Zinc in PDB 6skv: Crystal Structure of Bovine Carbonic Anhydrase II in Complex with A Benzenesulfonamide-Based Ligand (SH2)

Enzymatic activity of Crystal Structure of Bovine Carbonic Anhydrase II in Complex with A Benzenesulfonamide-Based Ligand (SH2)

All present enzymatic activity of Crystal Structure of Bovine Carbonic Anhydrase II in Complex with A Benzenesulfonamide-Based Ligand (SH2):
4.2.1.1;

Protein crystallography data

The structure of Crystal Structure of Bovine Carbonic Anhydrase II in Complex with A Benzenesulfonamide-Based Ligand (SH2), PDB code: 6skv was solved by M.R.Groves, W.Wang, N.Van Oosterwijk, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 42.30 / 1.75
Space group P 32 2 1
Cell size a, b, c (Å), α, β, γ (°) 67.308, 67.308, 122.948, 90.00, 90.00, 120.00
R / Rfree (%) 17.1 / 18.9

Other elements in 6skv:

The structure of Crystal Structure of Bovine Carbonic Anhydrase II in Complex with A Benzenesulfonamide-Based Ligand (SH2) also contains other interesting chemical elements:

Copper (Cu) 3 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of Bovine Carbonic Anhydrase II in Complex with A Benzenesulfonamide-Based Ligand (SH2) (pdb code 6skv). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Bovine Carbonic Anhydrase II in Complex with A Benzenesulfonamide-Based Ligand (SH2), PDB code: 6skv:

Zinc binding site 1 out of 1 in 6skv

Go back to Zinc Binding Sites List in 6skv
Zinc binding site 1 out of 1 in the Crystal Structure of Bovine Carbonic Anhydrase II in Complex with A Benzenesulfonamide-Based Ligand (SH2)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Bovine Carbonic Anhydrase II in Complex with A Benzenesulfonamide-Based Ligand (SH2) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1000

b:24.7
occ:1.00
N1 A:E5Z1006 1.9 25.0 1.0
NE2 A:HIS94 2.0 24.7 1.0
ND1 A:HIS119 2.0 23.3 1.0
NE2 A:HIS96 2.1 23.8 1.0
CE1 A:HIS119 2.9 23.4 1.0
O2 A:E5Z1006 3.0 24.5 1.0
CD2 A:HIS94 3.0 26.2 1.0
CD2 A:HIS96 3.0 24.2 1.0
S1 A:E5Z1006 3.0 26.0 1.0
CE1 A:HIS94 3.1 26.3 1.0
CE1 A:HIS96 3.1 25.3 1.0
CG A:HIS119 3.1 23.3 1.0
CB A:HIS119 3.6 23.4 1.0
OG1 A:THR198 3.8 25.0 1.0
O1 A:E5Z1006 4.1 25.2 1.0
NE2 A:HIS119 4.1 23.2 1.0
OE1 A:GLU106 4.1 25.0 1.0
CG A:HIS94 4.1 25.8 1.0
ND1 A:HIS94 4.1 25.7 1.0
C1 A:E5Z1006 4.2 26.8 1.0
CG A:HIS96 4.2 24.2 1.0
CD2 A:HIS119 4.2 23.5 1.0
ND1 A:HIS96 4.2 25.1 1.0
C1 A:GOL1005 4.5 46.4 1.0
C2 A:E5Z1006 4.9 27.6 1.0
C6 A:E5Z1006 4.9 27.9 1.0

Reference:

M.R.Groves, W.Wang, N.Van Oosterwijk, M.Witte, J.Lohse. Target Diazotransfer Reagents to Label Metalloenzymes To Be Published.
Page generated: Wed Dec 16 12:48:54 2020

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