Zinc in PDB 6sqo: Crystal Structure of Human MDM2 Ring Domain Homodimer Bound to UBCH5B- Ub
Enzymatic activity of Crystal Structure of Human MDM2 Ring Domain Homodimer Bound to UBCH5B- Ub
All present enzymatic activity of Crystal Structure of Human MDM2 Ring Domain Homodimer Bound to UBCH5B- Ub:
2.3.2.23; 2.3.2.24; 2.3.2.27;
2.3.2.23; 2.3.2.24; 2.3.2.27;
Protein crystallography data
The structure of Crystal Structure of Human MDM2 Ring Domain Homodimer Bound to UBCH5B- Ub, PDB code: 6sqo
was solved by
H.M.Magnussen,
S.F.Ahmed,
D.T.Huang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 112.00 / 1.41 |
| Space group | P 61 |
| Cell size a, b, c (Å), α, β, γ (°) | 129.709, 129.709, 70.537, 90.00, 90.00, 120.00 |
| R / Rfree (%) | 13.9 / 17.3 |
Other elements in 6sqo:
The structure of Crystal Structure of Human MDM2 Ring Domain Homodimer Bound to UBCH5B- Ub also contains other interesting chemical elements:
| Chlorine | (Cl) | 4 atoms |
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Human MDM2 Ring Domain Homodimer Bound to UBCH5B- Ub
(pdb code 6sqo). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Crystal Structure of Human MDM2 Ring Domain Homodimer Bound to UBCH5B- Ub, PDB code: 6sqo:
Jump to Zinc binding site number: 1; 2; 3; 4;
In total 4 binding sites of Zinc where determined in the Crystal Structure of Human MDM2 Ring Domain Homodimer Bound to UBCH5B- Ub, PDB code: 6sqo:
Jump to Zinc binding site number: 1; 2; 3; 4;
Zinc binding site 1 out of 4 in 6sqo
Go back to
Zinc Binding Sites List in 6sqo
Zinc binding site 1 out
of 4 in the Crystal Structure of Human MDM2 Ring Domain Homodimer Bound to UBCH5B- Ub
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Crystal Structure of Human MDM2 Ring Domain Homodimer Bound to UBCH5B- Ub within 5.0Å range:
|
Zinc binding site 2 out of 4 in 6sqo
Go back to
Zinc Binding Sites List in 6sqo
Zinc binding site 2 out
of 4 in the Crystal Structure of Human MDM2 Ring Domain Homodimer Bound to UBCH5B- Ub
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Crystal Structure of Human MDM2 Ring Domain Homodimer Bound to UBCH5B- Ub within 5.0Å range:
|
Zinc binding site 3 out of 4 in 6sqo
Go back to
Zinc Binding Sites List in 6sqo
Zinc binding site 3 out
of 4 in the Crystal Structure of Human MDM2 Ring Domain Homodimer Bound to UBCH5B- Ub
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of Crystal Structure of Human MDM2 Ring Domain Homodimer Bound to UBCH5B- Ub within 5.0Å range:
|
Zinc binding site 4 out of 4 in 6sqo
Go back to
Zinc Binding Sites List in 6sqo
Zinc binding site 4 out
of 4 in the Crystal Structure of Human MDM2 Ring Domain Homodimer Bound to UBCH5B- Ub
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of Crystal Structure of Human MDM2 Ring Domain Homodimer Bound to UBCH5B- Ub within 5.0Å range:
|
Reference:
H.M.Magnussen,
S.F.Ahmed,
G.J.Sibbet,
V.A.Hristova,
K.Nomura,
A.K.Hock,
L.J.Archibald,
A.G.Jamieson,
D.Fushman,
K.H.Vousden,
A.M.Weissman,
D.T.Huang.
Structural Basis For Dna Damage-Induced Phosphoregulation of MDM2 Ring Domain Nat Commun 2020.
ISSN: ESSN 2041-1723
Page generated: Wed Dec 16 12:49:38 2020
ISSN: ESSN 2041-1723
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