0 1.0 C B:VAL4372 4.8 0.1 1.0 N B:VAL4372 4.9 0.3 1.0 N B:GLY4374 4.9 80.2 1.0 CA B:VAL4372 4.9 0.2 1.0 C B:CYS4373 5.0 84.0 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of the Methyltransferase-Stimulatory Factor Complex of NSP16 and NSP10 From Sars Cov-2.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of the Methyltransferase-Stimulatory Factor Complex of NSP16 and NSP10 From Sars Cov-2. within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn4403 b:58.5 occ:1.00 NE2 B:HIS4336 2.1 71.7 1.0 SG B:CYS4327 2.3 55.2 1.0 SG B:CYS4330 2.4 60.5 1.0 SG B:CYS4343 2.4 57.6 1.0 CE1 B:HIS4336 3.1 63.3 1.0 CB B:CYS4327 3.1 55.0 1.0 CD2 B:HIS4336 3.1 67.9 1.0 CB B:CYS4343 3.4 62.7 1.0 CB B:CYS4330 3.4 59.2 1.0 N B:CYS4330 3.6 53.3 1.0 CA B:CYS4330 4.0 54.5 1.0 ND1 B:HIS4336 4.2 74.4 1.0 CG B:HIS4336 4.3 74.8 1.0 O B:HOH4523 4.3 78.3 1.0 CA B:CYS4343 4.5 69.7 1.0 C B:TYR4329 4.5 59.8 1.0 CA B:CYS4327 4.6 52.0 1.0 CB B:TYR4329 4.7 57.2 1.0 CB B:LYS4346 4.9 70.0 1.0 C B:CYS4327 5.0 52.5 1.0 CA B:TYR4329 5.0 56.6 1.0

Y.Kim, R.Jedrzejczak, N.Maltseva, M.Endres, A.Godzik, A.Joachimiak, Center For Structural Genomics Of Infectious Diseases(Csgid). Crystal Structure of the Methyltransferase-Stimulatory Factor Complex of NSP16 and NSP10 From Sars Cov-2. To Be Published.