Zinc in PDB 6r16: Crystal Structure of the SUN1-KASH4 6:6 Complex

The structure of Crystal Structure of the SUN1-KASH4 6:6 Complex, PDB code: 6r16 was solved by M.Gurusaran, O.R.Davies, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.83 / 2.75
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	104.370, 117.210, 138.420, 90.00, 90.00, 90.00
R / Rfree (%)	21.9 / 25.5

The structure of Crystal Structure of the SUN1-KASH4 6:6 Complex also contains other interesting chemical elements:

Potassium

(K)

6 atoms

The binding sites of Zinc atom in the Crystal Structure of the SUN1-KASH4 6:6 Complex (pdb code 6r16). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Crystal Structure of the SUN1-KASH4 6:6 Complex, PDB code: 6r16:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the Crystal Structure of the SUN1-KASH4 6:6 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the SUN1-KASH4 6:6 Complex within 5.0Å range: probe atom residue distance (Å) B Occ G:Zn501 b:55.1 occ:0.75 ND1 J:HIS384 2.1 0.3 1.0 SG J:CYS382 2.2 95.7 1.0 SG G:CYS382 2.3 82.5 1.0 SG G:CYS381 2.3 78.9 1.0 CG J:HIS384 3.0 0.6 1.0 CE1 J:HIS384 3.0 0.6 1.0 CB G:CYS382 3.1 78.8 1.0 N G:CYS382 3.2 78.4 1.0 CB G:CYS381 3.2 78.5 1.0 CB J:HIS384 3.3 0.1 1.0 C G:CYS381 3.6 80.1 1.0 CA G:CYS382 3.7 75.3 1.0 CB J:CYS382 3.8 90.9 1.0 CA G:CYS381 4.0 79.9 1.0 CB G:ALA385 4.0 81.3 1.0 NE2 J:HIS384 4.1 0.2 1.0 CD2 J:HIS384 4.1 0.9 1.0 N J:HIS384 4.2 93.1 1.0 CA J:HIS384 4.4 95.3 1.0 O G:CYS381 4.4 83.0 1.0 C G:CYS382 4.5 87.0 1.0 CA G:ALA385 4.5 87.9 1.0 N G:CYS381 4.6 85.8 1.0 N G:ALA385 4.7 87.3 1.0 O G:CYS382 4.7 88.8 1.0 N J:SER383 4.9 84.6 1.0

Zinc binding site 2 out of 3 in the Crystal Structure of the SUN1-KASH4 6:6 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of the SUN1-KASH4 6:6 Complex within 5.0Å range: probe atom residue distance (Å) B Occ H:Zn501 b:72.3 occ:0.31 ND1 K:HIS384 2.0 0.8 1.0 SG K:CYS382 2.3 0.1 1.0 SG H:CYS382 2.3 0.1 1.0 SG H:CYS381 2.3 0.6 1.0 CB H:CYS382 2.7 0.3 1.0 N H:CYS382 2.9 0.3 1.0 CE1 K:HIS384 3.0 1.0 1.0 CG K:HIS384 3.0 0.3 1.0 CB H:CYS381 3.3 0.8 1.0 CB K:HIS384 3.3 0.5 1.0 CA H:CYS382 3.4 0.9 1.0 C H:CYS381 3.6 0.8 1.0 CB K:CYS382 3.9 0.4 1.0 CA H:CYS381 4.0 0.8 1.0 NE2 K:HIS384 4.1 0.3 1.0 CD2 K:HIS384 4.1 0.8 1.0 N K:HIS384 4.2 0.2 1.0 O H:CYS381 4.4 0.3 1.0 CA K:HIS384 4.4 0.4 1.0 C H:CYS382 4.4 0.1 1.0 N H:CYS381 4.5 0.4 1.0 CB H:ALA385 4.7 0.9 1.0 O H:CYS382 4.8 0.8 1.0 N K:SER383 4.9 0.8 1.0

Zinc binding site 3 out of 3 in the Crystal Structure of the SUN1-KASH4 6:6 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of the SUN1-KASH4 6:6 Complex within 5.0Å range: probe atom residue distance (Å) B Occ I:Zn501 b:86.3 occ:0.19 ND1 L:HIS384 2.0 0.2 1.0 SG L:CYS382 2.3 0.1 1.0 SG I:CYS382 2.3 0.5 1.0 SG I:CYS381 2.3 0.8 1.0 CB I:CYS382 2.9 0.6 1.0 CE1 L:HIS384 2.9 1.0 1.0 CG L:HIS384 3.1 0.4 1.0 N I:CYS382 3.4 0.9 1.0 CB I:CYS381 3.4 0.3 1.0 C I:CYS381 3.4 0.4 1.0 CB L:HIS384 3.5 0.5 1.0 O I:CYS381 3.6 0.7 1.0 CB L:CYS382 3.7 0.6 1.0 CA I:CYS382 3.7 0.2 1.0 CA I:CYS381 4.0 0.2 1.0 NE2 L:HIS384 4.1 0.1 1.0 CD2 L:HIS384 4.2 0.4 1.0 N L:HIS384 4.3 0.3 1.0 CA L:HIS384 4.5 0.2 1.0 C I:CYS382 4.7 0.7 1.0 O I:HIS384 4.9 0.5 1.0 N I:CYS381 4.9 0.4 1.0 N L:SER383 4.9 0.6 1.0 CA L:CYS382 5.0 0.6 1.0

M.Gurusaran, O.R.Davies. Linc Complex Clustering Through Head-to-Head Assembly Provides A Novel Mechanism For Nuclear and Chromosomal Anchoring. To Be Published.