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Zinc in PDB 6sgp: X-Ray Structure of Human Glutamate Carboxypeptidase II (Gcpii) - the E424M Inactive Mutant, in Complex with A Sulfamide Inhibitor Gluglu
Enzymatic activity of X-Ray Structure of Human Glutamate Carboxypeptidase II (Gcpii) - the E424M Inactive Mutant, in Complex with A Sulfamide Inhibitor Gluglu
All present enzymatic activity of X-Ray Structure of Human Glutamate Carboxypeptidase II (Gcpii) - the E424M Inactive Mutant, in Complex with A Sulfamide Inhibitor Gluglu:
3.4.17.21;
3.4.17.21;
Protein crystallography data
The structure of X-Ray Structure of Human Glutamate Carboxypeptidase II (Gcpii) - the E424M Inactive Mutant, in Complex with A Sulfamide Inhibitor Gluglu, PDB code: 6sgp
was solved by
C.Barinka,
S.Shukla,
L.Motlova,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 46.90 / 1.58 |
| Space group | I 2 2 2 |
| Cell size a, b, c (Å), α, β, γ (°) | 101.349, 130.394, 158.538, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 18 / 20.1 |
Other elements in 6sgp:
The structure of X-Ray Structure of Human Glutamate Carboxypeptidase II (Gcpii) - the E424M Inactive Mutant, in Complex with A Sulfamide Inhibitor Gluglu also contains other interesting chemical elements:
| Calcium | (Ca) | 1 atom |
| Chlorine | (Cl) | 1 atom |
| Sodium | (Na) | 1 atom |
Zinc Binding Sites:
The binding sites of Zinc atom in the X-Ray Structure of Human Glutamate Carboxypeptidase II (Gcpii) - the E424M Inactive Mutant, in Complex with A Sulfamide Inhibitor Gluglu
(pdb code 6sgp). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the X-Ray Structure of Human Glutamate Carboxypeptidase II (Gcpii) - the E424M Inactive Mutant, in Complex with A Sulfamide Inhibitor Gluglu, PDB code: 6sgp:
Jump to Zinc binding site number: 1; 2;
In total 2 binding sites of Zinc where determined in the X-Ray Structure of Human Glutamate Carboxypeptidase II (Gcpii) - the E424M Inactive Mutant, in Complex with A Sulfamide Inhibitor Gluglu, PDB code: 6sgp:
Jump to Zinc binding site number: 1; 2;
Zinc binding site 1 out of 2 in 6sgp
Go back to
Zinc Binding Sites List in 6sgp
Zinc binding site 1 out
of 2 in the X-Ray Structure of Human Glutamate Carboxypeptidase II (Gcpii) - the E424M Inactive Mutant, in Complex with A Sulfamide Inhibitor Gluglu
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of X-Ray Structure of Human Glutamate Carboxypeptidase II (Gcpii) - the E424M Inactive Mutant, in Complex with A Sulfamide Inhibitor Gluglu within 5.0Å range:
|
Zinc binding site 2 out of 2 in 6sgp
Go back to
Zinc Binding Sites List in 6sgp
Zinc binding site 2 out
of 2 in the X-Ray Structure of Human Glutamate Carboxypeptidase II (Gcpii) - the E424M Inactive Mutant, in Complex with A Sulfamide Inhibitor Gluglu
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of X-Ray Structure of Human Glutamate Carboxypeptidase II (Gcpii) - the E424M Inactive Mutant, in Complex with A Sulfamide Inhibitor Gluglu within 5.0Å range:
|
Reference:
C.Barinka,
S.Shukla,
L.Motlova.
X-Ray Structure of Human Glutamate Carboxypeptidase II (Gcpii) - the E424M Inactive Mutant, in Complex with A Sulfamide Inhibitor Gluglu To Be Published.
Page generated: Tue Oct 29 07:21:45 2024
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