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Zinc in PDB 6u4t: Carbonic Anhydrase 9 in Complex with SB4197Enzymatic activity of Carbonic Anhydrase 9 in Complex with SB4197
All present enzymatic activity of Carbonic Anhydrase 9 in Complex with SB4197:
4.2.1.1; Protein crystallography data
The structure of Carbonic Anhydrase 9 in Complex with SB4197, PDB code: 6u4t
was solved by
A.B.Murray,
C.L.Lomelino,
R.Mckenna,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Carbonic Anhydrase 9 in Complex with SB4197
(pdb code 6u4t). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Carbonic Anhydrase 9 in Complex with SB4197, PDB code: 6u4t: Zinc binding site 1 out of 1 in 6u4tGo back to Zinc Binding Sites List in 6u4t
Zinc binding site 1 out
of 1 in the Carbonic Anhydrase 9 in Complex with SB4197
Mono view Stereo pair view
Reference:
S.Bua,
C.Lomelino,
A.B.Murray,
S.M.Osman,
Z.A.Alothman,
M.Bozdag,
H.A.Abdel-Aziz,
W.M.Eldehna,
R.Mckenna,
A.Nocentini,
C.T.Supuran.
"A Sweet Combination": Developing Saccharin and Acesulfame K Structures For Selectively Targeting the Tumor-Associated Carbonic Anhydrases IX and XII. J.Med.Chem. V. 63 321 2020.
Page generated: Wed Dec 16 12:57:09 2020
ISSN: ISSN 0022-2623 PubMed: 31794211 DOI: 10.1021/ACS.JMEDCHEM.9B01669 |
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