Zinc in PDB 6sc3: Thermolysin in Complex with Fragment J62

Enzymatic activity of Thermolysin in Complex with Fragment J62

All present enzymatic activity of Thermolysin in Complex with Fragment J62:
3.4.24.27;

Protein crystallography data

The structure of Thermolysin in Complex with Fragment J62, PDB code: 6sc3 was solved by F.Magari, A.Heine, G.Klebe, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 46.38 / 1.82
Space group P 61 2 2
Cell size a, b, c (Å), α, β, γ (°) 92.760, 92.760, 129.004, 90.00, 90.00, 120.00
R / Rfree (%) 16.4 / 20.5

Other elements in 6sc3:

The structure of Thermolysin in Complex with Fragment J62 also contains other interesting chemical elements:

Calcium (Ca) 4 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Thermolysin in Complex with Fragment J62 (pdb code 6sc3). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Thermolysin in Complex with Fragment J62, PDB code: 6sc3:

Zinc binding site 1 out of 1 in 6sc3

Go back to Zinc Binding Sites List in 6sc3
Zinc binding site 1 out of 1 in the Thermolysin in Complex with Fragment J62


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Thermolysin in Complex with Fragment J62 within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Zn405

b:17.8
occ:1.00
OE2 E:GLU166 1.9 16.1 1.0
O1 E:BCT406 2.0 17.0 1.0
NE2 E:HIS142 2.0 18.6 1.0
NE2 E:HIS146 2.1 18.8 1.0
C E:BCT406 2.5 27.1 1.0
O2 E:BCT406 2.7 23.8 1.0
CD E:GLU166 2.8 19.0 1.0
OE1 E:GLU166 2.9 18.7 1.0
CE1 E:HIS146 2.9 18.7 1.0
CE1 E:HIS142 2.9 16.2 1.0
CD2 E:HIS142 3.0 18.0 1.0
HE1 E:HIS146 3.1 22.5 1.0
HH E:TYR157 3.1 25.4 1.0
HE1 E:HIS142 3.1 19.5 1.0
CD2 E:HIS146 3.2 22.4 1.0
HD2 E:HIS142 3.2 21.7 1.0
HE2 E:HIS231 3.3 22.4 1.0
HD2 E:HIS146 3.4 26.9 1.0
OH E:TYR157 3.8 21.1 1.0
O3 E:BCT406 4.0 31.5 1.0
HA E:GLU166 4.0 18.9 1.0
NE2 E:HIS231 4.1 18.7 1.0
ND1 E:HIS142 4.1 17.9 1.0
ND1 E:HIS146 4.1 18.9 1.0
HB2 E:SER169 4.1 25.7 1.0
CG E:HIS142 4.1 18.3 1.0
CG E:GLU166 4.2 19.4 1.0
CG E:HIS146 4.2 16.6 1.0
HB3 E:SER169 4.3 25.7 1.0
HG2 E:GLU166 4.3 23.3 1.0
HE1 E:TYR157 4.4 20.7 1.0
HD2 E:HIS231 4.5 23.8 1.0
O E:DMS408 4.5 32.3 1.0
O E:HOH643 4.5 19.3 1.0
CB E:SER169 4.6 21.4 1.0
CD2 E:HIS231 4.6 19.8 1.0
S E:DMS408 4.7 54.9 1.0
HG3 E:GLU166 4.7 23.3 1.0
OE1 E:GLU143 4.7 22.4 1.0
OG E:SER169 4.8 18.3 1.0
CZ E:TYR157 4.8 19.8 1.0
HH22 E:ARG203 4.8 23.4 1.0
HD1 E:HIS142 4.8 21.5 1.0
OE2 E:GLU143 4.9 20.5 1.0
HD1 E:HIS146 4.9 22.7 1.0
CA E:GLU166 4.9 15.7 1.0
CE1 E:TYR157 4.9 17.2 1.0

Reference:

F.Magari, A.Heine, G.Klebe. Thermolysin in Complex with Fragment J62 To Be Published.
Page generated: Wed Dec 16 12:46:20 2020

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